Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joyce Myers"'
Publikováno v:
Educational Studies. 47:38-58
The purpose of this study was to investigate the relationship between early childhood/elementary pre-service teachers’ sense of teaching efficacy and feelings of preparedness and actual performance...
Autor:
Joyce Myers
Publikováno v:
Teaching The ‘Slow’ Learner in The Secondary School ISBN: 9781003174301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::835150d13bea92d162763de54614c628
https://doi.org/10.4324/9781003174301-6
https://doi.org/10.4324/9781003174301-6
Autor:
Theodros Asberom, Peng Wang, William J. Greenlee, Yueqing Hu, Madhu Chintala, Joyce Myers, Yuguang Wang, Ruo Xu, Andrew Stamford, Craig D. Boyle, Dmitri A. Pissarnitski, Stanley Kurowski, Jairam Palamanda, Samuel Chackalamannil, John W. Clader, Subbarao Vemulapalli, Ping Wu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1291-1294
Development of structure–activity relationship of cyclic guanines I lead us to discovery of a potent and selective series of phosphodiesterase 5 inhibitors 52 – 59 (IC 50 =1.3–11.0 nM, PDE6/5=116–600).
Publikováno v:
Biochemical and Biophysical Research Communications. 168:979-986
We have used [3H]N alpha-methylhistamine to characterize H3-binding in the guinea pig brain and to study its tissue distribution. Kinetic and equilibrium binding experiments indicate a single class of high affinity sites in membranes isolated from gu
Autor:
Zhiyong Hu, Madhu Chintala, Jairam Palamanda, Claire M. Lankin, Dmitri A. Pissarnitski, Yan Xia, William J. Greenlee, Yuguang Wang, Samuel Chackalamannil, Ping Wu, Andrew Stamford, Craig D. Boyle, Jeffrey M. Skell, Peng Wang, Stanley Kurowski, Theodros Asberom, Joyce Myers, Ruo Xu, Subbarao Vemulapalli
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(21)
We have discovered potent and selective xanthine PDE5 inhibitors. Compound 25 (PDE5 IC50=0.6 nM, PDE6/PDE5=101) demonstrated similar functional efficacy and PK profile to Sildenafil (PDE5 IC50=3.5 nM, PDE6/PDE5=7).
Publikováno v:
Life sciences. 68(17)
Human, dog and rabbit corpus cavernosum type 5 phosphodiesterases (PDE5) were isolated and their characteristics were compared. The three enzymes showed Km values of 0.8, 2.1 and 2.3 uM, respectively. They exhibited similar pH-dependence with optimal
Autor:
Richard W. Chapman, Michael Minnicozzi, William Kreutner, Angela Falcone, Joyce Myers, Peng Wang, Howard Jones, Ted T. Kung, Charles G. Garlisi, M. Motasim Billah, D. Stelts, Shelby P. Umland, Robert W. Egan, Yvette Crawley
Publikováno v:
American journal of respiratory cell and molecular biology. 20(2)
The maturation of eosinophils in bone marrow, their migration to pulmonary tissue, and their subsequent degranulation and release of toxic granule proteins contributes to the pathophysiology observed in asthma. Interleukin-5 (IL-5) is essential for t
Autor:
Boonlert Cheewatrakoolpong, Ping Wu, Joyce Myers, Peng Wang, M. Motasim Billah, Robert W. Egan
Publikováno v:
Biochemical and biophysical research communications. 234(2)
Although four members (A, B, C, and D) of the cAMP-specific phosphodiesterase (PDE4) family have been cloned by different groups, no study comparing the characteristics of purified human PDE4 subtypes has been published. In this study, we have expres
The supernatant fraction from lysed human eosinophils, when separated by gel-filtration chromatography, contains a protein with lysophospholipase activity of approximate molecular mass 74 kDa. This mass differs substantially from the 17 kDa of a prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6b7a02464c8b49f9b0c876c844f565
https://europepmc.org/articles/PMC1135811/
https://europepmc.org/articles/PMC1135811/
Publikováno v:
European journal of pharmacology. 210(1)
The distribution of high affinity histamine H 3 receptors in various tissues from guinea pig has been determined using [ 3 H]N α -methylhistamine binding. In the course of those studies, it was observed that the pituitary gland contains H 3 receptor