Yeast Solutions and Hyperpolarization Enable Real-Time Observation of Metabolized Substrates Even at Natural Abundance.

Autor: Peters JP; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany., Assaf C; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany., Mohamad FH; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany., Beitz E; Pharmaceutical Institute, CAU Kiel, Gutenbergstr. 76, Kiel 24118, Germany., Tiwari S; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany., Aden K; Institute of Clinical Molecular Biology, Kiel University, Gut Rosalind-Franklin-Straße 12, Kiel 24105, Germany.; Department of Internal Medicine I, University Medical Center Kiel, Arnold-Heller-Straße 3, Kiel 24105, Germany., Hövener JB; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany., Pravdivtsev AN; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany.

Publikováno v: Analytical chemistry [Anal Chem] 2024 Oct 29; Vol. 96 (43), pp. 17135-17144. Date of Electronic Publication: 2024 Oct 15.

High-Resolution Characterization of DNA/Protein Complexes in Living Bacteria.

Autor: Becker NA; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA., Peters JP; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.; Department of Chemistry and Biochemistry, University of Northern Iowa, Cedar Falls, IA, USA., James Maher L 3rd; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. maher@mayo.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2819, pp. 103-123.

Nitrogen-15 dynamic nuclear polarization of nicotinamide derivatives in biocompatible solutions.

Autor: Peters JP; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Brahms A; Otto Diels Institute for Organic Chemistry, Kiel University, Otto-Hahn Platz 4, 24098 Kiel, Germany., Janicaud V; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Anikeeva M; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Peschke E; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Ellermann F; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Ferrari A; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Hellmold D; Department of Neurosurgery, University Medical Center Kiel, Arnold-Heller-Str. 3, House D, 24105 Kiel, Germany., Held-Feindt J; Department of Neurosurgery, University Medical Center Kiel, Arnold-Heller-Str. 3, House D, 24105 Kiel, Germany., Kim NM; Institute of Clinical Molecular Biology, Kiel University, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Meiser J; Cancer Metabolism Group, Department of Cancer Research, Luxembourg Institute of Health, 6A Rue Nicolas-Ernest Barblé, 1210 Luxembourg, Luxembourg., Aden K; Institute of Clinical Molecular Biology, Kiel University, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany.; Department of Internal Medicine I, University Medical Center Kiel, Kiel, Germany., Herges R; Otto Diels Institute for Organic Chemistry, Kiel University, Otto-Hahn Platz 4, 24098 Kiel, Germany., Hövener JB; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany., Pravdivtsev AN; Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 14, 24118 Kiel, Germany.

Publikováno v: Science advances [Sci Adv] 2023 Aug 25; Vol. 9 (34), pp. eadd3643. Date of Electronic Publication: 2023 Aug 23.

Rare coding variants in ten genes confer substantial risk for schizophrenia.

