Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joyce Yamashiro"'
Autor:
Lin Lin, Nathanael Kane, Robert E. Reiter, Joyce Yamashiro, Evelyn A. Kono, Nicholas G. Nickols, Naoko Kobayashi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(5)
Purpose: The use of high-dose per fraction radiotherapy delivered as stereotactic body radiotherapy is a standard of care for prostate cancer. It is hypothesized that high-dose radiotherapy may enhance or suppress tumor-reactive immunity. The objecti
Autor:
Ziyue Karen Jiang, Robert E. Reiter, Chun Wang, Mo Zhang, Evelyn A. Kono, Kirstin A. Zettlitz, Naoko Kobayashi, Anna M. Wu, Johnny Guan, Wen-Ting K Tsai, Chau P. Tran, Joyce Yamashiro
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(1)
Purpose: The inability to intraoperatively distinguish primary tumor, as well as lymphatic spread, increases the probability of positive surgical margins, tumor recurrence, and surgical toxicity. The goal of this study was to develop a tumor-specific
Autor:
Robert E. Reiter, D. Seiler, Joyce Yamashiro, Gentao Liu, Junying Zheng, Shunyou Wang, Jiaoti Huang, Gang Zeng
Publikováno v:
The Prostate. 73:1378-1390
BACKGROUND Prostate cancer stem cells (PCSC) offer theoretical explanations to many clinical and biological behaviors of the disease in human. In contrast to approaches of using side populations and cell-surface markers to isolate and characterize th
Autor:
Hiroshi Tanaka, Martin E. Gleave, Ladan Fazli, Steven Horvath, Robert Wada, Robert E. Reiter, Jiaoti Huang, Hideyo Miyazaki, Jaibin An, Zev A. Wainberg, Evelyn A. Kono, Chau P. Tran, Tatsuya Shimomura, Robert L. Vessella, Joyce Yamashiro, Matthew Rettig
Publikováno v:
Nature Medicine. 16:1414-1420
The transition from androgen-dependent to castration-resistant prostate cancer (CRPC) is a lethal event of uncertain molecular etiology. Comparing gene expression in isogenic androgen-dependent and CRPC xenografts, we found a reproducible increase in
Autor:
Evelyn A. Kono, Chun Wang, Robert E. Reiter, Joyce Yamashiro, Kirstin A. Zettlitz, Anna M. Wu, Naoko Kobayashi, Keyu Li
Publikováno v:
Cancer Research. 78:1775-1775
Enzalutamide (ENZ) is an androgen receptor (AR) antagonist that targets various stages of the AR signaling pathway, and approved for the treatment of castration resistant prostate cancer (CRPC). Studies show increased survival in men with metastatic
Publikováno v:
Cancer Research. 78:5901-5901
Neuroendocrine and Small Cell Prostate Cancer (NEPC) is a lethal disease emerging from Castrate Resistant Prostate Cancer (CRPC) after treatment with next-generation anti-androgen therapies such as abiraterone and enzalutamide. The mechanisms by whic
Autor:
Della Z. Hu, Naoko Kobayashi, Evelyn A. Kono, Wang Chun, Anna M. Wu, Kirstin A. Zettlitz, Robert E. Reiter, Joyce Yamashiro
Publikováno v:
Clinical Cancer Research. 24:A52-A52
Introduction: Recent advances improved survival in men with metastatic castration-resistant prostate cancer (CRPC) after chemotherapy when treated with androgen ablation therapies, including the well-known androgen receptor (AR) antagonist enzalutami
Autor:
Robert E. Reiter, Zhennan Gu, Joyce Yamashiro, Frederick J. Dorey, Shintaku Ip, George Thomas, Massimo Loda, Owen N. Witte, Arthur B. Raitano, Jonathan W. Said
Publikováno v:
Oncogene. 19:1288-1296
Prostate stem cell antigen (PSCA) is a recently defined homologue of the Thy-1/Ly-6 family of glycosylphosphatidylinositol (GPI)-anchored cell surface antigens. PSCA mRNA is expressed in the basal cells of normal prostate and in more than 80% of pros
Autor:
Kinga Szigeti, Sazuku Nisitani, Matthew I. Wahl, Tetsuro Watabe, Joyce Yamashiro, Owen N. Witte, Michelle M. Le Beau, George Thomas, Zhennen Gu, Elizabeth M. Davis, Massimo Loda, Robert E. Reiter
Publikováno v:
Proceedings of the National Academy of Sciences. 95:1735-1740
The identification of cell surface antigens is critical to the development of new diagnostic and therapeutic modalities for the management of prostate cancer. Prostate stem cell antigen (PSCA) is a prostate-specific gene with 30% homology to stem cel
Publikováno v:
Experimental Cell Research. 239:169-174
Sodium phenylacetate (NaPA) has been shown to synergize with retinoic acid (RA) in inducing the differentiation of human neuroblastoma cells. Our studies indicated that NaPA can impact on the RA differentiation program by upregulating nuclear retinoi