Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Joyce Man Fong, Lee"'
Autor:
Yu-Man Tsui, Daniel Wai-Hung Ho, Karen Man-Fong Sze, Joyce Man-Fong Lee, Eva Lee, Qingyang Zhang, Gary Cheuk-Hang Cheung, Chung-Ngai Tang, Victor Wai-Lun Tang, Elaine Tin-Yan Cheung, Irene Lai-Oi Lo, Albert Chi-Yan Chan, Tan-To Cheung, Irene Oi-Lin Ng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 3, Pp 101358- (2024)
Background & Aims: Hepatocellular carcinoma (HCC) is a heterogeneous cancer with varying levels of liver tumor initiating or cancer stem cells in the tumors. We aimed to investigate the expression of different liver cancer stem cell (LCSC) markers in
Externí odkaz:
https://doaj.org/article/d5a5192378254ec88c9bf87ad3bb3e2d
Autor:
Charles Shing Kam, Daniel Wai-Hung Ho, Vanessa Sheung-In Ming, Lu Tian, Karen Man-Fong Sze, Vanilla Xin Zhang, Yu-Man Tsui, Abdullah Husain, Joyce Man-Fong Lee, Carmen Chak-Lui Wong, Albert Chi-Yan Chan, Tan-To Cheung, Lo-Kong Chan, Irene Oi-Lin Ng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1325-1350 (2023)
Background & Aims: Metabolic reprogramming is recognized as a cancer hallmark intimately linked to tumor hypoxia, which supports rapid tumor growth and mitigates the consequential oxidative stress. Phosphofructokinase-fructose bisphosphatase (PFKFB)
Externí odkaz:
https://doaj.org/article/4caaf380883542f299e658fda3245384
Autor:
Daniel Wai-Hung Ho, Yu-Man Tsui, Lo-Kong Chan, Karen Man-Fong Sze, Xin Zhang, Jacinth Wing-Sum Cheu, Yung-Tuen Chiu, Joyce Man-Fong Lee, Albert Chi-Yan Chan, Elaine Tin-Yan Cheung, Derek Tsz-Wai Yau, Nam-Hung Chia, Irene Lai-Oi Lo, Pak-Chung Sham, Tan-To Cheung, Carmen Chak-Lui Wong, Irene Oi-Lin Ng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Different cells of the tumour microenvironment in HBV-associated human hepatocellular carcinoma (HCC) interact to promote tumour immunity. Here the authors use single cell RNA sequencing to identify TIGIT-NECTIN2 as a pathway by which tumour-associat
Externí odkaz:
https://doaj.org/article/f985f3f45e114476aff8ed39645b53e3
Autor:
Tan-To Cheung, Daniel Wai-Hung Ho, Shirley Xueying Lyu, Qingyang Zhang, Yu-Man Tsui, Tiffany Ching-Yun Yu, Karen Man-Fong Sze, Joyce Man-Fong Lee, Vince Wing-hang Lau, Edward Yin-Lun Chu, Simon Hing-Yin Tsang, Wong-Hoi She, Roland Ching-Yu Leung, Thomas Chung-Cheung Yau, Irene Oi-Lin Ng
Publikováno v:
Liver Cancer, Pp 1-1 (2023)
Introduction: Immunotherapy has resulted in pathologic responses in hepatocellular carcinoma (HCC), but the benefits and molecular mechanisms of neoadjuvant immune checkpoint blockade are largely unknown. Methods: In this study, we evaluated the effi
Externí odkaz:
https://doaj.org/article/9220633b483e47fb8ec0cfec18ef0f8a
Autor:
Abdullah Husain, Yung-Tuen Chiu, Karen Man-Fong Sze, Daniel Wai-Hung Ho, Yu-Man Tsui, Eliana Mary Senires Suarez, Vanilla Xin Zhang, Lo-Kong Chan, Eva Lee, Joyce Man-Fong Lee, Tan-To Cheung, Carmen Chak-Lui Wong, Clive Yik-Sham Chung, Irene Oi-Lin Ng
Publikováno v:
Journal of Hepatology. 77:383-396
The highly proliferative nature of hepatocellular carcinoma (HCC) frequently results in a hypoxic intratumoural microenvironment, which creates a therapeutic challenge owing to a lack of mechanistic understanding of the phenomenon. We aimed to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc150c3be83a1e8d8b1a5670db6c538e
https://doi.org/10.1016/j.jhep.2022.02.018
https://doi.org/10.1016/j.jhep.2022.02.018
Autor:
Yung-Tuen Chiu, Husain, Abdullah, Karen Man-Fong Sze, Daniel Wai-Hung Ho, Suarez, Eliana Mary Senires, Xia Wang, Lee, Eva, Hoi-Tang Ma, Joyce Man-Fong Lee, Lo-Kong Chan, Irene Oi-Lin Ng
Publikováno v:
Hepatology (02709139); Nov2023, Vol. 78 Issue 5, p1368-1383, 16p
Autor:
Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesize
Externí odkaz:
https://doaj.org/article/3cdc6d5ccfb249248e8b45a87e42a838
Autor:
Yick-Pang Ching, Irene Oi-Lin Ng, D. Grahame Hardie, Joyce Man-Fong Lee, Veronica Yee-Law Leong, Heong-Fai Liu, Edith Yuk-Ting Tse, Leo Lap-Yan Wong, Chi-Wai Lee
PDF file - 431K, AMPK activator inhibited HepG2 cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af7cf158bf8e201b576f2a6981bd37a
https://doi.org/10.1158/0008-5472.22393460.v1
https://doi.org/10.1158/0008-5472.22393460.v1
Autor:
Yick-Pang Ching, Irene Oi-Lin Ng, Tai-On Yau, Joyce Man-Fong Lee, Veronica Yee-Law Leong, Mandy Man-Lok Chan, Grace Wing-Yan Mak
Supplementary Figure 3 from Overexpression of a Novel Activator of PAK4, the CDK5 Kinase–Associated Protein CDK5RAP3, Promotes Hepatocellular Carcinoma Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb55bef339d79d19723e467d13cdf01
https://doi.org/10.1158/0008-5472.22390485
https://doi.org/10.1158/0008-5472.22390485
Hepatocarcinogenesis is a multistep process, but systematic analysis using a genetic or molecular approach to accurately delineate the different stages of hepatocellular carcinoma (HCC) development is scarce. In this study, we used genome-wide allelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::923b371516e6bd7867e81c9f7888c993
https://doi.org/10.1158/0008-5472.c.6497883
https://doi.org/10.1158/0008-5472.c.6497883