Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joy M. Polefrone"'
Autor:
Nicholas E. Sherman, Joy M. Polefrone, Kristina Nelson, J. Thomas Parsons, Donald F. Hunt, Jeffrey Shabanowitz, Erin D. Jeffery, Alan F. Horwitz, Mark W. Mayhew, Stephen J. Pratt, Jay W. Fox
Publikováno v:
Journal of Cell Science. 120:3911-3918
βPIX (PAK1-interacting exchange factor beta, encoded by ARHGEF7 ) and PAK1 (p21 activated kinase) are interacting proteins that form a signaling module that mediates a number of cellular activities pertinent to cell migration ([Kim et al., 2001][1];
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43674adec75aa6d61d93e554e5fbd3c
https://doi.org/10.1242/jcs.008177
https://doi.org/10.1242/jcs.008177
Autor:
Sylvie D. Freeman, Charles Craddock, Hugo De La Peña, Guy Pratt, Mark Cobbold, Michael E. Williams, Jennifer Cottine, Victor H. Engelhard, Oliver Goodyear, Joy M. Polefrone, Jeffrey Shabanowitz, Jennifer G. Abelin, Andrew Norris, Angela L. Zarling, Hsing-Wen Huang, Stacy A. Malaker, James E. Turner, Jie Qian, Donald F. Hunt, Kara L. Cummings, Ann M. English, Sarah A Penny
Publikováno v:
Cobbold, M, De La Pena, H, Norris, A, Polefrone, J M, Qian, J, English, A M, Cummings, K L, Penny, S, Turner, J E, Cottine, J, Abelin, J G, Malaker, S A, Zarling, A L, Huang, H-W, Goodyear, O, Freeman, S D, Shabanowitz, J, Pratt, G, Craddock, C, Williams, M E, Hunt, D F & Engelhard, V H 2013, ' MHC class I–associated phosphopeptides are the targets of memory-like immunity in Leukemia ', Science Translational Medicine, vol. 5, no. 203, 203ra125 . https://doi.org/10.1126/scitranslmed.3006061
Deregulation of signaling pathways is a hallmark of malignant transformation. Signaling-associated phosphoproteins can be degraded to generate cancer-specific phosphopeptides that are presented by major histocompatibility complex (MHC) class I and II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f768142573feac7488518be7bbdd16f
https://purehost.bath.ac.uk/ws/files/133105285/Cobbold_2013_Sci_Trans_Med.pdf
https://purehost.bath.ac.uk/ws/files/133105285/Cobbold_2013_Sci_Trans_Med.pdf
Autor:
Joy M. Polefrone, Marina Ostankovitch, Michelle L. Altrich-VanLith, Victor H. Engelhard, Claudio A. Mosse, Donald F. Hunt, Jeffrey Shabanowitz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(8)
Although multiple components of the class I MHC processing pathway have been elucidated, the participation of nonproteasomal cytosolic enzymes has been largely unexplored. In this study, we provide evidence for multiple cytosolic mechanisms in the ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fe2e630dd07af88662903e4aee868e
https://pubmed.ncbi.nlm.nih.gov/17015730
https://pubmed.ncbi.nlm.nih.gov/17015730
Autor:
Angela L. Zarling, Victor H. Engelhard, Anne M. Evans, Joy M. Polefrone, Leann M. Mikesh, Donald F. Hunt, Jeffrey Shabanowitz, Sarah T. Lewis
Alterations in phosphorylation of cellular proteins are a hallmark of malignant transformation. Degradation of these phosphoproteins could generate cancer-specific class I MHC-associated phosphopeptides recognizable by CD8 + T lymphocytes. In a compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c1f3766fa5714c003e757dd725a2b9
https://europepmc.org/articles/PMC1595446/
https://europepmc.org/articles/PMC1595446/
Autor:
Victor H. Engelhard, Andrea M. De Santis, Michael E. Williams, Jie Qian, Fiyaz Mohammed, Donald F. Hunt, Benjamin E. Willcox, Joy M. Polefrone, Andrew Norris, Angela L. Zarling, Mark Cobbold, J. Shabanowitz
Publikováno v:
Blood. 110:285-285
CD8+ T cells have been identified as potent effectors of the adaptive anti-tumor immune response. So far, only a small number of tumor antigens have been objectively linked to the oncogenic processes. Alteration in phosphorylation status of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2681a91973d792f84014667fa49eb01f
https://doi.org/10.1182/blood.v110.11.285.285
https://doi.org/10.1182/blood.v110.11.285.285
Autor:
L.M. Hopkins, J. Shabanowitz, Joy M. Polefrone, Angela L. Zarling, Victor H. Engelhard, Anne M. Evans, Donald F. Hunt
Publikováno v:
Human Immunology. 66:117
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efca6747e68027c7e4b36d6416ab3e6
https://doi.org/10.1016/j.humimm.2005.08.224
https://doi.org/10.1016/j.humimm.2005.08.224
Autor:
Cobbold, Mark, De La Peña, Hugo, Norris, Andrew, Polefrone, Joy M., Qian, Jie, English, Ann Michelle, Cummings, Kara L., Penny, Sarah, Turner, James E., Cottine, Jennifer, Abelin, Jennifer G., Malaker, Stacy A., Zarling, Angela L., Hsing-Wen Huang, Goodyear, Oliver, Freeman, Sylvie D., Shabanowitz, Jeffrey, Pratt, Guy, Craddock, Charles, Williams, Michael E.
Publikováno v:
Science Translational Medicine; 9/18/2013, Vol. 5 Issue 203, p1-10, 10p