Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joyce E. M. van der Heijden"'
Autor:
Joyce E. M. van der Heijden, Marika de Hoop-Sommen, Noa Hoevenaars, Jolien J. M. Freriksen, Koen Joosten, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionCritically ill patients show large variability in drug disposition due to e.g., age, size, disease and treatment modalities. Physiologically-based pharmacokinetic (PBPK) models can be used to design individualized dosing regimens taking t
Externí odkaz:
https://doaj.org/article/171193c1949d4eec9eea2f643a4373e1
Autor:
Marika A. de Hoop-Sommen, Joyce E. M. van der Heijden, Jolien J. M. Freriksen, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionModeling and simulation can support dosing recommendations for clinical practice, but a simple framework is missing. In this proof-of-concept study, we aimed to develop neonatal and infant gentamicin dosing guidelines, supported by a prag
Externí odkaz:
https://doaj.org/article/b9186a5e5a144cfead80e41d4eccd928
Autor:
Tom G. Jacobs, Marika A. de Hoop-Sommen, Thomas Nieuwenstein, Joyce E. M. van der Heijden, Saskia N. de Wildt, David M. Burger, Angela Colbers, Jolien J. M. Freriksen
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1424 (2023)
Dose recommendations for lamivudine or emtricitabine in children with HIV and chronic kidney disease (CKD) are absent or not supported by clinical data. Physiologically based pharmacokinetic (PBPK) models have the potential to facilitate dose selecti
Externí odkaz:
https://doaj.org/article/f0e923f5f4f04bd49f39e94d8c77f92b
Autor:
Joyce E. M. van der Heijden, Jolien J. M. Freriksen, Marika A. de Hoop-Sommen, Lianne P. M. van Bussel, Sander H. P. Driessen, Anne E. M. Orlebeke, Laurens F. M. Verscheijden, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Clinical Pharmacokinetics, 61(12), 1705-1717. Adis
Clinical Pharmacokinetics, 61, 1705-1717
Clinical Pharmacokinetics, 61, 12, pp. 1705-1717
Clinical Pharmacokinetics, 61, 1705-1717
Clinical Pharmacokinetics, 61, 12, pp. 1705-1717
Contains fulltext : 287165.pdf (Publisher’s version ) (Open Access) BACKGROUND AND OBJECTIVE: More than half of all drugs are still prescribed off-label to children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for many
Autor:
Jolien J. M. Freriksen, Joyce E. M. van der Heijden, Marika A. de Hoop-Sommen, Rick Greupink, Saskia N. de Wildt
Publikováno v:
Paediatric Drugs, 25, 1, pp. 5-11
Paediatric Drugs, 25, 5-11
Paediatric Drugs, 25(1), 5-11. Adis
Paediatric Drugs, 25, 5-11
Paediatric Drugs, 25(1), 5-11. Adis
Contains fulltext : 291086.pdf (Publisher’s version ) (Open Access) Physiologically based pharmacokinetic (PBPK) modeling can be an attractive tool to increase the evidence base of pediatric drug dosing recommendations by making optimal use of exis
Publikováno v:
Clinical toxicology (Philadelphia, Pa.). 60(11)
Introduction: The annual number of patients > 65 years old about whom the Dutch Poisons Information Center (DPIC) was consulted has more than doubled in the last decade. We aimed to gain insight in the type and circumstances of exposures reported to