Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Jp, Whitelegge"'
Autor:
Jp, Whitelegge, Ahn V, Aj, Norris, Sung H, Waring A, Rl, Stevens, Cb, Fluharty, Gilbert Privé, Kf, Faull, Al, Fluharty
Publikováno v:
Europe PubMed Central
Humans deficient in the cerebroside-sulfate activator protein (CSAct or Saposin B) are unable to catabolize sulfatide and other glycosphingolipids leading to their accumulation and neurodegenerative disease. Clinically this usually manifests as a for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::667d1730586f947e9267f7e0465d9531
https://pubmed.ncbi.nlm.nih.gov/14528917
https://pubmed.ncbi.nlm.nih.gov/14528917
Autor:
Patel S; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Ganbold K; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Cho CH; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Siddiqui J; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Yildiz R; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Sparman N; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Sadeh S; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Nguyen CM; Department of Biological Chemistry, University of California, Irvine, CA, 92697, USA., Wang J; Department of Pathology and Laboratory Medicine and Department of Biological Chemistry, University of California, Los Angeles, CA, 90095, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, NPI-Semel Institute, University of California, Los Angeles, CA, 90095, USA., Fried SK; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Waki H; Department of Metabolism and Endocrinology, Graduate School of Medicine, Akita University, Akita, Japan., Villanueva CJ; Molecular, Cellular, and Integrative Physiology Program, and Department of Integrative Biology and Physiology, University of California, Los Angeles, CA, 90095, USA., Seldin MM; Department of Biological Chemistry, University of California, Irvine, CA, 92697, USA., Sakaguchi S; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Vienna, Austria., Ellmeier W; Medical University of Vienna, Center for Pathophysiology, Infectiology and Immunology, Institute of Immunology, Vienna, Austria., Tontonoz P; Department of Pathology and Laboratory Medicine and Department of Biological Chemistry, University of California, Los Angeles, CA, 90095, USA., Rajbhandari P; Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. prashant.rajbhandari@mssm.edu.; Disease Mechanism and Therapeutics Program, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. prashant.rajbhandari@mssm.edu.
Publikováno v:
Nature communications [Nat Commun] 2024 Oct 02; Vol. 15 (1), pp. 8533. Date of Electronic Publication: 2024 Oct 02.
Autor:
Breen B; School of Molecular Sciences, Center for Bioenergy and Photosynthesis, Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, Arizona, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, NPI-Semel Institute, University of California Los Angeles, Los Angeles, California, USA., Wachter RM; School of Molecular Sciences, Center for Bioenergy and Photosynthesis, Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, Arizona, USA.
Publikováno v:
Protein science : a publication of the Protein Society [Protein Sci] 2024 Jul; Vol. 33 (7), pp. e5069.
Autor:
Yano J; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Molecular, Cellular & Integrative Physiology Interdepartmental PhD Program, UCLA, Los Angeles, CA 90095, USA., Nave C; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Larratt K; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Honey P; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Department of Neuroscience, Wellesley College, Wellesley, MA 02481, USA., Roberts M; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Jingco C; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Fung ML; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Trotter D; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Molecular, Cellular & Integrative Physiology Interdepartmental PhD Program, UCLA, Los Angeles, CA 90095, USA., He X; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Elezi G; Pasarow Mass Spectrometry Laboratory, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Cotsen Institute of Archaeology, UCLA, Los Angeles, CA 90095, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Wasserman S; Department of Neuroscience, Wellesley College, Wellesley, MA 02481, USA., Donlea JM; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: jdonlea@ucla.edu.
Publikováno v:
Current biology : CB [Curr Biol] 2024 Jun 03; Vol. 34 (11), pp. 2487-2501.e3. Date of Electronic Publication: 2024 May 20.
Publikováno v:
Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2024 Mar 06; Vol. 35 (3), pp. 402-405.
Autor:
Chen M; Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095 USA., Kálai T; Institute of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Pécs, Szigeti St. 12, Pecs, 7624 Hungary., Cascio D; Department of Biological Chemistry, UCLA-DOE Institute, Howard Hughes Medical Institute, and Molecular Biology Institute, University of California, Los Angeles, CA 90095 USA., Bridges MD; Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095 USA., Whitelegge JP; The Pasarow Mass Spectrometry Laboratory, David Geffen School of Medicine, The Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095 USA., Elgeti M; Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095 USA.; Present Address: Institute for Drug Discovery, Leipzig University Medical Center, Härtelstr. 16-18, 04107 Leipzig, Germany., Hubbell WL; Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095 USA.
