Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Jozef Mardiak"'
Autor:
Patrik Palacka, Andrea Holíčková, Jan Roška, Peter Makovický, Miroslava Vallová, Csaba Biró, Eveline Órásová, Jana Obertová, Jozef Mardiak, Thomas A. Ward, Karol Kajo, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Cisplatin (CDDP) remains a key agent in the treatment of muscle-infiltrating bladder carcinoma (MIBC). However, a proportion of MIBC patients do not respond to chemotherapy, which may be caused by the increased repair of CDDP-indu
Externí odkaz:
https://doaj.org/article/761780bca58d45ffaf4f2ed1c5328ebb
Autor:
Peter Lesko, Barbora Vlkova, Katarina Kalavska, Valentina De Angelis, Vera Novotna, Jana Obertova, Zuzana Orszaghova, Patrik Palacka, Katarina Rejlekova, Zuzana Sycova-Mila, Boris Kollarik, Ramadan Aziri, Daniel Pindak, Jozef Mardiak, Michal Chovanec, Peter Celec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundTesticular cancer is the most common malignancy among young men. Vitamin D has pluripotent effects on cancer pathogenesis and plays a role in the metastatic cascade. The aim of this study is to analyze plasma vitamin D in association with c
Externí odkaz:
https://doaj.org/article/eb40b8275b794adc92aea21ffd4ad3c6
Autor:
Michal Chovanec, Katarina Kalavska, Jana Obertova, Patrik Palacka, Katarina Rejlekova, Zuzana Sycova-Mila, Zuzana Orszaghova, Peter Lesko, Valentina De Angelis, Lucia Vasilkova, Daniela Svetlovska, Beata Mladosievicova, Jozef Mardiak, Michal Pastorek, Barbora Vlkova, Peter Celec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSurvivors of testicular germ cell tumors (GCT) may suffer from late cognitive impairment. We hypothesized that disruption of intestinal barrier during chemotherapy and/or radiotherapy may be a contributing factor of cognitive dysfunction wi
Externí odkaz:
https://doaj.org/article/abf7e03270314533aff2dabde227fda2
Autor:
Michal Mego, Katarina Rejlekova, Daniela Svetlovska, Vera Miskovska, Ad J.M. Gillis, Valentina De Angelis, Katarina Kalavska, Jana Obertova, Patrik Palacka, Maria Reckova, Zuzana Sycova-Mila, Daniel Pindak, Michal Chovanec, Leendert H.J. Looijenga, Jozef Mardiak
Publikováno v:
European Urology Open Science, Vol 33, Iss , Pp 19-27 (2021)
Background: Germ cell tumors represent highly curable disease even in metastatic stage. However, poor-risk patients with an unfavorable serum tumor marker (STM) decline after the first cycle of chemotherapy represent a subgroup with dismal prognosis,
Externí odkaz:
https://doaj.org/article/d3c43bc015da42a092dcf78191b04e22
Autor:
Michal Mego, Barbora Vlkova, Gabriel Minarik, Zuzana Cierna, Marian Karaba, Juraj Benca, Tatiana Sedlackova, Dana Cholujova, Paulina Gronesova, Katarina Kalavska, Daniel Pindak, Jozef Mardiak, Peter Celec
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCirculating tumor cells (CTCs) contribute to the metastatic cascade and represent an independent survival predictor in breast cancer (BC) patients. Vitamin D has pleiotropic effects, and its low concentrations are associated with breast can
Externí odkaz:
https://doaj.org/article/867b3ca3a243447a8a3e63865a0ced71
Autor:
Katarina Rejlekova, Katarina Kalavska, Marek Makovnik, Nikola Hapakova, Michal Chovanec, Valentina De Angelis, Jana Obertova, Patrik Palacka, Zuzana Sycova-Mila, Jozef Mardiak, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGerm cell tumors (GCTs) represent a highly curable cancer. However, a small proportion of poor-risk patients can develop choriocarcinoma syndrome (CS) connected with acute respiratory distress syndrome (ARDS) with a high mortality rate. Our
Externí odkaz:
https://doaj.org/article/823de7803edb437490c82821e5272339
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The pattern of immune cell distribution in testicular germ cell tumors (GCT) significantly differs from the immune environment in normal testicular tissues. The present study aimed to evaluate the role of different leukocyte subpopulation in GCTs. A
Externí odkaz:
https://doaj.org/article/9c04b63fe92a4f1993d3dd27de6da4ca
Autor:
Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be cau
Externí odkaz:
https://doaj.org/article/a1198c34116345488384869795332127
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Life, Vol 12, Iss 5, p 678 (2022)
The tumor microenvironment (TME) and the host inflammatory response are closely interconnected. The interplay between systemic inflammation and the local immune response may influence tumor development and progression in various types of cancer. The
Externí odkaz:
https://doaj.org/article/367ab3bb9108473ea0b1e0d0af88d0de
Autor:
Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Katarina Kalavska, Katarina Rejlekova, Daniela Svetlovska, Dusan Macak, Stanislav Spanik, Karol Kajo, Pavel Babal, Michal Mego, Jozef Mardiak
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. Methods Sur
Externí odkaz:
https://doaj.org/article/e2bedfd776a24a93b149c36fc239cb18