Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joyce van der Heijden"'
Autor:
Jolien Freriksen, Susan Cole, Joyce van der Heijden, Karen R Yeo, Trevor Johnson, Essam Kerwash, Marika de Hoop-Sommen, Rick Greupink, Janet Nooney, Saskia de Wildt, Ping Zhao
Publikováno v:
Gates Open Research, Vol 7 (2023)
Physiologically based pharmacokinetic (PBPK) models represent computational technology to characterize drug behavior within the context of detailed human physiology. Today, PBPK is routinely used in drug development and regulatory approval to support
Externí odkaz:
https://doaj.org/article/428afdfe2659434fa3aede8712f96746
Autor:
Joyce van der Heijden, Jolien Freriksen, Marika de Hoop-Sommen, Rick Greupink, Saskia de Wildt
Publikováno v:
Archives of Disease in Childhood. 108:A4.3-A5
IntroductionMore than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) models are increasingly used to study PK and guide dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf4d84f6db1b7257afc94cdf56ad885
https://doi.org/10.1136/archdischild-2023-esdppp.13
https://doi.org/10.1136/archdischild-2023-esdppp.13