Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Joyce K. Thompson"'
Autor:
Nneka E. Mbah, Amy L. Myers, Peter Sajjakulnukit, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Heather Giza, Derek Dang, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zhu, Megan Radyk, Brooke Lavoie, Viveka Nand Yadav, Imhoi Koo, Andrew D. Patterson, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract H3K27M diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), exhibit cellular heterogeneity comprising less-differentiated oligodendrocyte precursors (OPC)-like stem cells and more differentiated astrocyte (AC)-l
Externí odkaz:
https://doaj.org/article/b60128e341cf4e8c9deb69669f6c0187
Autor:
Joyce K. Thompson, Filip Bednar
Publikováno v:
Epigenomes, Vol 5, Iss 4, p 20 (2021)
Pancreatic cancer is a molecularly heterogeneous disease. Epigenetic changes and epigenetic regulatory mechanisms underlie at least some of this heterogeneity and contribute to the evolution of aggressive tumor biology in patients and the tumor’s i
Externí odkaz:
https://doaj.org/article/2202428a78e545d7a1726836017a60a4
Autor:
Arti Shukla, Mutlay Sayan, Catherine M. Westbom, Stacie L. Beuschel, Maximilian B. MacPherson, Joyce K. Thompson, Jill M. Miller
PDF file - 62K, Supplementary Figure 1. Curcumin in combination with asbestos resulted in a synergistic effect on NLRP3 and pro-IL-1beta priming in human mesothelial cells. LP9 cells pretreated with curcumin (Cur 10 microM for 24-48 h) and exposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b9abc35cb538d2d616649e11796be5
https://doi.org/10.1158/1940-6207.22525680.v1
https://doi.org/10.1158/1940-6207.22525680.v1
Autor:
Arti Shukla, Mutlay Sayan, Catherine M. Westbom, Stacie L. Beuschel, Maximilian B. MacPherson, Joyce K. Thompson, Jill M. Miller
PDF file - 61K, Supplementary Figure 2. Curcumin treatment did not reduce MM tumor burden. (A) Allograft model comparing gavage administered curcumin to control group. (B) Allograft model comparing IP administered curcumin to control, cisplatin only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b3da5ee09cc688d6de5179c7699065
https://doi.org/10.1158/1940-6207.22525677.v1
https://doi.org/10.1158/1940-6207.22525677.v1
Autor:
Arti Shukla, Mutlay Sayan, Catherine M. Westbom, Stacie L. Beuschel, Maximilian B. MacPherson, Joyce K. Thompson, Jill M. Miller
Inflammation is a key mediator in the development of malignant mesothelioma, which has a dismal prognosis and poor therapeutic strategies. Curcumin, a naturally occurring polyphenol in turmeric, has been shown to possess anticarcinogenic properties t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a6f978e540aa540c7640d8e82cfd38
https://doi.org/10.1158/1940-6207.c.6544854
https://doi.org/10.1158/1940-6207.c.6544854
Autor:
Nneka E. Mbah, Amy L. Myers, Chan Chung, Joyce K. Thompson, Hanna S. Hong, Peter Sajjakulnukit, Zeribe C. Nwosu, Mengrou Shan, Stefan R. Sweha, Daniella D. Maydan, Brandon Chen, Li Zhang, Brian Magnuson, Zirui Zui, Daniel R. Wahl, Luigi Franchi, Sameer Agnihotri, Carl J. Koschmann, Sriram Venneti, Costas A. Lyssiotis
H3K27M diffuse intrinsic pontine gliomas (DIPG) exhibit cellular heterogeneity comprising less-differentiated, stem-like glioma cells that resemble oligodendrocyte precursors (OPC) and more differentiated astrocyte (AC)-like cells. H3K27M DIPG stem-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e09f2bbf821cb523eaab86fc14098b1
https://doi.org/10.1101/2022.03.01.482555
https://doi.org/10.1101/2022.03.01.482555
Autor:
Catherine Westbom, Joyce K Thompson, Alan Leggett, Maximilian MacPherson, Stacie Beuschel, Harvey Pass, Pamela Vacek, Arti Shukla
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145404 (2015)
Malignant mesothelioma (MM) is a fatal disease in dire need of therapy. The role of inflammasomes in cancer is not very well studied, however, literature supports both pro-and anti-tumorigenic effects of inflammasomes on cancer depending upon the typ
Externí odkaz:
https://doaj.org/article/d81fd22a68824aeaa41d6fc6aab90e2a
Publikováno v:
Cancer Research. 82:A070-A070
The five-year survival rate of pancreatic ductal adenocarcinoma (PDAC) is currently 11% [CP1] and by 2030 PDAC is expected to become the second leading cause of cancer related death. Understanding PDAC initiation and maintenance is important for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593c93d4d284b97df5eacafceebb7214
https://doi.org/10.1158/1538-7445.panca22-a070
https://doi.org/10.1158/1538-7445.panca22-a070
Autor:
Costas A. Lyssiotis, Filip Bednar, Timothy L. Frankel, Joyce K. Thompson, M. Perusina Lanfranca, B. Levi, Christopher J. Halbrook
Publikováno v:
Semin Cancer Biol
Pancreatic Cancer (PDA) is an aggressive malignancy characterized by early spread and a high mortality. Current studies suggest that a subpopulation of cells exist within tumors, cancer stem cell (CSC), which are capable of self-renewal and give rise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f191f0580066b79e07f0c144535f7ed1
https://doi.org/10.1016/j.semcancer.2018.09.008
https://doi.org/10.1016/j.semcancer.2018.09.008
Autor:
Filip Bednar, Joyce K. Thompson
Publikováno v:
Epigenomes
Epigenomes, Vol 5, Iss 20, p 20 (2021)
Epigenomes, Vol 5, Iss 20, p 20 (2021)
Pancreatic cancer is a molecularly heterogeneous disease. Epigenetic changes and epigenetic regulatory mechanisms underlie at least some of this heterogeneity and contribute to the evolution of aggressive tumor biology in patients and the tumor’s i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10b8edebd6de107df2f56d606d89e48
https://pubmed.ncbi.nlm.nih.gov/34968245
https://pubmed.ncbi.nlm.nih.gov/34968245