Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joyner Wong"'
Autor:
Ho, Soo Yei, Wang, Weiling, Ng, Fui Mee, Wong, Yun Xuan, Poh, Zhi Ying, Tan, Sum Wai Eldwin, Ang, Shi Hua, Liew, Si Si, Joyner Wong, Yin Sze, Tan, Yvonne, Poulsen, Anders, Pendharkar, Vishal, Sangthongpitag, Kanda, Manchester, John, Basarab, Gregory, Hill, Jeffrey, Keller, Thomas H., Cherian, Joseph
Publikováno v:
In European Journal of Medicinal Chemistry 5 September 2018 157:610-621
Autor:
John I. Manchester, Vishal Pendharkar, Thomas H. Keller, Yvonne Tan, Shi Hua Ang, Si Si Liew, Sum Wai Eldwin Tan, Zhi Ying Poh, Yin Sze Joyner Wong, Kanda Sangthongpitag, Fui Mee Ng, Weiling Wang, Jeffrey Hill, Joseph Cherian, Yun Xuan Wong, Gregory S. Basarab, Soo Yei Ho, Anders Poulsen
Publikováno v:
European Journal of Medicinal Chemistry. 157:610-621
Even though many GyrB and ParE inhibitors have been reported in the literature, few possess activity against Gram-negative bacteria. This is primarily due to limited permeability across Gram-negative bacterial membrane as well as bacterial efflux mec
Autor:
Hiroshi Hamada, Bruno Reversade, Artina Metoska, Fui Mee Ng, Jeffrey Hill, Patrick Cozzone, Nithya Baburajendran, Hülya Kayserili, Oz Pomp, Nathalie Escande-Beillard, Joyner Wong, Abigail Loh, Kohei Kanata, Sahar N. Saleem, Joanes Grandjean, Yui Hashimoto, E. Beillard, Umut Altunoglu, Hidetaka Shiratori, Maha S. Zaki
Publikováno v:
Neuron, 107, 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Patients lacking PYCR2, a mitochondrial enzyme that synthesizes proline, display postnatal degenerative microcephaly with hypomyelination. Here we report the crystal structure of the PYCR2 apo-enzyme and show that a novel germline p.Gly249Val mutatio