Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Joy M. Folkvord"'
Autor:
Matthew T. Ollerton, Joy M. Folkvord, Kristina K. Peachman, Soumya Shashikumar, Elaine B. Morrison, Linda L. Jagodzinski, Sheila A. Peel, Mohammad Khreiss, Richard T. D’Aquila, Sofia Casares, Mangala Rao, Elizabeth Connick
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A major barrier in the use of humanized mice as models of HIV-1 (HIV) infection is the inadequate generation of virus-specific antibody responses. Humanized DRAGA (hDRAGA) mice generate antigen-specific class switched antibodies to several pathogens,
Externí odkaz:
https://doaj.org/article/410118cf98d94607b05e18da9d5c9118
Autor:
Matthew T. Ollerton, Joy M. Folkvord, Andriana La Mantia, David A. Parry, Amie L. Meditz, Martin D. McCarter, Richard T. D’Aquila, Elizabeth Connick
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Follicular helper CD4+ T cells (TFH) are highly permissive to HIV and major foci of virus expression in both untreated and treated infection. Follicular regulatory CD4+ T cells (TFR) limit TFH numbers and function in vitro and in vivo. We evaluated t
Externí odkaz:
https://doaj.org/article/3737dd4c5dd84da584fd3965bf4df15c
Autor:
Gabriela M. Webb, Shengbin Li, Gwantwa Mwakalundwa, Joy M. Folkvord, Justin M. Greene, Jason S. Reed, Jeffery J. Stanton, Alfred W. Legasse, Theodore Hobbs, Lauren D. Martin, Byung S. Park, James B. Whitney, Emily K. Jeng, Hing C. Wong, Douglas F. Nixon, R. Brad Jones, Elizabeth Connick, Pamela J. Skinner, Jonah B. Sacha
Publikováno v:
Blood Advances, Vol 2, Iss 2, Pp 76-84 (2018)
Abstract: Sequestering of latent HIV in follicular helper T cells within B-cell follicles that largely exclude cytotoxic T cells is a major barrier to cellular immune-based approaches to eradicate HIV. Here, we show that the clinical-grade human inte
Externí odkaz:
https://doaj.org/article/eefee46bd3354844aa52e77eb0fb72eb
Autor:
Brodie Miles, Shannon M Miller, Joy M Folkvord, David N Levy, Eva G Rakasz, Pamela J Skinner, Elizabeth Connick
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005924 (2016)
During chronic HIV infection, viral replication is concentrated in secondary lymphoid follicles. Cytotoxic CD8 T cells control HIV replication in extrafollicular regions, but not in the follicle. Here, we show CXCR5hiCD44hiCD8 T cells are a regulator
Externí odkaz:
https://doaj.org/article/8147e7299b2641d8b287e7c1a8dd8b66
Autor:
Benjamin Trinité, Chi N Chan, Caroline S Lee, Saurabh Mahajan, Yang Luo, Mark A Muesing, Joy M Folkvord, Michael Pham, Elizabeth Connick, David N Levy
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110719 (2014)
HIV-1 hijacks and disrupts many processes in the cells it infects in order to suppress antiviral immunity and to facilitate its replication. Resting CD4 T cells are important early targets of HIV-1 infection in which HIV-1 must overcome intrinsic bar
Externí odkaz:
https://doaj.org/article/512728fc6e724f9e8b132fac1e8e0316
Autor:
Gwantwa Mwakalundwa, Justin M. Greene, Alfred W. Legasse, Douglas F. Nixon, Emily K. Jeng, Hing C. Wong, Jason S. Reed, Joy M. Folkvord, Lauren D. Martin, Jonah B. Sacha, Gabriela M. Webb, Byung Park, Jeffery J. Stanton, Pamela J. Skinner, R. Brad Jones, Elizabeth Connick, Shengbin Li, Theodore R. Hobbs, James B. Whitney
Publikováno v:
Blood Advances. 2:76-84
National Institutes of Health (NIH) from the National Institute of Allergy and Infectious Diseases (NIAID) [R21 All 28970-01A1]; National Institutes of Health (NIH) from the NIH Office, and Martin Delaney BELIEVE collaborator NIAID award [P51 OD01109
Autor:
Lara Vojnov, Mauricio A Martins, Jorge R Almeida, Zachary Ende, Eva G Rakasz, Matthew R Reynolds, Enrique J Leon, Kim L Weisgrau, Benjamin J Burwitz, Joy M Folkvord, Marlon G Veloso de Santana, Patrícia C Costa Neves, Elizabeth Connick, Pamela J Skinner, Emma Gostick, David H O'Connor, Nancy A Wilson, Myrna C Bonaldo, Ricardo Galler, David A Price, Danny C Douek, David I Watkins
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23515 (2011)
Several lines of evidence suggest that HIV/SIV-specific CD8(+) T cells play a critical role in the control of viral replication. Recently we observed high levels of viremia in Indian rhesus macaques vaccinated with a segment of SIVmac239 Gag (Gag(45-
Externí odkaz:
https://doaj.org/article/7194b0666af841749b79ab89ca7b9445
Autor:
Nina C. Flerin, Elizabeth Connick, Rebecca M. Lynch, Maria Korom, Jian Hua Zheng, Ronald Truong, R. Brad Jones, Harris Goldstein, Talia M. Mota, Joy M. Folkvord, Ariola Bardhi, Erika Benko, Colin Kovacs
Publikováno v:
Journal of Virology. 93
Curing HIV infection has been thwarted by the persistent reservoir of latently infected CD4+ T cells, which reinitiate systemic infection after antiretroviral therapy (ART) interruption. To evaluate reservoir depletion strategies, we developed a nove
Autor:
Pamela J. Skinner, Eva G. Rakasz, Elizabeth Connick, Gwantwa Mwakalundwa, Reece K. Wagstaff, Joy M. Folkvord, Katalin J. Kovács, Shengbin Li, Aaron Rendahl
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007311 (2019)
PLoS Pathogens
PLoS Pathogens
CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV producing cells concentrate during chronic infection. It is not known, however, if antigen
Autor:
Shengbin Li, Gwantwa Mwakalundwa, Joy M. Folkvord, Eva G. Rakasz, Katalin J. Kovács, Pamela J. Skinner, Reece K. Wagstaff, Aaron Rendahl, Elizabeth Connick
CD8+ T cells play an important role in controlling of HIV and SIV infections. However, these cells are largely excluded from B cell follicles where HIV and SIV producing cells concentrate during chronic infection. It is not known, however, if antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8f7cff567f34b8dfd50840ec3df925
https://doi.org/10.1101/407528
https://doi.org/10.1101/407528