Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jr Je Darnell"'
Autor:
Michele Mietus-Snyder, S K Karathanasis, Frances M. Sladek, Jr Je Darnell, J A Ladias, Geoffrey S. Ginsburg, CF Kuo
Publikováno v:
Molecular and Cellular Biology. 12:1708-1718
Apolipoprotein CIII (apoCIII), a lipid-binding protein involved in the transport of triglycerides and cholesterol in the plasma, is synthesized primarily in the liver and the intestine. A cis-acting regulatory element, C3P, located at -90 to -66 upst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc7c58f2d8ff2608cfcd325ff650f5e
https://doi.org/10.1128/mcb.12.4.1708
https://doi.org/10.1128/mcb.12.4.1708
Publikováno v:
Molecular and Cellular Biology. 10:1841-1852
In situ hybridization and other data showed that all hepatocytes express glutathione-S-transferase (GST) Ya mRNA but that specifically pericentral cells can be induced 15- to 20-fold with 3-methylcholanthrene (3-MC). In order to identify DNA sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14ee259f3ce32f1dc4247467cba039b3
https://doi.org/10.1128/mcb.10.5.1841
https://doi.org/10.1128/mcb.10.5.1841
Autor:
C Schindler, Jr Je Darnell
Publikováno v:
Annual review of biochemistry. 64
Cytokines and growth factors regulate multiple aspects of cell growth through their interactions with specific receptors. These receptors initiate signals directed at both the cytoplasmic and the nuclear compartments. Many of the nuclear signals culm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5953dd2bc6834bbccc325e83c9f82e7c
https://pubmed.ncbi.nlm.nih.gov/7574495
https://pubmed.ncbi.nlm.nih.gov/7574495
Publikováno v:
The EMBO journal. 10(4)
We have investigated events following treatment of cells with interferon-gamma (IFN-gamma) that lead to the immediate transcriptional activation of an inducible gene. A gamma-interferon activation factor (GAF) was activated in the cytoplasm of human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8830e27b88074e7fc3b8470f20a3e321
https://pubmed.ncbi.nlm.nih.gov/1901265
https://pubmed.ncbi.nlm.nih.gov/1901265
Publikováno v:
Molecular and cellular biology. 10(6)
Interferon-stimulated gene factor 2 (ISGF2) was purified from HeLa cells treated with alpha interferon. The factor, a single polypeptide of 56 kilodaltons (kDa), bound both to the central 9 base pairs of the 15-base-pair interferon-stimulated respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbf8c42995d8a3bcf8ba99b0a0fcd73
https://pubmed.ncbi.nlm.nih.gov/2342456
https://pubmed.ncbi.nlm.nih.gov/2342456
Publikováno v:
Development (Cambridge, England). 109(2)
C/EBP is a positive-acting transcription factor important for hepatocyte-specific expression present not only in hepatocytes but also a limited number of other cell types in adult mice. By Northern blot analysis and in situ hybridization experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20514d847805358fdac6c61e6baa1154
https://pubmed.ncbi.nlm.nih.gov/2401206
https://pubmed.ncbi.nlm.nih.gov/2401206
Publikováno v:
Journal of Virology. 62:114-119
Interferon treatment of cell cultures results in the rapid transcriptional induction of a specific set of genes. In this paper we explore the effect of cellular infection by several adenoviruses, both wild type and mutant, on the expression of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6670f08c94a47e1315270e54f36e6c31
https://doi.org/10.1128/jvi.62.1.114-119.1988
https://doi.org/10.1128/jvi.62.1.114-119.1988
Publikováno v:
Molecular and Cellular Biology. 1:188-198
We have further analyzed the metabolism of specific messenger ribonucleic acid (mRNA) sequences within the cytoplasmic and nuclear RNA of Chinese hamster ovary (CHO) cells by using a set of previously constructed complementary deoxyribonucleic acid (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::074215acaaafcb0dca1a4e5a0da83fad
https://doi.org/10.1128/mcb.1.2.188
https://doi.org/10.1128/mcb.1.2.188
Publikováno v:
Molecular and Cellular Biology. 4:1929-1934
The maintenance of high levels of two liver-specific mRNAs in cultured hepatocytes was achieved in a serum-free hormonally defined cell culture medium. However, this maintenance of liver-specific mRNA levels did not correlate with the level of transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39437b4feb25a8c66d6ec5d3b522488d
https://doi.org/10.1128/mcb.4.9.1929
https://doi.org/10.1128/mcb.4.9.1929
Publikováno v:
Journal of Molecular Biology. 193:643-650
Cell-specific utilization of the albumin and immunoglobulin promoters within non-replicating adenovirus genomes has been established. With such viruses plus helper viruses we now consider the impact of infection by replicating viruses on liver-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c638f1c3034e6203952eefa9dcf688b
https://doi.org/10.1016/0022-2836(87)90347-0
https://doi.org/10.1016/0022-2836(87)90347-0