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pro vyhledávání: '"Joy Lipka-Diamond"'
Autor:
Joy Lipka-Diamond, Vance G. Fowler, Pamela S. Douglas, Raymond Schuch, G. Ralph Corey, Gregory J. Moran, Marcus J. Zervos, Luis Jauregui-Peredo, Cara Cassino, Mark E. Rupp, Robert A Wise, Adam Bressler, David C. Evans, Roger J. Pomerantz, Anita Das
Publikováno v:
J Clin Invest
BACKGROUND: Novel therapeutic approaches are critically needed for Staphylococcus aureus bloodstream infections (BSIs), particularly for methicillin-resistant S. aureus (MRSA). Exebacase, a first-in-class antistaphylococcal lysin, is a direct lytic a
Publikováno v:
Open Forum Infectious Diseases
Background Exebacase, a lysin (cell wall hydrolase), is the first direct lytic agent to report Phase 2 study results in Staphylococcus aureus bacteremia including endocarditis. Among MRSA patients enrolled in this randomized, double-blind, placebo, c