Publikováno v:
Applied magnetic resonance [Appl Magn Reson] 2024; Vol. 55 (1-3), pp. 251-277. Date of Electronic Publication: 2023 Oct 14.
Autor:
Dey D; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Qing E; Department of Microbiology and Immunology, Loyola University Chicago, Maywood, IL, 60153, USA., He Y; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA., Chen Y; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA., Jennings B; Department of Internal Medicine, Hematology Division, Washington University School of Medicine, St. Louis, MO, 63110, USA., Cohn W; Pasarow Mass Spectrometry Laboratory, The Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Singh S; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Gakhar L; Department of Biochemistry and Molecular Biology, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.; Protein and Crystallography Facility, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.; PAQ Therapeutics, Burlington, MA, 01803, USA., Schnicker NJ; Protein and Crystallography Facility, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA., Pierce BG; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA.; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, 20742, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, The Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, 90095, USA., Doray B; Department of Internal Medicine, Hematology Division, Washington University School of Medicine, St. Louis, MO, 63110, USA., Orban J; University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, MD, 20850, USA.; Department of Chemistry and Biochemistry, University of Maryland, College Park, MD, 20742, USA., Gallagher T; Department of Microbiology and Immunology, Loyola University Chicago, Maywood, IL, 60153, USA., Hasan SS; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA. sshasan@som.umaryland.edu.; University of Maryland Marlene and Stewart Greenebaum Cancer Center, University of Maryland Medical Center, Baltimore, MD, 21201, USA. sshasan@som.umaryland.edu.; Center for Biomolecular Therapeutics, University of Maryland School of Medicine, Rockville, MD, 20850, USA. sshasan@som.umaryland.edu.
Publikováno v:
Nature communications [Nat Commun] 2023 Dec 15; Vol. 14 (1), pp. 8358. Date of Electronic Publication: 2023 Dec 15.
Autor:
Lantz C; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States., Lopez J; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States., Goring AK; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States., Zenaidee MA; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States.; Australian Proteome Analysis Facility, Macquarie University, Macquarie Park, New South Wales 2109, Australia., Biggs K; Department of Neurology and Brain Research Institute, David Geffen School of Medicine at UCLA, University of California─Los Angeles, Los Angeles, California 90095, United States., Whitelegge JP; The Pasarow Mass Spectrometry Laboratory, The Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, University of California─Los Angeles, Los Angeles, California 90095, United States., Ogorzalek Loo RR; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States., Klärner FG; Institute of Chemistry, University of Duisburg-Essen, Essen 45141, Germany., Schrader T; Institute of Chemistry, University of Duisburg-Essen, Essen 45141, Germany., Bitan G; Department of Neurology and Brain Research Institute, David Geffen School of Medicine at UCLA, University of California─Los Angeles, Los Angeles, California 90095, United States.; Molecular Biology Institute, University of California─Los Angeles, Los Angeles, California 90095, United States., Loo JA; Department of Chemistry and Biochemistry, University of California─Los Angeles, Los Angeles, California 90095, United States.; Molecular Biology Institute, University of California─Los Angeles, Los Angeles, California 90095, United States.; Department of Biological Chemistry, David Geffen School of Medicine at UCLA, University of California─Los Angeles, Los Angeles, California 90095, United States.
Publikováno v:
Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2023 Dec 06; Vol. 34 (12), pp. 2739-2747. Date of Electronic Publication: 2023 Nov 07.
Autor:
Yano J; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Molecular, Cellular & Integrative Physiology Interdepartmental PhD Program, UCLA, Los Angeles, CA 90095, USA., Nave C; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Larratt K; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Honey P; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Department of Neuroscience, Wellesley College, Wellesley, MA 02481, USA., Jingco C; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Roberts M; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Trotter D; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Molecular, Cellular & Integrative Physiology Interdepartmental PhD Program, UCLA, Los Angeles, CA 90095, USA., He X; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Elezi G; Pasarow Mass Spectrometry Laboratory, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.; Cotsen Institute of Archaeology, UCLA, Los Angeles, CA 90095, USA., Whitelegge JP; Pasarow Mass Spectrometry Laboratory, Jane & Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA., Wasserman S; Department of Neuroscience, Wellesley College, Wellesley, MA 02481, USA., Donlea JM; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 May 28. Date of Electronic Publication: 2023 May 28.