Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jozef Zidzik"'
Autor:
Dominika Jarčušková, Ivan Tkáč, Nataša Hlaváčová, Alena Stančáková Yaluri, Miriam Kozárová, Viera Habalová, Lucia Klimčáková, Jozef Židzik, Martin Javorský, Aneta Bednářová
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background There is no doubt that genetic factors have the potential to predict the therapeutic outcomes of antidepressants in patients with major depressive disorder (MDD). This study investigated the association between genetic variants in
Externí odkaz:
https://doaj.org/article/50814b48c82247be8ce6e78e5bfa00da
Autor:
Martin Javorský, Eva Babjaková, Lucia Klimčáková, Zbynek Schroner, Jozef Židzik, Mária Štolfová, Ján Šalagovič, Ivan Tkáč
Publikováno v:
International Journal of Endocrinology, Vol 2013 (2013)
Previous studies showed associations between variants in TCF7L2 gene and the therapeutic response to sulfonylureas. All sulfonylureas stimulate insulin secretion by the closure of ATP-sensitive potassium (KATP) channel. The aim of the present study w
Externí odkaz:
https://doaj.org/article/f8ee17fde8c147c5a382f6cfbc3731b5
Autor:
Jozef Zidzik, Viera Habalova, Martin Javorsky, Ivan Tkáč, Katarina Demkova, Zuzana Malachovska, Miriam Kozarova
Publikováno v:
VASA. Zeitschrift fur Gefasskrankheiten. 47(4)
Abstract. Background: Genome-wide association studies identified several gene variants associated with peripheral arterial disease (PAD). Among them, rs6584389 A>C was significantly associated with PAD defined by decreased ankle-brachial index (ABI).
Autor:
Lucia Klimcakova, Ivana Paranicova, Pavol Joppa, Ruzena Tkacova, Viera Habalova, Jozef Zidzik, Ivana Trojova, Ivan Tkáč
Publikováno v:
4.2 Sleep and Control of Breathing.
Rationale. Genome-wide association studies (GWAS) identified multiple loci associated with blood pressure (BP) control. We evaluated the effects of single nucleotide polymorphisms (SNPs) of JAG1 , GUCY1A3-GUCY 1B3 , SH2B3 , FGF5 , and NPR3-C5orf23 on
Autor:
Eva Babjaková, Ruzena Tkacova, Zbynek Schroner, Lucia Klimcakova, Miriam Kozarova, Ján Šalagovič, Martin Javorsky, Maria Fabianova, Ivan Tkáč, Jozef Zidzik
Publikováno v:
European Journal of Internal Medicine. 23:245-249
Potassium inwardly rectifier 6.2 subunit (Kir6.2) of the ATP-sensitive potassium (K(ATP)) channel encoded by KCNJ11 gene is a therapeutical target for sulfonylureas. KCNJ11 E23K polymorphism was associated with type 2 diabetes in genetic association
Autor:
Ivan Tkáč, Lucia Klimcakova, Ján Šalagovič, Martin Javorsky, Jozef Zidzik, Terezia Hudakova, Miriam Kozarova, Ruzena Tkacova, Martina Dobrikova, Zbynek Schroner
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Scopus-Elsevier
Scopus-Elsevier
Summary Background We aimed to analyse quantitative effects of treatment with sulphonylurea in addition to metformin on parameters of glycemic control in relation to KCNQ1 genotypes, and to identify factors predictive for the response to sulphonylure
Autor:
Martin Javorsky, M. Rudikova, Martina Dobrikova, Ivan Tkáč, Miriam Kozarova, Lucia Klimcakova, Jozef Zidzik, Zbynek Schroner, V. Habalova, Ruzena Tkacova
Publikováno v:
Diabetes, obesitymetabolism. 13(1)
The aim of the present study was to analyse effects of sulphonylurea treatment on parameters of glycaemic control in relation to transcription factor 7-like 2 (TCF7L2) genotypes. In 87 patients with type 2 diabetes who failed to achieve glycaemic con
Autor:
Michal, Mokry, Pavol, Joppa, Eva, Slaba, Jozef, Zidzik, Viera, Habalova, Zuzana, Kluchova, Lydia, Micietova, Eva, Rozborilova, Jan, Salagovic, Ruzena, Tkacova
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 14(8)
The role of the beta2-adrenergic receptor (ADRB2) genotype in patients with chronic obstructive pulmonary disease (COPD) is unclear. In patients with acute exacerbations of COPD (AECOPD), we assessed the role of ADRB2 haplotypes in morning lung funct
Autor:
Peter B. Farmer, Ivan Kalina, Jozef Zidzik, Blanka Binkova, Todor A. Popov, Ivo Solansky, Pavel Rossner, Olena Beskid, Radim J. Sram, Zdik Dusek
Publikováno v:
Mutation research. 620(1-2)
The fluorescence in situ hybridization (FISH) technique with whole chromosome painting for chromosomes #1 and #4 was used to study the impact of air pollution containing higher concentrations of carcinogenic polycyclic aromatic hydrocarbons (c-PAHs)
Autor:
Karolina D. Lyubomirova, Peter B. Farmer, Jozef Zidzik, Radim J. Sram, Alena Milcova, Blanka Binkova, Pavel Rossner, Ivo Solansky
Publikováno v:
Mutation research. 620(1-2)
We analyzed the effect of exposure to carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) in ambient air on the plasma levels of p53 and p21 WAF1 proteins among city policemen, bus drivers and controls in three European cities: Prague (Czech Repub