Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Joy O. Olayiwola"'
Autor:
Sonia G. Rao, Crystal A. Tonnessen-Murray, Benjamin T. Vinson, Ashkan Shahbandi, Joy O. Olayiwola, Nathan Ungerleider, James G. Jackson, Douglas B. Chrisey, Christopher J. Lord, Lucas B. Murray, Wesley D. Frey
Publikováno v:
Journal of Cell Biology. 218:3827-3844
In chemotherapy-treated breast cancer, wild-type p53 preferentially induces senescence over apoptosis, resulting in a persisting cell population constituting residual disease that drives relapse and poor patient survival via the senescence-associated
Autor:
Nathan Ungerleider, Ashlyn Y. Anderson, Ashkan Shahbandi, Joy O. Olayiwola, Sonia G. Rao, Wesley D. Frey, James G. Jackson
Publikováno v:
Cell Death Differ
TP53 wild-type breast tumors rarely undergo a complete pathological response after chemotherapy treatment. These patients have an extremely poor survival rate and studies show these tumors preferentially undergo senescence instead of apoptosis. These