Výsledky vyhledávání

Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor

Autor: Ck, Goldman, Be, Rogers, Jt, Douglas, Ba, Sosnowski, Ying W, Gp, Siegal, Andrew Baird, Ja, Campain, Dt, Curiel

Publikováno v: Europe PubMed Central

Kaposi's sarcoma (KS) is a major AIDS-related malignancy associated with significant morbidity and mortality. Current chemotherapeutic regimens are associated with a dismal prognosis. In an effort to develop a new approach to KS treatment, we devised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::72b80cc4bff6890bd0a79fdea3021b5f
http://europepmc.org/abstract/med/9108444

Zobrazit plný text záznamu

Akademický článek

Characterization of macrocyclic peptide drug interactions with bile salts and biorelevant colloids via single amino acid mutations and ¹ H nuclear magnetic resonance (NMR) spectroscopy.

Autor: Dening TJ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, United States; Synthetic Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Napolitano JG; Synthetic Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Ochoa JL; Synthetic Molecule Pharmaceutical Sciences, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, United States., Douglas JT; Nuclear Magnetic Resonance Core Laboratory, The University of Kansas, Lawrence, KS 66047, United States., Hageman MJ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, United States. Electronic address: mhageman@ku.edu.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Jan; Vol. 114 (1), pp. 434-448. Date of Electronic Publication: 2024 Oct 24.

Zobrazit plný text záznamu

Akademický článek

β-Cyclodextrin derivatives bind aromatic side chains of the cyclic peptide lanreotide.

Autor: Jafari N; Pharmaceutical Chemistry, University of Kansas, USA. Electronic address: negar.jafari@ku.edu., Douglas JT; NMR Core Lab, University of Kansas, Lawrence, USA., Neuenswander SA; NMR Core Lab, University of Kansas, Lawrence, USA., Kelich P; Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, TX, USA., Hageman MJ; Pharmaceutical Chemistry, University of Kansas, USA; BIO Center, University of Kansas, Lawrence, USA. Electronic address: mhageman@ku.edu.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Nov 02. Date of Electronic Publication: 2024 Nov 02.

Zobrazit plný text záznamu

Akademický článek

My experience of person-centered and personalized care in early-stage primary progressive aphasia.

Autor: Douglas JT; The University of Alabama at Birmingham, USA.

Publikováno v: Dementia (London, England) [Dementia (London)] 2024 Aug 30, pp. 14713012241281006. Date of Electronic Publication: 2024 Aug 30.

Zobrazit plný text záznamu

Akademický článek

Tuning the redox profile of the 6,6'-biazulenic platform through functionalization along its molecular axis.

Autor: Kelsey SR; Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA. mbarybin@ku.edu., Griaznov G; Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA. mbarybin@ku.edu., Spaeth AD; Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA. mbarybin@ku.edu., Janzen DE; Department of Chemistry and Biochemistry, St. Catherine University, St. Paul, MN 55105, USA., Douglas JT; NMR Laboratory, Molecular Structures Group, University of Kansas, Lawrence, KS 66047, USA., Thompson WH; Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA. mbarybin@ku.edu., Barybin MV; Department of Chemistry, University of Kansas, Lawrence, KS 66045, USA. mbarybin@ku.edu.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 May 09; Vol. 60 (39), pp. 5213-5216. Date of Electronic Publication: 2024 May 09.

Zobrazit plný text záznamu

Akademický článek

Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes.

Autor: Devkota S; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS, USA., Zhou R; Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Nagarajan V; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS, USA., Maesako M; Alzheimer Research Unit, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Do H; Center for Computational Biology, University of Kansas, Lawrence, KS, USA., Noorani A; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS, USA., Overmeyer C; Graduate Program in Neurosciences, University of Kansas, Lawrence, KS, USA., Bhattarai S; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS, USA., Douglas JT; Nuclear Magnetic Resonance Core Lab, University of Kansas, Lawrence, KS, USA., Saraf A; Mass Spectrometry and Analytical Proteomic Laboratory, University of Kansas, Lawrence, KS, USA., Miao Y; Center for Computational Biology, University of Kansas, Lawrence, KS, USA; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, USA., Ackley BD; Department of Molecular Biosciences, University of Kansas, Lawrence, KS, USA., Shi Y; Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China; Westlake Laboratory of Life Science and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, and Institute of Biology, Westlake Institute for Advanced Study, Hangzhou, Zhejiang Province, China., Wolfe MS; Department of Medicinal Chemistry, University of Kansas, Lawrence, KS, USA; Graduate Program in Neurosciences, University of Kansas, Lawrence, KS, USA. Electronic address: mswolfe@ku.edu.

Publikováno v: Cell reports [Cell Rep] 2024 Feb 27; Vol. 43 (2), pp. 113761. Date of Electronic Publication: 2024 Feb 13.

Zobrazit plný text záznamu

Akademický článek

Use of phosphotyrosine-containing peptides to target SH2 domains: Antagonist peptides of the Crk/CrkL-p130Cas axis.

Autor: Douglas JT; Nuclear Magnetic Resonance Core Lab, University of Kansas, Lawrence, KS, United States., Johnson DK; Computational Chemical Biology Core, Molecular Graphics and Modeling Laboratory, University of Kansas, Lawrence, Kansas, United States., Roy A; High Throughput Screening Laboratory, University of Kansas, Lawrence, KS, United States., Park T; Department of Pediatrics, Children's Mercy Kansas City and University of Missouri Kansas City School of Medicine, Kansas City, MO, United States.

Publikováno v: Methods in enzymology [Methods Enzymol] 2024; Vol. 698, pp. 301-342. Date of Electronic Publication: 2024 Apr 27.

Zobrazit plný text záznamu

Akademický článek

Development of a Palliative Care Approach for Primary Progressive Aphasia: My Experience as a Person Living With This Rare Disorder.

Autor: Douglas JT; Volunteer, Department of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, The University of Alabama at Birmingham, USA.

Publikováno v: Journal of palliative care [J Palliat Care] 2023 Jul; Vol. 38 (3), pp. 276-281. Date of Electronic Publication: 2021 Jul 02.

Zobrazit plný text záznamu

Akademický článek

Vanadyl as a Spectroscopic Probe of Tunable Ligand Donor Strength in Bimetallic Complexes.

Autor: Dopp CM; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, Kansas 66045, United States., Golwankar RR; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, Kansas 66045, United States., Kelsey SR; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, Kansas 66045, United States., Douglas JT; Nuclear Magnetic Resonance Laboratory, Molecular Structures Group, University of Kansas, 2034 Becker Dr, Lawrence, Kansas 66047, United States., Erickson AN; Department of Chemistry, University of Memphis, 3744 Walker Avenue, Memphis, Tennessee 38152, United States., Oliver AG; Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States., Day CS; Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109, United States., Day VW; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, Kansas 66045, United States., Blakemore JD; Department of Chemistry, University of Kansas, 1567 Irving Hill Road, Lawrence, Kansas 66045, United States.

Publikováno v: Inorganic chemistry [Inorg Chem] 2023 Jun 26; Vol. 62 (25), pp. 9827-9843. Date of Electronic Publication: 2023 Jun 14.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání