Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joyce Y. Buikhuisen"'
Autor:
Joyce Y. Buikhuisen, Patricia M. Gomez Barila, Kate Cameron, Saskia J. E. Suijkerbuijk, Cor Lieftink, Simone di Franco, Ana Krotenberg Garcia, Rebeca Uceda Castro, Kristiaan J. Lenos, Lisanne E. Nijman, Arezo Torang, Ciro Longobardi, Joan H. de Jong, Daniëlle Dekker, Giorgio Stassi, Louis Vermeulen, Roderick L. Beijersbergen, Jacco van Rheenen, Stephan Huveneers, Jan Paul Medema
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Colorectal cancer (CRC) can be divided into four consensus molecular subtypes (CMS), each with distinct biological features. CMS4 is associated with epithelial-mesenchymal transition and stromal infiltration (Guinney et al., Nat M
Externí odkaz:
https://doaj.org/article/f5507e6ca1b2488d88586c36a3b6eee2
Autor:
Joyce Y. Buikhuisen, Patricia M. Gomez Barila, Arezo Torang, Daniëlle Dekker, Joan H. de Jong, Kate Cameron, Sara Vitale, Giorgio Stassi, Sander R. van Hooff, Mauro A. A. Castro, Louis Vermeulen, Jan Paul Medema
Publikováno v:
Cancers, Vol 13, Iss 4, p 801 (2021)
Colorectal cancer (CRC) is a heterogeneous disease that can currently be subdivided into four distinct consensus molecular subtypes (CMS) based on gene expression profiling. The CMS4 subtype is marked by high expression of mesenchymal genes and is as
Externí odkaz:
https://doaj.org/article/2426dd91af484d309ec205850f15ba30
Publikováno v:
Oncogenesis, Vol 9, Iss 7, Pp 1-15 (2020)
Oncogenesis
Oncogenesis
Colon cancer inter-tumour heterogeneity is installed on multiple levels, ranging from (epi)genetic driver events to signalling pathway rewiring reflected by differential gene expression patterns. Although the existence of heterogeneity in colon cance
Autor:
Jan Paul Medema, Danielle Dekker, Arezo Torang, Louis Vermeulen, Joan H. de Jong, Sara Vitale, Joyce Y. Buikhuisen, Kate Cameron, Sander R. van Hooff, Patricia M. Gomez Barila, Giorgio Stassi, Mauro A. A. Castro
Publikováno v:
Cancers
Cancers, Vol 13, Iss 801, p 801 (2021)
Cancers, 13(4):801, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 13
Issue 4
Cancers, Vol 13, Iss 801, p 801 (2021)
Cancers, 13(4):801, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 13
Issue 4
Simple Summary Colorectal cancer can be subdivided into four distinct subtypes that are characterised by different clinical features and responses to therapies currently used in the clinic to treat this disease. One of those subtypes, called CMS4, is
Autor:
Pramudita R. Prasetyanti, Ronald van Leersum, Janneke F. Linnekamp, Louis Vermeulen, Evelyn Fessler, Peter Nürnberg, Marek Franitza, Hans Clevers, Laura Rosa Mangiapane, Raju Kandimalla, Kate Cameron, Sander R. van Hooff, Giorgio Stassi, Kelly A S T Lee, Johan H de Jong, Joyce Y. Buikhuisen, Hans M. Rodermond, Xin Wang, Jan Paul Medema, Prashanthi Ramesh, Grehor G W Bochove
Publikováno v:
Cell Death and Differentiation, 25(3), 616-633. Nature Publishing Group
Cell death and differentiation, 25, 616-633. Nature Publishing Group
Cell death and differentiation, 25, 616-633. Nature Publishing Group
Colorectal cancer (CRC) is a highly heterogeneous disease both from a molecular and clinical perspective. Several distinct molecular entities, such as microsatellite instability (MSI), have been defined that make up biologically distinct subgroups wi
Autor:
Xi Chen, Wenjun Guo, Zhenhua Jeremy Wu, Xiaole Shirley Liu, Boon Seng Soh, Joyce Y. Buikhuisen, Bing Lim, Haihui Lu, Brian Bierie, Ferenc Reinhardt, Jordan A. Krall, Wai Leong Tam, Robert A. Weinberg, Myles Brown, Elgene Lim
Publikováno v:
PMC
The epithelial-mesenchymal transition program becomes activated during malignant progression and can enrich for cancer stem cells (CSCs). We report that inhibition of protein kinase C α (PKCα) specifically targets CSCs but has little effect on non-
Autor:
Evelyn Fessler, Selcuk Colak, Steven T. Pals, Kate Cameron, Joan H. de Jong, Jan Paul Medema, Joyce Y. Buikhuisen, Marc J. van de Vijver, Hans M. Rodermond, Rogier Versteeg, Felipe De Sousa E Melo, Pramudita R. Prasetyanti, Chris M. van der Loos, Louis Vermeulen, Evelien Dekker, Jan Koster, Jurriaan B. Tuynman, Dick J. Richel, Saskia P. van den Bergh
Publikováno v:
Cell stem cell, 9(5), 476-485. Cell Press
SummaryGene signatures derived from cancer stem cells (CSCs) predict tumor recurrence for many forms of cancer. Here, we derived a gene signature for colorectal CSCs defined by high Wnt signaling activity, which in agreement with previous observation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477ab95708e1cd219a9630ee6fe63f82
https://pure.amc.nl/en/publications/methylation-of-cancerstemcellassociated-wnt-target-genes-predicts-poor-prognosis-in-colorectal-cancer-patients(1f07307b-7508-4809-81cd-25e8dbc62902).html
https://pure.amc.nl/en/publications/methylation-of-cancerstemcellassociated-wnt-target-genes-predicts-poor-prognosis-in-colorectal-cancer-patients(1f07307b-7508-4809-81cd-25e8dbc62902).html