Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joyce A.V. Er"'
Inhibitors of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH1) can control endogenous nitric oxide production. A time-dependent covalent inactivator of DDAH1, N(5)-(1-imino-2-chloroethyl)-l-ornithine (K(I) = 1.3 μM, k(inact) = 0.34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c20883ba51e866ad8f4b20a7807d66
https://europepmc.org/articles/PMC6074031/
https://europepmc.org/articles/PMC6074031/
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(15)
We have investigated 4-halopyridines as selective, tunable, and switchable covalent protein modifiers for use in the development of chemical probes. Nonenzymatic reactivity of 4-chloropyridine with amino acids and thiols was ranked with respect to co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf781cfa45a734306891204dc4187aa
https://pubmed.ncbi.nlm.nih.gov/28470883
https://pubmed.ncbi.nlm.nih.gov/28470883
Autor:
Christopher L. Schardon, Yun Wang, Abdul M. Gabisi, Arturo J. Cardounel, Walter Fast, Suhendan Ekmekcioglu, Shougang Hu, Gayle Burstein, Arthur J. Pope, Joyce A.V. Er
Publikováno v:
ChemMedChem. 9:792-797
Inhibitors of the human enzyme dimethylarginine dimethylaminohydrolase-1 (DDAH-1) can raise endogenous levels of asymmetric dimethylarginine (ADMA) and lead to a subsequent inhibition of nitric oxide synthesis. Herein, N5-(1-imino-2-chloroethyl)-L-or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544f39a32ac46c3d07aeb747e89e56c8
https://doi.org/10.1002/cmdc.201300557
https://doi.org/10.1002/cmdc.201300557
Autor:
Eric J. Moorhead, Andrew G. Tennyson, Brian L. Madison, Vincent M. Lynch, Joyce A.V. Er, Christopher W. Bielawski
Publikováno v:
European Journal of Organic Chemistry. 2010:6277-6282
Reaction of 1,3-dimesitylimidazolylidene (1) with p-functionalized phenyl azides 2 (a: H, b: OCH 3 , c: NO 2 ) afforded the respective imidazolylidene-triazenes 3 in good yields (65-99 %). Subsequent treatment with methyl iodide produced the correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb0590e5f6256f077818c2cc3d25fc9b
https://doi.org/10.1002/ejoc.201000939
https://doi.org/10.1002/ejoc.201000939
Autor:
Joyce A.V. Er, Andrew G. Tennyson, Justin W. Kamplain, Vincent M. Lynch, Christopher W. Bielawski
Publikováno v:
European Journal of Inorganic Chemistry. 2009:1729-1738
A new, high-yielding synthesis of 3,3′,4,4′-tetrachlorobiphenyl was developed, facilitating access to a new family of fluorescent 5,5′-bibenzimidazolium salts bearing phenyl or bulky tertiary alkyl N-substituents. Deprotonation of these salts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b79d991ae141db2d283160ccc1ea2c01
https://doi.org/10.1002/ejic.200801188
https://doi.org/10.1002/ejic.200801188
Autor:
Joyce A.V. Er, Dimitri M. Khramov, Peter D. Vu, Vincent M. Lynch, Christopher W. Bielawski, Evelyn L. Rosen
Publikováno v:
Tetrahedron. 64:6853-6862
The effect of tuning the electronic properties of N-heterocyclic carbene (NHC) ligands was evaluated in multiple, mechanistically distinct, metal-mediated reactions. Hydroboration and Heck reactions, catalyzed by Rh–NHC and Pd–NHC complexes, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05e65b6ee44b9e7883fed18c6b517f7
https://doi.org/10.1016/j.tet.2008.04.030
https://doi.org/10.1016/j.tet.2008.04.030