Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joya R. Hariharan"'
Autor:
Iwona M. Wyzlic, Jianping Cai, Joya R. Hariharan, Krista Radcliffe, Dianne M. Adams, Rolf F. Barth, Albert H. Soloway
Publikováno v:
Journal of Medicinal Chemistry. 40:3887-3896
Three series of new boron-containing spermidine/spermine (SPD/SPM) analogues have been synthesized: N1- and N5-(4-carboranylbutyl) SPD/SPM derivatives (SPD-1, SPD-5, SPM-1, SPM-5); N1,N10-diethyl-N5-(4-carboranylbutyl)spermidine (DESPD-5), N1,N14-die
Publikováno v:
Polyhedron. 14:823-825
A new class of carriers for Neutron Capture Therapy, boronated polyamines, are presented that may possess a high affinity for DNA and rapid/specific uptake in brain tumors by comparison with adjacent normal brain. Two first boron-containing polyamine