Zobrazeno 1 - 10
of 1 756
pro vyhledávání: '"Joyce F"'
Autor:
Joyce F. Benenson, Henry Markovits
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Every human and non-human animal must make tradeoffs in investments in terms of time, energy, and resources. The aim of this study was to extrapolate from the types of investments in survival and reproduction that non-human animals make and
Externí odkaz:
https://doaj.org/article/280e5f036a3c4542a007974613baa251
Autor:
Panagiotis A. Konstantinopoulos, Niya Xiong, Carolyn Krasner, Joyce F. Liu, Hannah Sawyer, Madeline Polak, Hope Needham, Megan Geddes, Lani Koppermann, Meghan Shea, Cesar Castro, Su-Chun Cheng, Ursula A. Matulonis, Elizabeth K. Lee
Publikováno v:
Gynecologic Oncology Reports, Vol 52, Iss , Pp 101348- (2024)
Several lines of preclinical evidence indicate that combining PI3K and CDK4/6 inhibitors may further enhance the efficacy of hormonal therapy by overcoming de novo and acquired resistance to PI3K and CDK4/6 blockade. We evaluated the combination of a
Externí odkaz:
https://doaj.org/article/a58a03d3330d4b9d9bd8d84d99a74acc
Autor:
Joyce F. Benenson, Henry Markovits
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Human males are considered to be more competitive than females. However, females must also compete for resources necessary for their own and their offsprings’ survival. Since females use more indirect forms of competition than males, compa
Externí odkaz:
https://doaj.org/article/e001233553e94ead8f68c99a83dac9b3
Autor:
Douglas C. Brandão, Paula M. A. P. Lima, Isabella C. Martins, Carina S. Cordeiro, Antonielle O. Cordeiro, Lara Vecchi, Joyce F. C. Guerra, Priscila C. Orsolin, Matheus C. Gazolla, Danilo S. Costa, Ademar A. da Silva Filho, Thaise G. Araújo
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Breast Cancer (BC) is the most common cancer in women worldwide and, although 70% of patients are responsive to selective Estrogen Receptor (ER) modulators such as Tamoxifen (Tam), patients’ survival is comprised by resistance t
Externí odkaz:
https://doaj.org/article/bcf068d9d41b43ce843be7e4281baab5
Autor:
Changli Qian, Gordon J Freeman, Tao Jiang, Ursula Matulonis, Ziying Lin, Hye-Jung Kim, Anniina Färkkilä, Hua Yu, Xin Cheng, Antons Martincuks, Joyce F Liu, Qiwei Wang, Liya Ding, Michael J Kearns, Shaozhen Xie, Inga-Maria Launonen, Thomas M Roberts, Jean J Zhao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Poly (ADP-ribose) polymerase (PARP) inhibition (PARPi) has demonstrated potent therapeutic efficacy in patients with BRCA-mutant ovarian cancer. However, acquired resistance to PARPi remains a major challenge in the clinic.Methods PARPi-re
Externí odkaz:
https://doaj.org/article/84e48eba52e74658abc61bd3c1ea75b9
Autor:
Christiana Smith, Angela J Fought, Joyce F Sung, Jennifer R McKinney, Torri D Metz, Kirk B Fetters, Sarah Lazarus, Shannon Capraro, Emily Barr, Carrie Glenny, Jenna Buehler, Adriana Weinberg, CHIP Perinatal Medical Team
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0276473 (2023)
BackgroundAntiretroviral therapy (ART) decreases perinatal HIV transmission, but concerns exist regarding maternal and infant safety. We compared the incidence of congenital malformations and other adverse outcomes in pregnancies exposed to integrase
Externí odkaz:
https://doaj.org/article/ea93f8176ce4414380cc4faaa78ef8d1
Autor:
Panagiotis A. Konstantinopoulos, Alexandre André B. A. da Costa, Doga Gulhan, Elizabeth K. Lee, Su-Chun Cheng, Andrea E. Wahner Hendrickson, Bose Kochupurakkal, David L. Kolin, Elise C. Kohn, Joyce F. Liu, Elizabeth H. Stover, Jennifer Curtis, Nabihah Tayob, Madeline Polak, Dipanjan Chowdhury, Ursula A. Matulonis, Anniina Färkkilä, Alan D. D’Andrea, Geoffrey I. Shapiro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
A randomized phase 2 study recently showed that the addition of ATR inhibitor berzosertib to gemcitabine improved PFS compared to gemcitabine alone in patients with ovarian cancer. In this preplanned exploratory study, the authors demonstrate that a
Externí odkaz:
https://doaj.org/article/47ca4fa1fe9849e2a78a9dcd5d68a796
Autor:
Rebecca L. Porter, Siyu Sun, Micayla N. Flores, Emily Berzolla, Eunae You, Ildiko E. Phillips, Neelima KC, Niyati Desai, Eric C. Tai, Annamaria Szabolcs, Evan R. Lang, Amaya Pankaj, Michael J. Raabe, Vishal Thapar, Katherine H. Xu, Linda T. Nieman, Daniel C. Rabe, David L. Kolin, Elizabeth H. Stover, David Pepin, Shannon L. Stott, Vikram Deshpande, Joyce F. Liu, Alexander Solovyov, Ursula A. Matulonis, Benjamin D. Greenbaum, David T. Ting
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Aberrant expression of viral-like repeat elements is a common feature of epithelial cancers, and the substantial diversity of repeat species provides a distinct view of the cancer transcriptome. Repeatome profiling across ovarian, pancreatic, and col
Externí odkaz:
https://doaj.org/article/3ee791906f1046c18bf708762dc93b36
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Hundreds of studies find that girls and women report feeling greater empathy than boys and men in response to adverse events befalling others. Despite this, few non-self-report measures demonstrate similar sex differences. This produces the
Externí odkaz:
https://doaj.org/article/42ef3ba238c54d18990966808fd04cc8
Autor:
Elizabeth H. Stover, Niya Xiong, Andrea P. Myers, Nabihah Tayob, Victoria Engvold, Madeline Polak, Russell R. Broaddus, Vicky Makker, Ronny Drapkin, Joyce F. Liu, Neil S. Horowitz, Funda Meric-Bernstam, Carol Aghajanian, Robert L. Coleman, Gordon B. Mills, Lewis C. Cantley, Ursula A. Matulonis, Shannon N. Westin, Panagiotis A. Konstantinopoulos
Publikováno v:
Gynecologic Oncology Reports, Vol 40, Iss , Pp 100974- (2022)
Uterine serous carcinoma (USC) is an uncommon subtype of endometrial cancer with a poor prognosis. USCs have genomic alterations in the PI3K pathway. A prior phase II study of AKT inhibitor MK-2206 (an allosteric AKT inhibitor, primarily affecting AK
Externí odkaz:
https://doaj.org/article/9a6dad8bf1b54f1fada0cfe8b5c09232