Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Jp, Moulinoux"'
Publikováno v:
Europe PubMed Central
Dimethylsilane tetramines are structural analogues of spermine with a (CH3)2 Si-group incorporated into the central carbon chain. They have potential as anticancer drugs. Their cytotoxic effect was considered to rely mainly on their polyamine antagon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9741ec9158ffc2dbdf7df4a8aacc2a1d
https://pubmed.ncbi.nlm.nih.gov/12552990
https://pubmed.ncbi.nlm.nih.gov/12552990
Publikováno v:
Europe PubMed Central
It has previously been demonstrated that during Lewis Lung carcinoma growth, red blood cell spermidine levels increase concomitantly with tumor volume. If [14C] putrescine or 2-methylputrescine are administered, [14C] spermidine and methylspermidine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e8bf5cf1919110478192fddd5db4686
https://pubmed.ncbi.nlm.nih.gov/9042251
https://pubmed.ncbi.nlm.nih.gov/9042251
Autor:
N Seiler, JP Moulinoux
Publikováno v:
médecine/sciences. 12:745
Le metabolisme des polyamines etant fortement active dans les cellules cancereuses, l'inhibition de la synthese de ces molecules a constitue une cible pour l'industrie pharmaceutique. Mais une succession d'echecs a rendu sceptique quant a cette voie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f65a71e330b0a89ade0e7e0539991a21
https://doi.org/10.4267/10608/815
https://doi.org/10.4267/10608/815
Publikováno v:
Europe PubMed Central
High red blood cell (RBC) spermidine levels have been observed in patients harboring various histological types of cancer. In an attempt to explain the mechanism of RBC spermidine uptake in the malignant cell growth process, erythrocytes from normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d404d13b22a1d69faa4517ee6d0d17e6
https://pubmed.ncbi.nlm.nih.gov/2817786
https://pubmed.ncbi.nlm.nih.gov/2817786
Publikováno v:
Europe PubMed Central
Bis(7-amino-4-azaheptyl)dimethylsilane (AzhepSi) and its bis(ethyl) derivative [bis(7-ethylamino-4-azaheptyl)dimethylsilane] (EtAzhepSi) are the first examples of a new type of aliphatic tetramine with a dimethylsilane group incorporated into the cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dd7a283d3549702c7367071596b48f8b
http://europepmc.org/abstract/med/8971167
http://europepmc.org/abstract/med/8971167
Publikováno v:
Europe PubMed Central
Using antipolyamine antibodies covalently bound to magnetic latex spheres, we have been able to isolate from the plasma of mice bearing the Lewis lung carcinoma, 8 proteins with bound polyamines. These proteins are not found in the plasma of healthy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8cc01a001731b4ce0e163d6b6271ee33
http://europepmc.org/abstract/med/3121140
http://europepmc.org/abstract/med/3121140
Publikováno v:
Europe PubMed Central
Bis(7-amino-4-azaheptyl)dimethylsilane is a new type of aliphatic polycation with structural features resembling those of spermine. The elongation to a seven-membered carbon chain in which the central CH2-group was substituted by (CH3)2Si renders the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4ab744db7a5fbdc0f4960859cd321a2d
http://europepmc.org/abstract/med/9051112
http://europepmc.org/abstract/med/9051112
Publikováno v:
Europe PubMed Central
CGP 48664A (2-(4-aminoiminomethyl)-2,3-dihydro-1H-inden-1-ylidene dihydrochloride, CAS 149400-88-4) is a new potent inhibitor of S-adenosylmethionine decarboxylase with antitumor properties. In view of the eminent clinical problems in the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6e9f0c37f01e22da0c0e4947749eca18
http://europepmc.org/abstract/med/8901156
http://europepmc.org/abstract/med/8901156
Autor:
Ferrier J; Clermont Université, Université d'Auvergne, Pharmacologie Fondamentale et Clinique de la Douleur, Clermont-Ferrand, France ; INSERM, U1107 NEURO-DOL, Clermont-Ferrand, France., Bayet-Robert M, Pereira B, Daulhac L, Eschalier A, Pezet D, Moulinoux JP, Balayssac D
Publikováno v:
PloS one [PLoS One] 2013 Oct 30; Vol. 8 (10), pp. e77828. Date of Electronic Publication: 2013 Oct 30 (Print Publication: 2013).
Autor:
Lughezzani G; Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada., Karakiewicz PI, Bigot P, Perrotte P, Crépel M, Rioux-Leclercq N, Catros-Quemener V, Moulinoux JP, Bouet F, Cipolla B, Patard JJ
Publikováno v:
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2010 Jul; Vol. 46 (10), pp. 1927-35. Date of Electronic Publication: 2010 Mar 23.