Zobrazeno 1 - 10 of 218 pro vyhledávání: '"Joyce A, O'Shaughnessy"'
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Akademický článek
Targeting HER2/HER3 co‐mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy
Autor: Page E. Blas, Esther San Roman Rodriguez, Heather L. Williams, Maren K. Levin, Joshua S. K. Bell, Mariaelena Pierobon, Alexander S. Barrett, Emanuel F. Petricoin, Joyce A. O'Shaughnessy
Publikováno v: Cancer Reports, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Background Overexpression of HER2 plays an important role in cancer progression and is the target of multiple therapies in HER2‐positive breast cancer. Recent studies have also highlighted the presence of activating mutations in HER2, and
Externí odkaz: https://doaj.org/article/47960155bf034b2787b9b2901ca8c6f8
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2
Akademický článek
A multidisciplinary approach to optimizing care of patients treated with alpelisib
Autor: Hope S. Rugo, Mario E. Lacouture, Marcus D. Goncalves, Umesh Masharani, Matti S. Aapro, Joyce A. O'Shaughnessy
Publikováno v: Breast, Vol 61, Iss , Pp 156-167 (2022)
Purpose: The oral, α-specific phosphatidylinositol-3-kinase (PI3Kα) inhibitor alpelisib is the first PI3K inhibitor approved for the treatment of advanced breast cancer. As alpelisib is a relatively new therapeutic option, specific guidance and a m
Externí odkaz: https://doaj.org/article/c6c4f39f76af47a99f7d292ece4d71d7
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4
Supplementary Tables S16-S20 from A Four-gene Decision Tree Signature Classification of Triple-negative Breast Cancer: Implications for Targeted Therapeutics
Autor: Anita Grigoriadis, Andrew N.J. Tutt, Christopher J. Lord, Joyce A. O'Shaughnessy, Melinda L. Telli, Maggie C.U. Cheang, Hasan Mirza, Jelmar Quist
Supplementary Table S16: Results from the gene set enrichment analysis of 28 different immune signatures across the METABRIC-set 15 (MC subtypes) classification. Supplementary Table S17: Table representing the copy number status of the five genes par
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8811b32e022204dcee31f4820b470151
https://doi.org/10.1158/1535-7163.22504419.v1
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5
Data from Genomic Alterations Associated with Recurrence and TNBC Subtype in High-Risk Early Breast Cancers
Autor: Mark R. Lackner, Richard Bourgon, Joyce A. O'Shaughnessy, Anneleen Daemen, Heidi M. Savage, Junko Aimi, Jill M. Spoerke, Ching-Wei Chang, Akshata R. Udyavar, Timothy R. Wilson
The identification of early breast cancer patients who may benefit from adjuvant chemotherapy has evolved to include assessment of clinicopathologic features such as tumor size and nodal status, as well as several gene-expression profiles for ER-posi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39a64bbe20881e43c149267b4b8c8c49
https://doi.org/10.1158/1541-7786.c.6541339
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9
Data from A Four-gene Decision Tree Signature Classification of Triple-negative Breast Cancer: Implications for Targeted Therapeutics
Autor: Anita Grigoriadis, Andrew N.J. Tutt, Christopher J. Lord, Joyce A. O'Shaughnessy, Melinda L. Telli, Maggie C.U. Cheang, Hasan Mirza, Jelmar Quist
The molecular complexity of triple-negative breast cancers (TNBCs) provides a challenge for patient management. We set out to characterize this heterogeneous disease by combining transcriptomics and genomics data, with the aim of revealing convergent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c8d4f900299dd7ce66676144de8daa
https://doi.org/10.1158/1535-7163.c.6537732
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