Myocardial Carbohydrate, Ketone, and Fatty Acid Uptake in Conscious Lambs with Aortopulmonary Shunts1

Autor: M Dalinghaus, J. H. Koers, A. M. Gerding, F A J Muskiet, J. J. Meuzelaar, Jrg Kuipers, J. W. C. Gratama

Publikováno v: Pediatric Research. 32:27-32

A left to right shunt increases myocardial work and is often accompanied by increased catecholamine levels. Because both increased myocardial work and increased catecholamine levels may induce increased fatty acid utilization, which could increase re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b6239c31f00fb465d10c14275831778
https://doi.org/10.1203/00006450-199207000-00006

Genomics of the human carnitine acyltransferase genes

Autor: Nienke Huijkman, Beatrijs Bartelds, Christina Boomsma, Jrg Kuipers, FR van der Leij

Publikováno v: Molecular genetics and metabolism. 71(1-2)

Five genes in the human genome are known to encode different active forms of related carnitine acyltransferases: CPT1A for liver-type carnitine palmitoyltransferase I, CPT1B for muscle-type carnitine palmitoyltransferase I, CPT2 for carnitine palmito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0ee5fc90834d0fec01a40f685e3ac1
https://pubmed.ncbi.nlm.nih.gov/11001805

Cytological evidence that the C-terminus of carnitine palmitoyltransferase I is on the cytosolic face of the mitochondrial outer membrane

Autor: Victor A. Zammit, FR van der Leij, Beatrijs Bartelds, Anita M. Kram, Janny Takens, Han Roelofsen, Jrg Kuipers, Gioia B. Smid

Publikováno v: Biochemical Journal, 341, 777-784. PORTLAND PRESS LTD

Carnitine palmitoyltransferase I (CPT I) is a key enzyme in the regulation of β-oxidation. The topology of this enzyme has been difficult to elucidate by biochemical methods. We studied the topology of a fusion protein of muscle-type CPT I (M-CPT I)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962aa9ca21bb91e1cb4337f87e92af31
https://pubmed.ncbi.nlm.nih.gov/10417344

Cardiovascular adjustments to acute hypoxemia superimposed on chronic hypoxemia in lambs

Autor: J. W. C. Gratama, M Dalinghaus, Jrg Kuipers, Wg Zijlstra

Publikováno v: American Journal of Physiology, 268, H974-H979
American Journal of Physiology, 268, 3, pp. H974-H979
American Journal of Physiology-Heart and Circulatory Physiology, 268(3), H974-H979. AMER PHYSIOLOGICAL SOC

Cardiovascular responses to acute hypoxemia are in part mediated through adrenergic and chemoreceptor stimulation. In chronic hypoxemia the response to these stimuli may be blunted. Therefore, we determined whether the cardiovascular responses to acu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1546edf195995d00ff97fd6124cd84
http://hdl.handle.net/2066/21621

Body fluid compartment volumes in chronically hypoxemic lambs

Autor: M Vandeberg, M Dalinghaus, A. M. Gerding, J. W. C. Gratama, Kj Meuzelaar, Jh Koers, Wg Zijlstra, Jrg Kuipers

Publikováno v: Pediatric research. 33(3)

Chronic hypoxemia is associated with a decreased growth rate and a decreased rate of cell division. In lambs with experimental cyanotic heart disease, the gain in body mass was decreased. In this study, we determined to what extent the lower body mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21a8a206db1ef4620dda54fee00e1f2
https://pubmed.ncbi.nlm.nih.gov/8460063