Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jr-Jiun Liu"'
Autor:
Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen, Kwang-Yu Chang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-16 (2019)
Abstract Background Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. Methods Resistant cell
Externí odkaz:
https://doaj.org/article/a4d420e0b4e94a6d81430e61fa42269e
Autor:
Kwang-Yu Chang, Tsung-I. Hsu, Che-Chia Hsu, Shan-Yin Tsai, Jr-Jiun Liu, Shao-Wen Chou, Ming-Sheng Liu, Jing-Ping Liou, Chiung-Yuan Ko, Kai-Yun Chen, Jan-Jong Hung, Wen-Chang Chang, Cheng-Keng Chuang, Tzu-Jen Kao, Jian-Ying Chuang
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 655-664 (2017)
Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O6-methylguan
Externí odkaz:
https://doaj.org/article/2cfb7d3e1f924bd3bbb0af1a34f9768a
Autor:
Jr-Jiun Liu, 劉芷君
102
Anaplastic thyroid carcinoma (ATC) is the most malignant thyroid cancer. A majority of patients can only survive for 3 to 5 months after diagnosed. There are various treatment options for ATC including surgery, chemotherapy, radiation therap
Anaplastic thyroid carcinoma (ATC) is the most malignant thyroid cancer. A majority of patients can only survive for 3 to 5 months after diagnosed. There are various treatment options for ATC including surgery, chemotherapy, radiation therap
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/uvnytr
Autor:
Jr-Jiun Liu, Tsung-I Hsu, Jing-Ping Liou, Jian-Ying Chuang, Wen Chang Chang, Jia Yi Wang, Kwang-Yu Chang, Pin-Yuan Chen, Ruei Ming Chen, Shiu Hwa Yeh, Shung-Tai Yang, Wen Bin Yang, Che-Chia Hsu
Publikováno v:
Neuro Oncol
Background Glioblastoma is associated with poor prognosis and high mortality. Although the use of first-line temozolomide can reduce tumor growth, therapy-induced stress drives stem cells out of quiescence, leading to chemoresistance and glioblastoma
Autor:
Kelvin K C Tsai, Tsung I. Hsu, Jian Ying Chuang, Cheng-Keng Chuang, Chih Ta Huang, Jan Jong Hung, Jr Jiun Liu, Che Chia Hsu, Wen Chang Chang, Kwang Yu Chang
Publikováno v:
Biochemical and Biophysical Research Communications. 493:14-19
It has been suggested that stress stimuli from the microenvironment maintain a subset of tumor cells with stem-like properties, including drug resistance. Here, we investigate whether Sp1, a stress-responsive factor, regulates stemness gene expressio
Autor:
Shao Wen Chou, Jan Jong Hung, Shan Yin Tsai, Wen Chang Chang, Jian Ying Chuang, Jr Jiun Liu, Kwang Yu Chang, Tzu Jen Kao, Che Chia Hsu, Cheng-Keng Chuang, Ming Sheng Liu, Tsung I. Hsu, Kai Yun Chen, Chiung Yuan Ko, Jing Ping Liou
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 655-664 (2017)
Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O6-methylguan
Autor:
Kwang Yu Chang, Wen Bin Yang, Ming Sheng Liu, Pei Hsuan Chung, Tsung I. Hsu, Ka Yen Yang, Shao Wen Chou, Jian Ying Chuang, Pin Yuan Chen, Wei Lun Lo, Shang Hung Chen, Shun Tai Yang, Jui Mei Chu, Jr Jiun Liu, Chia Hung Chien, Chih Yuan Huang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-16 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
Background Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. Methods Resistant cell lines der
Autor:
Chia-Hung Chien, Chuang, Jian-Ying, Shun-Tai Yang, Yang, Wen-Bin, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Lo, Wei-Lun, Ka-Yen Yang, Liu, Ming-Sheng, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Chou, Shao-Wen, Shang-Hung Chen, Kwang-Yu Chang
Additional file 3: Figure S3. The mitochondrial ROS were detected with MitoSox. (A) The TMZ-induced mitochondrial ROS were in parental and resistant U87MG cells. (B) The MitoSox results of CD133+ cells from U87MG parental and resistant cells were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942fe1a33e3b1b1311b17b2105558c78
Autor:
Tsung I. Hsu, Jr Jiun Liu, Jing Ping Liou, Jian Ying Chuang, Shiu Hwa Yeh, Chiung Yuan Ko, Che-Chia Hsu, Kwang Yu Chang, Wen Chang Chang, Jia Yi Wang
Publikováno v:
Journal of Biomedical Science
Background Glioma stem-like cells (GSCs) are proposed to be responsible for high resistance in glioblastoma multiforme (GBM) treatment. In order to find new strategies aimed at reducing GSC stemness and improving GBM patient survival, we investigated
Autor:
Che-Chia Hsu, Chang, Wen-Chang, Tsung-I Hsu, Jr-Jiun Liu, Shiu-Hwa Yeh, Wang, Jia-Yi, Liou, Jing-Ping, Chiung-Yuan Ko, Kwang-Yu Chang, Chuang, Jian-Ying
Supplementary information includes Figures S1 to S3 and supplementary methods. (DOCX 654Â kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f75990d3987500730e9a5fbf543cc8