Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joyce M. Hotz"'
Autor:
Anthony S Basile, Reginald L. Dean, Marc Blaustein, Raymond T. Bartus, Dwaine F. Emerich, Brigido Perdomo, Joyce M. Hotz
Publikováno v:
Neuropsychopharmacology. 28:1973-1982
While oral naltrexone is effective in treating alcohol and opiate dependencies, poor patient adherence and widely fluctuating plasma levels limit its efficacy. To overcome these problems, an extended-release formulation of naltrexone (Vivitrex) was d
Autor:
Joyce M. Hotz, Robert T. Wilder, Megumi Uezono, Joanne M. Curley, Jenny Castillo, Charles B. Berde, Joseph Tigner, Mark Chasin, Robert Langer
Publikováno v:
Anesthesiology. 85:1157-1166
Background Previous work showed that incorporation of dexamethasone (0.05 weight/weight percentage) into bupivacaine microspheres prolonged blockade by eight to 13 times compared with that produced by bupivacaine microspheres alone. The determinants
Autor:
Sonia Hernandez, Megumi Uezono, Jenny Castillo, Charles B. Berde, Jeong-Ok Lim, Mark Chasin, Robert Langer, Joseph Tigner, Joyce M. Hotz, Joanne M. Curley
Publikováno v:
Anesthesiology. 84:1401-1410
Background Biodegradable microspheres are a useful method of drug delivery because they are both injectable and biodegradable, eliminating the need for surgical implantation or removal. Previous work has characterized implantable preparations of loca