Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Joyce, Bischoff"'
Publikováno v:
Journal of Vascular Anomalies, Vol 5, Iss 3, p e096 (2024)
Objective:. Infantile hemangioma (IH) is a benign vascular tumor that occurs in 5% of infants, predominantly in female and preterm neonates. Propranolol is the mainstay of treatment for IH. Given the short half-life of propranolol regarding β-adrene
Externí odkaz:
https://doaj.org/article/5b1e3ed3c1164b51b34ba1bae5ec47df
Autor:
Sana Nasim, Colette Bichsel, Stephen Dayneka, Robert Mannix, Annegret Holm, Mathew Vivero, Sanda Alexandrescu, Anna Pinto, Arin K. Greene, Donald E. Ingber, Joyce Bischoff
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Sturge-Weber syndrome (SWS), a neurocutaneous disorder, is characterized by capillary malformations (CM) in the skin, brain, and eyes. Patients may suffer from seizures, strokes, and glaucoma, and only symptomatic treatment is available. CM
Externí odkaz:
https://doaj.org/article/c5621ecbee9048b287dc17ebec595daa
Autor:
Christopher L. Sudduth, Patrick J. Smits, Matthew P. Vivero, Yu Sheng Cheng, Michal Ad, Dennis J. Konczyk, Joyce Bischoff, Matthew L. Warman, Arin K. Greene
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Somatic activating MAP2K1 mutations in endothelial cells (ECs) cause extracranial arteriovenous malformation (AVM). We previously reported the generation of a mouse line allowing inducible expression of constitutively active MAP2K1 (p.K57N)
Externí odkaz:
https://doaj.org/article/91ceb84d79d14d2ea4b48451f54c8f3a
Autor:
Montaser F Shaheen, Julie Y Tse, Ethan S Sokol, Margaret Masterson, Pranshu Bansal, Ian Rabinowitz, Christy A Tarleton, Andrey S Dobroff, Tracey L Smith, Thèrése J Bocklage, Brian K Mannakee, Ryan N Gutenkunst, Joyce Bischoff, Scott A Ness, Gregory M Riedlinger, Roman Groisberg, Renata Pasqualini, Shridar Ganesan, Wadih Arap
Publikováno v:
eLife, Vol 11 (2022)
Background: Lymphatic malformations (LMs) often pose treatment challenges due to a large size or a critical location that could lead to disfigurement, and there are no standardized treatment approaches for either refractory or unresectable cases. Met
Externí odkaz:
https://doaj.org/article/c6163aac82254054b261cfba4ae2852f
Autor:
Zahra Alvandi, Yasufumi Nagata, Livia Silva Araúujo Passos, Ali Hashemi Gheinani, J. Luis Guerrero, Jill Wylie‐Sears, Dayana Carolina Romero, Brittan A. Morris, Suzanne M. Sullivan, Koushiar M. Yaghoubian, Amirhossein Alvandi, Rosalyn M. Adam, Elena Aikawa, Robert A. Levine, Joyce Bischoff
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background The onset and mechanisms of endothelial‐to‐mesenchymal transition (EndMT) in mitral valve (MV) leaflets following myocardial infarction (MI) are unknown, yet these events are closely linked to stiffening of leaflets and development of
Externí odkaz:
https://doaj.org/article/f74bcb391dbb49d6ba7f1f73c032dd4c
Autor:
Yunzhou Dong, Yang Lee, Kui Cui, Ming He, Beibei Wang, Sudarshan Bhattacharjee, Bo Zhu, Tadayuki Yago, Kun Zhang, Lin Deng, Kunfu Ouyang, Aiyun Wen, Douglas B. Cowan, Kai Song, Lili Yu, Megan L. Brophy, Xiaolei Liu, Jill Wylie-Sears, Hao Wu, Scott Wong, Guanglin Cui, Yusuke Kawashima, Hiroyuki Matsumoto, Yoshio Kodera, Richard J. H. Wojcikiewicz, Sanjay Srivastava, Joyce Bischoff, Da-Zhi Wang, Klaus Ley, Hong Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Endothelial cell (EC) dysfunction and inflammation contribute to plaque destabilization in atherosclerosis, increasing the risk of thrombotic events. Here, the authors show that epsin promotes EC inflammation via a mechanism involving IP3R1 degradati
Externí odkaz:
https://doaj.org/article/348ebe71d77b44b0a5e82d323a1c1b08
Autor:
Caroline T. Seebauer, Matthew S. Graus, Lan Huang, Alex McCann, Jill Wylie-Sears, Frank Fontaine, Tara Karnezis, David Zurakowski, Steven J. Staffa, Frédéric Meunier, John B. Mulliken, Joyce Bischoff, Mathias Francois
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
Propranolol and atenolol, current therapies for problematic infantile hemangioma (IH), are composed of R(+) and S(–) enantiomers: the R(+) enantiomer is largely devoid of beta blocker activity. We investigated the effect of R(+) enantiomers of prop
Externí odkaz:
https://doaj.org/article/5e6caa76ca894a93a267f1f0dc061b4f
Autor:
Adrien Lupieri, Yasufumi Nagata, Livia S. A. Passos, Dakota Beker-Greene, Katherine A. Kirkwood, Jill Wylie-Sears, Zahra Alvandi, Hideyuki Higashi, Judy W. Hung, Sasha A. Singh, Joyce Bischoff, Robert A. Levine, Elena Aikawa
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Following myocardial infarction, mitral regurgitation (MR) is a common complication. Previous animal studies demonstrated the association of endothelial-to-mesenchymal transition (EndMT) with mitral valve (MV) remodeling. Nevertheless, li
Externí odkaz:
https://doaj.org/article/1cca0143f9ba4ac497b9433d0b2e35c8
Autor:
Wenquan Hu, Zhong Liu, Valerie Salato, Paula E. North, Joyce Bischoff, Suresh N. Kumar, Zhi Fang, Sujith Rajan, M. Mahmood Hussain, Qing R. Miao
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Infantile hemangioma is a vascular tumor characterized by the rapid growth of disorganized blood vessels followed by slow spontaneous involution. The underlying molecular mechanisms that regulate hemangioma proliferation and involution still are not
Externí odkaz:
https://doaj.org/article/e01edc80a8124f4bb805089613bbc913
Autor:
Lan Huang, Joyce Bischoff
Publikováno v:
Bio-Protocol, Vol 10, Iss 2 (2020)
Infantile hemangioma (IH) is a vascular tumor noted for its excessive blood vessel formation during infancy, glucose-transporter-1 (GLUT1)-positive staining of the blood vessels, and its slow spontaneous involution over several years in early childho
Externí odkaz:
https://doaj.org/article/8e269c95c6bd46d2a69bc45a4e264c11