Výsledky vyhledávání - "Joyce S. Tsuji"

Human biokinetic model for soluble nickel addressing inter-individual variation

Autor: Kenneth T. Bogen, Marina Patriarca, Joyce S. Tsuji, Andrew Taylor, Michael D. Taylor

Publikováno v: Human and Ecological Risk Assessment: An International Journal. 27:2015-2037

Worker-specific Biological Exposure Action Levels (BEALs) for nickel (Ni) exposure are a urinary Ni concentration that reflects a dose that can be experienced on a daily basis without adverse syste...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ae6789762a8f9c541955a21732f1aa8
https://doi.org/10.1080/10807039.2021.1915746

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Autor: Alicia A. Taylor, Joyce S. Tsuji, Margaret E. McArdle, William J. Adams, William L. Goodfellow

Publikováno v: Risk analysis : an official publication of the Society for Risk AnalysisREFERENCES.

The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) database, the authoritative source of U.S. risk assessment toxicity factors, currently lacks an oral reference dose (RfD) for copper. In the absence of such a

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https://pubmed.ncbi.nlm.nih.gov/35194835

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Critical Review of Exposure and Effects: Implications for Setting Regulatory Health Criteria for Ingested Copper

Autor: Alicia A. Taylor, William J. Adams, Michael R. Garry, Margaret E. McArdle, Joyce S. Tsuji, William L. Goodfellow, Charles A. Menzie

Publikováno v: Environmental Management

Decades of study indicate that copper oral exposures are typically not a human health concern. Ingesting high levels of soluble copper salts can cause acute gastrointestinal symptoms and, in uncommon cases, liver toxicity in susceptible individuals w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2d6c966551357fbe4be93411b27dd7
http://europepmc.org/articles/PMC6960211

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Inorganic arsenic: a nongenotoxic threshold carcinogen

Autor: Lora L. Arnold, Samuel M. Cohen, Joyce S. Tsuji

Publikováno v: Current Opinion in Toxicology. 14:8-13

Summary Inorganic arsenic (iA) in the drinking water is a human carcinogen (bladder, lung, and skin). The mode of action involves metabolism to trivalent arsenicals that react with sulfhydryl groups in critical proteins, leading to cytotoxicity with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79b3ae467b50ba0619ecee039b30b9e6
https://doi.org/10.1016/j.cotox.2019.05.002

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Essential concepts for interpreting the dose-response of low-level arsenic exposure in epidemiological studies

Autor: Kristin P. Lennox, Joyce S. Tsuji, Heather N. Watson, Ellen T. Chang

Publikováno v: Toxicology. 457

Scientifically robust selections of epidemiological studies and assessments of the dose-response of inorganic arsenic in the low-dose range must consider key issues specific to arsenic in order to reduce risk of bias. The abundance of toxicological,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f365e59ab59939c300ca1e8d1e7de88
https://pubmed.ncbi.nlm.nih.gov/33905760

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Correction to: Critical Review of Exposure and Effects: Implications for Setting Regulatory Health Criteria for Ingested Copper

Autor: Alicia A. Taylor, Joyce S. Tsuji, Michael R. Garry, Margaret E. McArdle, William L. Goodfellow, William J. Adams, Charles A. Menzie

Publikováno v: Environmental Management. 69:1051-1051

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7af7e7faba40d6e285509014cc25fef9
https://doi.org/10.1007/s00267-022-01618-7

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Utilizing a Combination of TGA and GC-MS to Estimate Health-Based Risks from Off-Gassed Volatile Compounds

Autor: Eric P. Guyer, Joyce S. Tsuji, Michael R. Garry, Steven Valenty, Scott Seidel, Joseph A. Lemberg

Publikováno v: Journal of Failure Analysis and Prevention. 18:246-249

Off-gassed compounds emitted from various materials can, in some instances, present health risks. In order to assess the potential health risks, off-gassed compounds must be identified, quantified, and evaluated relative to known health-based exposur

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https://doi.org/10.1007/s11668-018-0427-3

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Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

Autor: Samuel M. Cohen, P. Robinan Gentry, Ellen T. Chang, Harvey J. Clewell, Joyce S. Tsuji, Paolo Boffetta

The biologic effects of inorganic arsenic predominantly involve reaction of the trivalent forms with sulfhydryl groups in critical proteins in target cells, potentially leading to various toxicologic events including cancer. This mode of action is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c549f326ab5525ba1ad019976d7da4f
http://hdl.handle.net/11585/736921

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Considerations when using longitudinal cohort studies to assess dietary exposure to inorganic arsenic and chronic health outcomes

Autor: Carolyn G. Scrafford, Leila M. Barraj, Joyce S. Tsuji

Publikováno v: Food and Chemical Toxicology. 93:111-118

Dietary arsenic exposure and chronic health outcomes are of interest, due in part to increased awareness and data available on inorganic arsenic levels in some foods. Recent concerns regarding levels of inorganic arsenic, the primary form of arsenic

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