Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joyce B. Shepard"'
Autor:
Alan J Weaver, Joyce B Shepard, Royce A Wilkinson, Robert L Watkins, Sarah K Walton, Amanda R Radke, Thomas J Wright, Milat B Awel, Catherine Cooper, Elizabeth Erikson, Mohamed E Labib, Jovanka M Voyich, Martin Teintze
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97742 (2014)
This study investigated the potential antibacterial activity of three series of compounds synthesized from 12 linear and branched polyamines with 2-8 amino groups, which were substituted to produce the corresponding guanides, biguanides, or phenylgua
Externí odkaz:
https://doaj.org/article/53d2d2f8735f48b699c29354e3885d2f
Autor:
Joyce B. Shepard, Alan J. Weaver, Kejing Song, Mohamed E. Labib, Martin Teintze, Seth H. Pincus, Royce A. Wilkinson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2197-2201
The G-protein coupled receptor CXCR4 is a co-receptor for HIV-1 infection and is involved in signaling cell migration and proliferation. In a previous study of non-peptide, guanide-based CXCR4-binding compounds, spermine and spermidine phenylguanides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd4c8713d5f81277e073e10d664cb2a
https://doi.org/10.1016/j.bmcl.2013.01.107
https://doi.org/10.1016/j.bmcl.2013.01.107
Autor:
Joyce B. Shepard, Sarah K. Walton, Edward P. Bergin, Mohamed E. Labib, Martin Teintze, Royce A. Wilkinson, Seth H. Pincus
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:255-263
The G-protein-coupled receptor CXCR4 acts as a coreceptor for human immunodeficiency virus type 1 (HIV-1) infection, as well as being involved in signaling cell migration and proliferation. Compounds that block CXCR4 interactions have potential uses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e59e28bb511f66dd2d6a2e3a955f79
https://doi.org/10.1128/aac.00709-10
https://doi.org/10.1128/aac.00709-10
Publikováno v:
Anti-cancer drugs. 25(1)
CXCR4 has been shown to be overexpressed on breast cancer cells including the human MDA-MB-231 cell line. Cancer cells overexpressing the CXCR4 receptor are capable of undergoing metastasis to organs expressing high levels of CXCL12. We have synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2f2b73c1ad06c9d974cecbdb74866e
https://pubmed.ncbi.nlm.nih.gov/24045366
https://pubmed.ncbi.nlm.nih.gov/24045366
Publikováno v:
SPIE Proceedings.
Synthesis of new PDT triads that incorporate a tumor-killing porphyrin with large two-photon cross-section for 150 fs laser pulses (2000 GM) in the Near-infrared (NIR) at 840 nm, a NIR imaging agent, and a small peptide that targets over-expressed EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d7b8681a30c1371e29f4a7964cadbfd
https://doi.org/10.1117/12.909640
https://doi.org/10.1117/12.909640