Dissimilar gene repertoires of Dickeya solani involved in the colonization of lesions and roots of Solanum tuberosum

Autor: Kévin Robic, Euphrasie Munier, Géraldine Effantin, Joy Lachat, Delphine Naquin, Erwan Gueguen, Denis Faure

Publikováno v: Frontiers in Plant Science, Vol 14 (2023)

Dickeya and Pectobacterium species are necrotrophic pathogens that macerate stems (blackleg disease) and tubers (soft rot disease) of Solanum tuberosum. They proliferate by exploiting plant cell remains. They also colonize roots, even if no symptoms

Externí odkaz: https://doaj.org/article/c72beed01e7c4071bb993ca8f86fc27a

Comparative analysis of mutational robustness of the intrinsically disordered viral protein VPg and of its interactor eIF4E.

Autor: Jocelyne Walter, Justine Charon, Yihua Hu, Joy Lachat, Thomas Leger, Guillaume Lafforgue, Amandine Barra, Thierry Michon

Publikováno v: PLoS ONE, Vol 14, Iss 2, p e0211725 (2019)

Conformational intrinsic disorder is a feature present in many virus proteins. Intrinsically disordered regions (IDRs) have weaker structural requirement than ordered regions and mutations in IDRs could have a lower impact on the virus fitness. This

Externí odkaz: https://doaj.org/article/08fd821f86ad4bd6a47c83017408f78a

The antibiotic phazolicin displays a dual mode of uptake in Gram-negative bacteria

Autor: Dmitrii Y. Travin, Armelle Vigouroux, Satomi Inaba-Inoue, Feng Qu, Romain Jouan, Joy Lachat, Dmitry Sutormin, Svetlana Dubiley, Konstantinos Beis, Solange Moréra, Konstantin Severinov, Peter Mergaert

Phazolicin (PHZ) is a peptide antibiotic exhibiting narrow-spectrum activity against rhizobia closely related to its producer Rhizobium sp. Pop5. Using genetic and biochemical techniques, we here identified BacA and YejABEF as two importers of PHZ in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfce6e8f984174bbca2815100912cd8
https://hal.science/hal-03833311

Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage

Autor: Delphine Thibaut, Joy Lachat, Rémi Le Borgne, Allon Weiner, Jean-Marc Verbavatz, Alice Pascault

Publikováno v: Nature Communications
Nature Communications, 2022, 13 (1), pp.3781. ⟨10.1038/s41467-022-31237-z⟩

SummaryThe opportunistic fungal pathogen Candida albicans is normally commensal, residing in the mucosa of most healthy individuals. In susceptible hosts, its filamentous hyphal form can invade epithelial layers leading to superficial or severe syste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce135123eaa99a9e9bce1bf06627766
https://doi.org/10.1101/2021.09.09.459426

The biotroph Agrobacterium tumefaciens thrives in tumors by exploiting a wide spectrum of plant host metabolites

Autor: Peter Mergaert, Florian Lamouche, Delphine Naquin, Léo Mathias, Denis Faure, Almudena Gonzalez-Mula, Joy Lachat

Publikováno v: New Phytologist
New Phytologist, Wiley, 2019, 222 (1), pp.455--467. ⟨10.1111/nph.15598⟩
The New Phytologist
The New Phytologist, 2018, 222 (1), pp.455--467. ⟨10.1111/nph.15598⟩
New Phytologist, 2019, 222 (1), pp.455--467. ⟨10.1111/nph.15598⟩

International audience; Agrobacterium tumefaciens is a niche-constructing biotroph that exploits host plant metabolites. We combined metabolomics, transposon-sequencing (Tn-seq), transcriptomics and reverse genetics to characterize A. tumefaciens pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1fa8e011b3b54e33eebee3842ed145
https://hal.archives-ouvertes.fr/hal-02178888/document