Inhibition of T cell activation by a monoclonal antibody reactive against the alpha 3 domain of human MHC class I molecules

Autor: Dm, Smith, Ja, Bluestone, Dr, Jeyarajah, Mh, Newberg, Victor Engelhard, Jr, Thistlethwaite, Es, Woodle

Publikováno v: Europe PubMed Central

A long term goal of investigators working in our laboratory has been to develop new mAbs for use as immunosuppressive agents. As a means toward achieving this goal, several new mAbs (hybridomas) have been developed by screening fusions for supernatan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d69c42e1fe2362d4105a75900b7fa27f
https://pubmed.ncbi.nlm.nih.gov/7913109

Liver Transplantation, Including the Concept of Reduced-size Liver Transplants in Children

Autor: Jean C. Emond, D. A. Rouch, Jr Jr Thistlethwaite, Christoph E. Broelsch, Alfred L. Baker, Peter P. Aran, J. L. Lichtor, Aaron R. Zucker, Peter F. Whitington

Publikováno v: Annals of Surgery. 208:410-420

Since the establishment of a clinical program in liver transplantation in 1984, 162 liver transplants have been performed in 131 patients (78 adults, 53 children). The patient mortality rate while waiting for a suitable organ has been 8% for adults a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3895c7246751cf142ec8d6fc76febb3
https://doi.org/10.1097/00000658-198810000-00003

Cutting edge: Membrane lymphotoxin regulates CD8+ T cell-mediated intestinal allograft rejection

Autor: Yang Xin Fu, P Zhou, Maria-Luisa Alegre, L Meng, G He, Q Wu, Jr Jr Thistlethwaite, Zhu Guo, O Kim, J Hart, Kenneth A. Newell, Jun Wang

Publikováno v: Scopus-Elsevier

Blocking the CD28/B7 and/or CD154/CD40 costimulatory pathways promotes long-term allograft survival in many transplant models where CD4+ T cells are necessary for rejection. When CD8+ T cells are sufficient to mediate rejection, these approaches fail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e90e752aad6c68438522da6a4de9e3
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035501035&partnerID=MN8TOARS

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Gender and race/ethnicity differences in living kidney donor demographics: Preference or disparity?

Autor: Ross LF; Carolyn and Matthew Bucksbaum Professor of Clinical Ethics, Professor of Pediatrics, Medicine, Surgery and the College, Associate Director of the MacLean Center for Clinical Medical Ethics, Co-Director of the Institute for Translational Medicine, University of Chicago, United States of America. Electronic address: Lross@uchicago.edu., Thistlethwaite JR; Professor Emeritus of Surgery, Section on Transplantation Surgery, Faculty Emeritus of the MacLean Center for Clinical Medical Ethics, University of Chicago, United States of America.

Publikováno v: Transplantation reviews (Orlando, Fla.) [Transplant Rev (Orlando)] 2021 Jul; Vol. 35 (3), pp. 100614. Date of Electronic Publication: 2021 Apr 09.