Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Joya Chandra"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Targeted therapies, including small molecule inhibitors directed against aberrant kinase signaling and chromatin regulators, are emerging treatment options for high-grade gliomas (HGG). However, when translating these inhibitors into the cli
Externí odkaz:
https://doaj.org/article/0fd10c91f86f41818ccab433ecd08512
Autor:
Erin A. Hudson, Marissa Burgermaster, Sophia M. Isis, Matthew R. Jeans, Sarvenaz Vandyousefi, Matthew J. Landry, Rebecca Seguin-Fowler, Joya Chandra, Jaimie Davis
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
As rates of metabolic syndrome rise, children consume too few vegetables and too much added sugar. Because children tend to eat what is available at home, the home environment plays a key role in shaping dietary habits. This secondary analysis evalua
Externí odkaz:
https://doaj.org/article/c1c3127de1e14f4f9cf05a65bea94287
Autor:
Lea Stitzlein, Jack Adams, Matthew Luetzen, Melissa Singh, Xioaping Su, Yue Lu, Joy Gumin, Frederick Lang, Joya Chandra
Publikováno v:
Journal of Clinical and Translational Science, Vol 8, Pp 122-122 (2024)
OBJECTIVES/GOALS: LSD1 is a histone demethylase important in GBM regulation. Our goal is to design a therapeutic strategy for LSD1 inhibitors to meet clinical needs in GBM. Despite the abundance of LSD1 inhibitors, resistance emerges in GBM mouse mod
Externí odkaz:
https://doaj.org/article/32b2406f682447598b96365a07c1eba4
Autor:
Lea M. Stitzlein, Achintyan Gangadharan, Leslie M. Walsh, Deokhwa Nam, Alexsandra B. Espejo, Melissa M. Singh, Kareena H. Patel, Yue Lu, Xiaoping Su, Ravesanker Ezhilarasan, Joy Gumin, Sanjay Singh, Erik Sulman, Frederick F. Lang, Joya Chandra
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionImproved therapies for glioblastoma (GBM) are desperately needed and require preclinical evaluation in models that capture tumor heterogeneity and intrinsic resistance seen in patients. Epigenetic alterations have been well documented in
Externí odkaz:
https://doaj.org/article/8cf1141c8fd94cffbd85efb1ee005dde
Publikováno v:
Cancer Medicine, Vol 10, Iss 21, Pp 7572-7584 (2021)
Abstract Background Doxorubicin (Dox) is one of the most effective chemotherapy agents used to treat adolescent and young adult sarcoma patients. Unfortunately, Dox causes cardiotoxicities that compromise long‐term survival. We investigated whether
Externí odkaz:
https://doaj.org/article/a75fb2f1a4324304a02b3d696b502cb2
Unique Features of a Web-Based Nutrition Website for Childhood Cancer Populations: Descriptive Study
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 9, p e24515 (2021)
BackgroundChildren with cancer experience a myriad of nutritional challenges that impact their nutrition status during treatment and into survivorship. Growing evidence suggests that weight at diagnosis impacts cancer outcomes, but provider guidance
Externí odkaz:
https://doaj.org/article/712db83f18dc4d15b146c896230c138c
Publikováno v:
Computational and Systems Oncology, Vol 1, Iss 3, Pp n/a-n/a (2021)
Abstract Immunotherapy for cancer has moved from pre‐clinical hypothesis to successful clinical application in the past 15 years. However, not all cancers have shown response rates in clinical trials for these new agents. igh‐grade gliomas, in pa
Externí odkaz:
https://doaj.org/article/836e79d0476c438caea6689fc7f2d5e9
Autor:
Sankaranarayan Kannan, Mary E. Irwin, Shelley M. Herbrich, Tiewei Cheng, LaNisha L. Patterson, Marisa J. L. Aitken, Kapil Bhalla, M. James You, Marina Konopleva, Patrick A. Zweidler-McKay, Joya Chandra
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 717 (2022)
Acute myeloid leukemia (AML) is a molecularly heterogenous hematological malignancy, with one of the most common mutations being internal tandem duplication (ITD) of the juxtamembrane domain of the fms-like tyrosine kinase receptor-3 (FLT3). Despite
Externí odkaz:
https://doaj.org/article/83896798bb5e4678bb764333446a8a57
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cell therapies such as chimeric-antigen receptor (CAR) T-cells and NK cells are cutting-edge methods for treating cancer and other diseases. There is high interest in optimizing drug treatment regimens to best work together with emerging cell therapi
Externí odkaz:
https://doaj.org/article/86c9cc663e22494fb8b1cc2a206de7a2
Autor:
Margaret Raber, Joya Chandra, Mudita Upadhyaya, Vanessa Schick, Larkin L. Strong, Casey Durand, Shreela Sharma
Publikováno v:
Preventive Medicine Reports, Vol 4, Iss , Pp 23-28 (2016)
Eating out of the home has been positively associated with body weight, obesity, and poor diet quality. While cooking at home has declined steadily over the last several decades, the benefits of home cooking have gained attention in recent years and
Externí odkaz:
https://doaj.org/article/e81b375742794720b295d602e9460c9c