Altered neurodevelopmental DNA methylation status after fetal growth restriction with brain-sparing

Autor: Anne E Richter, Arend F. Bos, Torsten Plösch, Rikst Nynke Verkaik-Schakel, Elisabeth M. W. Kooi, Iris Bekkering-Bauer, Mariëtte Leeuwerke, Sicco A. Scherjon, Jozien C. Tanis, Caterina M. Bilardo

Publikováno v: Richter, A E, Bekkering-Bauer, I, Verkaik-Schakel, R N, Leeuwerke, M, Tanis, J C, Bilardo, C M, Kooi, E M W, Scherjon, S A, Bos, A F & Plösch, T 2021, ' Altered neurodevelopmental DNA methylation status after fetal growth restriction with brain-sparing ', Journal of Developmental Origins of Health and Disease . https://doi.org/10.1017/S2040174421000374
Journal of developmental origins of health and disease, 13(3), 378-389. Cambridge University Press
Journal of Developmental Origins of Health and Disease. Cambridge University Press

It is under debate how preferential perfusion of the brain (brain-sparing) in fetal growth restriction (FGR) relates to long-term neurodevelopmental outcome. Epigenetic modification of neurotrophic genes by altered fetal oxygenation may be involved.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25255278e56b2e552ccee9cc03079a5b
https://doi.org/10.1017/S2040174421000374

Neonatal Hemoglobin Levels in Preterm Infants Are Associated with Early Neurological Functioning

Autor: Elise A Verhagen, Mirthe J Mebius, Jozien C. Tanis, Arend F. Bos, Willemien S Kalteren, Elisabeth M. W. Kooi

Publikováno v: Neonatology, 118(5), 593-599. KARGER

Background: Neonatal anemia may compromise oxygen transport to the brain. The effects of anemia and cerebral oxygenation on neurological functioning in the early neonatal period are largely unknown. Objective: This study aimed to determine the associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19291279985b6ae68dc07e6db8d47c7e
https://research.rug.nl/en/publications/794530d1-f51b-4f35-a73c-40cccd00290e

Differential placental DNA methylation of VEGFA and LEP in small-for-gestational age fetuses with an abnormal cerebroplacental ratio

Autor: Rikst Nynke Verkaik-Schakel, Arend F. Bos, Sicco A. Scherjon, Jozien C. Tanis, Jasper J. H. Eijsink, Mariëtte Leeuwerke, Iris Bekkering, Caterina M. Bilardo, Torsten Plösch, Mirthe H. Schoots

Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0221972 (2019)
PLoS ONE
PLoS ONE, 14(8):e0221972. Public Library of Science
PLoS ONE, 14(8):e0221972. PUBLIC LIBRARY SCIENCE

BACKGROUND: In Fetal Growth Restriction 'fetal programming' may take place via DNA methylation, which has implications for short-term and long-term health outcomes. Small-for-gestational age fetuses are considered fetal growth restricted, characteriz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7df5695f437a25bb73fb1842f33f6f
https://doaj.org/article/ab3b86b537444d429f40d93c55b19793

Correlation between Doppler flow patterns in growth-restricted fetuses and neonatal circulation

Autor: C. M. Bilardo, Arend F. Bos, M. R. Boelen, L. Casarella, Jozien C. Tanis, D. M. Schmitz, ME van der Laan

Publikováno v: Ultrasound in Obstetrics & Gynecology. 48:210-216

Objectives To investigate whether prenatal Doppler parameters in growth-restricted fetuses are correlated with neonatal circulatory changes. Methods In 43 cases of suspected fetal growth restriction (FGR), serial Doppler measurements of umbilical art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be49837d797efed9b5bd66894ba35f12
https://doi.org/10.1002/uog.15744

Online versus offline spatiotemporal image correlation (STIC) M-mode for the evaluation of cardiac longitudinal annular displacement in fetal growth restriction

Autor: Fatima Crispi, Bart Bijnens, Josep M. Martinez, Jozien C. Tanis, Nuruddin Mohammed, Mar Bennasar, Eduard Gratacós

Publikováno v: Journal of Maternal-Fetal & Neonatal Medicine, 31(14), 1845-1850. Taylor & Francis Ltd

Purpose: Our first aim was to compare online M-mode with offline spatiotemporal image correlation (STIC) M-mode for assessing longitudinal annular displacement (LAD) in growth-restricted fetuses (FGR). Our second aim was to compare LAD measures of FG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0f6d1f099bc4db97caad4ca5452a47
http://hdl.handle.net/10230/48166