Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joyce Moffat"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 401:27-32
Ataxia telangiectasia (AT) cells display a profound sensitivity to ionizing radiation, exhibiting more frequent chromosomal breaks, increased micronuclei formation and abnormal DNA repair kinetics following exposure. Despite the recent cloning of the
Autor:
John Curry, Magomed Khaidakov, Gwyn Bebb, Barry W. Glickman, Alan Mortimer, Daniel Young, Joyce Moffat
Publikováno v:
Human Mutation. 9:445-451
The relative contribution of both genetic and environmental factors to spontaneous mutation frequency in humans is unknown. We have investigated the contribution of genetic factors to this phenomenon by determining the in vivo mutant frequency at the
Autor:
Mohammed Khaidakov, Johan G. de Boer, Aparecido Divino da Cruz, Joyce Moffat, John Curry, Barry W. Glickman, Wolfgang C. Kusser, Larissa Karnaoukhova
Publikováno v:
Journal of Cellular Biochemistry. 63:99-107
Mutational specificity describes the composite of all of the genetic alterations in a collection of mutations arising from a specific treatment. The information includes not only the nature of the genetic change (e.g., a base substitution or a frames
Autor:
Sian D. Spacey, Kirsten A. Skov, Gary de Jong, Barry W. Glickman, Pamela J. Warrington, Zhe Yu, Karen A. Gelmon, Joyce Moffat, D.Gwyn Bebb
Publikováno v:
Mutation research. 476(1-2)
Recent reports suggest that the radiation-induced, p53-dependent, apoptotic response is aberrant in ataxia telangiectasia (AT) cells. We investigated the possibility that an aberrant apoptotic response to ionizing radiation may also be the characteri