Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Joy Y Wu"'
Autor:
Srilatha Swami, Joshua Johnson, Lawrence A Vecchi, Matthew J Kim, Beate Lanske, Rachelle W Johnson, Joy Y Wu
Publikováno v:
JBMR Plus, Vol 6, Iss 12, Pp n/a-n/a (2022)
ABSTRACT Teriparatide, recombinant parathyroid hormone (PTH[1‐34]), and abaloparatide, an analogue of PTH related‐peptide (PTHrP[1‐34]), are both anabolic medications for osteoporosis that target the PTH receptor PTH1R. PTH1R is a G protein–c
Externí odkaz:
https://doaj.org/article/962b5a7ca153486f892fb3b1483c1987
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Using Col2.3GFP transgenic mice expressing GFP in maturing osteoblasts, we isolated Col2.3GFP+ enriched osteoblasts from 3 sources. We performed RNA-sequencing, identified 593 overlapping genes and confirmed these genes are highly enriched i
Externí odkaz:
https://doaj.org/article/ea0256b3c8264aec99af0c780bf4ca49
Publikováno v:
Biology Open, Vol 13, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/55ba1c27f9ce4ebf8ba25a555fa72618
Autor:
Srilatha Swami, Hui Zhu, Aria Nisco, Takaharu Kimura, Matthew J. Kim, Vaisakh Nair, Joy Y. Wu
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
Bone metastases are a common complication of breast cancer. We have demonstrated that intermittent administration of parathyroid hormone (PTH[1-34]) reduces the incidence of bone metastases in murine models of breast cancer by acting on osteoblasts t
Externí odkaz:
https://doaj.org/article/0bcf5ed086fd45318aa62b6ff487599c
Publikováno v:
Journal of Bone and Mineral Research. 37:1823-1842
In mammals, hematopoiesis migrates to the bone marrow during embryogenesis coincident with the appearance of mineralized bone, where hematopoietic stem cells (HSCs) and their progeny are maintained by the surrounding microenvironment or niche, and su
Publikováno v:
Journal of Bone and Mineral Research. 37:1321-1334
Osteoblasts and their progenitors play an important role in the support of hematopoiesis within the bone marrow (BM) microenvironment. We have previously reported that parathyroid hormone receptor (PTH1R) signaling in osteoprogenitors is required for
Autor:
Andrea Eisen, Mark R. Somerfield, Melissa K. Accordino, Phillip S. Blanchette, Mark J. Clemons, Sukhbinder Dhesy-Thind, Melissa S. Dillmon, Stella D'Oronzo, Glenn G. Fletcher, Elizabeth S. Frank, Sigrun Hallmeyer, Issam Makhoul, Beverly Moy, Alia Thawer, Joy Y. Wu, Catherine H. Van Poznak
Publikováno v:
Journal of Clinical Oncology. 40:787-800
PURPOSE To update recommendations of the American Society of Clinical Oncology (ASCO)-Ontario Health (Cancer Care Ontario [CCO]) adjuvant bone-modifying agents in breast cancer guideline. METHODS An Expert Panel conducted a systematic review to ident
Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline
Autor:
Ghada El-Hajj Fuleihan, Gregory A Clines, Mimi I Hu, Claudio Marcocci, M Hassan Murad, Thomas Piggott, Catherine Van Poznak, Joy Y Wu, Matthew T Drake
Publikováno v:
The Journal of clinical endocrinology and metabolism.
Background Hypercalcemia of malignancy (HCM) is the most common metabolic complication of malignancies, but its incidence may be declining due to potent chemotherapeutic agents. The high mortality associated with HCM has declined markedly due to the
Publikováno v:
Biomaterials. 299:122163
Autor:
Pamela B. Davis, Emma A. Meagher, Claire Pomeroy, William L. Lowe, Arthur H. Rubenstein, Joy Y. Wu, Anne B. Curtis, Rebecca D. Jackson
Publikováno v:
Nature Medicine. 28:436-438