Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Joy Rathjen"'
Autor:
Alexandra J Harvey, Carmel O'Brien, Jack Lambshead, John R Sheedy, Joy Rathjen, Andrew L Laslett, David K Gardner
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193949 (2018)
Reprogramming somatic cells to a pluripotent cell state (induced Pluripotent Stem (iPS) cells) requires reprogramming of metabolism to support cell proliferation and pluripotency, most notably changes in carbohydrate turnover that reflect a shift fro
Externí odkaz:
https://doaj.org/article/72ebe40befa2460da0c6aef954027d1a
Autor:
Boon Siang Nicholas Tan, Joly Kwek, Chong Kum Edwin Wong, Nicholas J Saner, Charlotte Yap, Fernando Felquer, Michael B Morris, David K Gardner, Peter D Rathjen, Joy Rathjen
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163244 (2016)
Multiple pluripotent cell populations, which together comprise the pluripotent cell lineage, have been identified. The mechanisms that control the progression between these populations are still poorly understood. The formation of early primitive ect
Externí odkaz:
https://doaj.org/article/bdda700d644b4543996b3a3770dcdcaa
Publikováno v:
Stem Cells International, Vol 2016 (2016)
The differentiation of pluripotent stem cells is associated with extensive changes in metabolism, as well as widespread remodeling of the epigenetic landscape. Epigenetic regulation is essential for the modulation of differentiation, being responsibl
Externí odkaz:
https://doaj.org/article/e7baa5fec9184a56958d0e1f3082a763
Autor:
Joy Rathjen, Peter D. Rathjen
Publikováno v:
The Scientific World Journal, Vol 2, Pp 690-700 (2002)
Recent interest in the generation of neural lineages by differentiation of embryonic stem cells arises from the opportunities represented by a developmentally normal, unlimited source of material that can be manipulated genetically with precision. Se
Externí odkaz:
https://doaj.org/article/d0f62bd54dfa49f8ac81c577f7534958
Autor:
Svetlana Vassilieva, Hwee Ngee Goh, Kevin X Lau, James N Hughes, Mary Familari, Peter D Rathjen, Joy Rathjen
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38645 (2012)
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation. This complexity of endoderm cell populations is mirrored during pluripotent cell d
Externí odkaz:
https://doaj.org/article/5f29d826423b4e4caaa8e01bfb193c31
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12555 (2010)
BackgroundEmbryonic stem (ES) cells hold considerable promise as a source of cells with therapeutic potential, including cells that can be used for drug screening and in cell replacement therapies. Differentiation of ES cells into the somatic lineage
Externí odkaz:
https://doaj.org/article/33e9ae7416684234b5e9b7b226f0b774
Autor:
Aaron J. Robinson, Guoying Zhao, Joy Rathjen, Peter D. Rathjen, Rhonda G. Hutchinson, Helen J. Eyre, Kim M. Hemsley, John J. Hopwood
Publikováno v:
Cell Transplantation, Vol 19 (2010)
Pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, have generated much excitement about their prospects for use in cell transplantation therapies. This is largely attributable to their virtually unlimited
Externí odkaz:
https://doaj.org/article/2a4dab968f6f486b8c28c0d561a899a8
Autor:
James N Hughes, Jennifer M Washington, Zhiqiang Zheng, Xiuwen K Lau, Charlotte Yap, Peter D Rathjen, Joy Rathjen
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5579 (2009)
In the mammal, the pluripotent cells of embryo differentiate and commit to either the mesoderm/endoderm lineages or the ectoderm lineage during gastrulation. In culture, the ability to direct lineage choice from pluripotent cells into the mesoderm/en
Externí odkaz:
https://doaj.org/article/65e472fa99d34763ae9cdab1271caf78
Publikováno v:
Mechanisms of Development. 141:32-39
The developmental outcomes of preimplantation mammalian embryos are regulated directly by the surrounding microenvironment, and inappropriate concentrations of amino acids, or the loss of amino acid-sensing mechanisms, can be detrimental and impact f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd76bb14a163e8d667907511d388260
https://doi.org/10.1016/j.mod.2016.06.003
https://doi.org/10.1016/j.mod.2016.06.003
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2016 (2016)
Stem Cells International, Vol 2016 (2016)
The differentiation of pluripotent stem cells is associated with extensive changes in metabolism, as well as widespread remodeling of the epigenetic landscape. Epigenetic regulation is essential for the modulation of differentiation, being responsibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982f8eb3b8e2b28192a510b4d9d55ff1
https://doi.org/10.1155/2016/1816525
https://doi.org/10.1155/2016/1816525