Autor: Singh T; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. tsingh@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. tsingh@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. tsingh@broadinstitute.org., Poterba T; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Curtis D; UCL Genetics Institute, University College London, London, UK.; Centre for Psychiatry, Queen Mary University London, London, UK., Akil H; Department of Psychiatry, Michigan Neuroscience Institute, Medical School, University of Michigan, Ann Arbor, MI, USA., Al Eissa M; Division of Psychiatry, University College London, London, UK., Barchas JD; Weill Cornell Medical College, New York, NY, USA., Bass N; Division of Psychiatry, University College London, London, UK., Bigdeli TB; Department of Psychiatry and Behavioral Sciences, SUNY Downstate College of Medicine, Brooklyn, NY, USA., Breen G; Social Genetic and Developmental Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Bromet EJ; Department of Psychiatry and Behavioral Health, Health Sciences Center, Stony Brook University, Stony Brook, NY, USA., Buckley PF; Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA., Bunney WE; Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA., Bybjerg-Grauholm J; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Byerley WF; Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA., Chapman SB; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chen WJ; College of Public Health, National Taiwan University, Taipei, Taiwan., Churchhouse C; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Craddock N; National Centre for Mental Health, Cardiff University, Cardiff, UK., Cusick CM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., DeLisi L; Department of Psychiatry, Cambridge Health Alliance, Cambridge Hospital, Cambridge, MA, USA., Dodge S; Genomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Escamilla MA; Texas Tech University Health Sciences Center, El Paso, TX, USA., Eskelinen S; University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Public Health Solutions, Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland., Fanous AH; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Medical Center, Brooklyn, NY, USA., Faraone SV; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA., Fiorentino A; Division of Psychiatry, University College London, London, UK., Francioli L; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Gabriel SB; Genomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gage D; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gagliano Taliun SA; Faculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.; Montréal Heart Institute, Montreal, Quebec, Canada., Ganna A; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Genovese G; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Glahn DC; Department of Psychiatry, Boston Children's Hospital, Boston, MA, USA., Grove J; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Department of Biomedicine and Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark., Hall MH; McLean Hospital, Harvard Medical School, Belmont, MA, USA., Hämäläinen E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Heyne HO; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Holi M; Department of Psychiatry, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Hougaard DM; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Huang H; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hwu HG; Department of Psychiatry, National Taiwan University, Taipei, Taiwan., Kahn RS; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; MIRECC, JP Peters VA Hospital, Bronx, NY, USA., Kang HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Karczewski KJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kirov G; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Knowles JA; Department of Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY, USA., Lee FS; Weill Cornell Medical College, New York, NY, USA., Lehrer DS; Department of Psychiatry, Wright State University, Dayton, OH, USA., Lescai F; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Malaspina D; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Marder SR; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., McCarroll SA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., McIntosh AM; University of Edinburgh, Edinburgh, UK., Medeiros H; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Medical Center, Brooklyn, NY, USA., Milani L; Institute of Genomics, University of Tartu, Tartu, Estonia., Morley CP; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA.; Department of Public Health and Preventive Medicine and Department of Family Medicine, SUNY Upstate Medical University, Syracuse, NY, USA., Morris DW; National University of Ireland, Galway, Ireland., Mortensen PB; Aarhus University, Aarhus, Denmark., Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Nordentoft M; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Copenhagen Research Center for Mental Health, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., O'Brien NL; Division of Psychiatry, University College London, London, UK., Olivares AM; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ongur D; McLean Hospital, Harvard Medical School, Belmont, MA, USA., Ouwehand WH; University of Cambridge, Cambridge, UK., Palmer DS; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Paunio T; Department of Psychiatry, University of Helsinki, Helsinki, Finland., Quested D; Oxford Health NHS Foundation Trust, Oxford, UK., Rapaport MH; Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA., Rees E; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Rollins B; Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA., Satterstrom FK; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA., Schatzberg A; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Scolnick E; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Sharp SI; Division of Psychiatry, University College London, London, UK., Sklar P; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Sobell JL; Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Solomonson M; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Stahl EA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Stevens CR; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Suvisaari J; Finnish Institute for Health and Welfare, Helsinki, Finland., Tiao G; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Watson SJ; Department of Psychiatry, Michigan Neuroscience Institute, Medical School, University of Michigan, Ann Arbor, MI, USA., Watts NA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Blackwood DH; Department of Psychiatry, University of Edinburgh, Edinburgh, UK., Børglum AD; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Department of Biomedicine and Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Cohen BM; McLean Hospital, Harvard Medical School, Belmont, MA, USA., Corvin AP; Trinity College Dublin, Dublin, Ireland., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Freimer NB; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Glatt SJ; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, NY, USA., Hultman CM; School of Medicine, Johns Hopkins University, Baltimore, MD, USA., McQuillin A; Division of Psychiatry, University College London, London, UK., Palotie A; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Pato CN; Department of Psychiatry and Behavioral Sciences, SUNY Downstate College of Medicine, Brooklyn, NY, USA., Pato MT; Department of Psychiatry and Behavioral Sciences, SUNY Downstate College of Medicine, Brooklyn, NY, USA., Pulver AE; School of Medicine, Johns Hopkins University, Baltimore, MD, USA., St Clair D; University of Aberdeen, Aberdeen, UK., Tsuang MT; Center for Behavioral Genomics, Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA., Vawter MP; Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA., Walters JT; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Werge TM; Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark.; Center for GeoGenetics, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark., Ophoff RA; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, Erasmus Medical Center, Erasmus University, Rotterdam, the Netherlands., Sullivan PF; Karolinska Institute, Solna, Sweden.; University of North Carolina, Chapel Hill, NC, USA., Owen MJ; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., O'Donovan MC; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK., Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. bneale@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. bneale@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. bneale@broadinstitute.org., Daly MJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA. mjdaly@atgu.mgh.harvard.edu.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. mjdaly@atgu.mgh.harvard.edu.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. mjdaly@atgu.mgh.harvard.edu.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland. mjdaly@atgu.mgh.harvard.edu.

Publikováno v: Nature [Nature] 2022 Apr; Vol. 604 (7906), pp. 509-516. Date of Electronic Publication: 2022 Apr 08.

Examining the Effects of Netropsin on the Curvature of DNA A-Tracts Using Electrophoresis.

Autor: Miller J; Department of Chemistry and Biochemistry, University of Northern Iowa, 1227 West 27th Street, Cedar Falls, IA 50614, USA., Peters JP; Department of Chemistry and Biochemistry, University of Northern Iowa, 1227 West 27th Street, Cedar Falls, IA 50614, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Sep 28; Vol. 26 (19). Date of Electronic Publication: 2021 Sep 28.