Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jr-Ming Yang"'
Autor:
Suyang Wang, Chao-Cheng Chen, Ming-Hung Hu, Michelle Cheng, Hsin-Fang Tu, Ya-Chea Tsai, Jr-Ming Yang, T. C. Wu, Chuan-Hsiang Huang, Chien-Fu Hung
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Bacteria-based cancer therapy have demonstrated innovative strategies to combat tumors. Recent studies have focused on gram-negative bacterial outer membrane vesicles (OMVs) as a novel cancer immunotherapy strategy due to its intr
Externí odkaz:
https://doaj.org/article/bd73d6bad4df41d1a5e9db0941c51ce3
Autor:
Suyang Wang, Michelle Cheng, Chao-Cheng Chen, Chia-Yu Chang, Ya-Chea Tsai, Jr-Ming Yang, TC Wu, Chuan-Hsiang Huang, Chien-Fu Hung
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTBacteria-based cancer therapy employs various strategies to combat tumors, one of which is delivering tumor-associated antigen (TAA) to generate specific immunity. Here, we utilized a poly-arginine extended HPV E7 antigen (9RE7) for attachmen
Externí odkaz:
https://doaj.org/article/7cfdbd13bc2c4b00a9e47df279922ed5
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101611- (2022)
Summary: We recently developed a biosensor barcoding approach for highly multiplexed tracking of molecular activities in live cells. In this protocol, we detail the labeling of cells expressing different genetically encoded fluorescent biosensors wit
Externí odkaz:
https://doaj.org/article/b9209a680b114a0d9f5fc8fd0dec9642
Autor:
Jr-Ming Yang, Sayak Bhattacharya, Hoku West-Foyle, Chien-Fu Hung, T.-C. Wu, Pablo A. Iglesias, Chuan-Hsiang Huang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cellular ERK activation occurs as discrete pulses but their relationship to upstream Ras signaling is still under debate. Here, the authors show that Ras signaling associated with cellular protrusions triggers pulsed ERK activation, thereby enabling
Externí odkaz:
https://doaj.org/article/927f4aae162542e094c9ed33fbf33687
Autor:
Jr-Ming Yang, Sayak Bhattacharya, Hoku West-Foyle, Chien-Fu Hung, T.-C. Wu, Pablo A. Iglesias, Chuan-Hsiang Huang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
In the original version of this Article, the label “RTK” in Figure 6a was inadvertently changed to “RTE”. This has now been corrected in the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/bba63b61f61f4082a57bec3d89a8ab38
Autor:
Jr-Ming Yang, 楊之茗
91
The acid- and thermo-stable Sac7d is a small, non-specific DNA- binding protein of the hyperthermophile Archaea Sulfolobus acidocaldarius. In this thesis, Sac7d is employed as a functional unit in the design of a thermo-stable protein contain
The acid- and thermo-stable Sac7d is a small, non-specific DNA- binding protein of the hyperthermophile Archaea Sulfolobus acidocaldarius. In this thesis, Sac7d is employed as a functional unit in the design of a thermo-stable protein contain
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/73669478090441111263
Autor:
Jr Ming Yang, Wei-Yu Chi, Chuan Hsiang Huang, Jessica Liang, Pablo A. Iglesias, Saki Takayanagi
Publikováno v:
Cell
SUMMARY Genetically encoded fluorescent biosensors are powerful tools for monitoring biochemical activities in live cells, but their multiplexing capacity is limited by the available spectral space. We overcome this problem by developing a set of bar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9de242dbef7d5862af347d284e56288
http://europepmc.org/articles/PMC8686192
http://europepmc.org/articles/PMC8686192
Publikováno v:
Methods. :119-124
Many tumors are associated with deficiency of the tumor suppressor, PTEN, a PIP3 phosphatase that turns off PIP3 signaling. The major site of PTEN action is the plasma membrane, where PIP3 is produced by PI3 kinases. However, the mechanism and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd20e661e40530b80eb99b320ee29c83
https://doi.org/10.1016/j.ymeth.2014.10.018
https://doi.org/10.1016/j.ymeth.2014.10.018
Autor:
Jr Ming Yang, Stephen Jay Gould
Publikováno v:
Biochemical Society Transactions. 41:277-282
Proteins bud from cells in small single-membraned vesicles (~50–250 nm) that have the same topology as the cell. Known variously as exosomes and microvesicles (EMVs), these extracellular organelles are enriched for specific proteins, lipids, carboh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16675b66a1a04ad6bed502e3009dfa80
https://doi.org/10.1042/bst20120275
https://doi.org/10.1042/bst20120275
Publikováno v:
Journal of Biological Chemistry. 286:14383-14395
Animal cells secrete small vesicles, otherwise known as exosomes and microvesicles (EMVs). A short, N-terminal acylation tag can target a highly oligomeric cytoplasmic protein, TyA, into secreted vesicles (Fang, Y., Wu, N., Gan, X., Yan, W., Morell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe954e58974c186aa012e0ec73613f7
https://doi.org/10.1074/jbc.m110.208660
https://doi.org/10.1074/jbc.m110.208660