Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Joy J. Chen"'
Autor:
Giorgia Cioccoloni, Alex Websdale, Liqian Ma, Erik R. Nelson, Madeline A. Henn, Priscilia Lianto, Joy J. Chen, Baek Kim, Laura M. Wastall, J. Bernadette Moore, James L. Thorne, Arindam Pramanik, Samantha A Hutchinson, Chrysa Soteriou, Hanne Roberg-Larsen, Ailsa Rose, Bethany Jill Williams, Thomas A. Hughes
Publikováno v:
Oncogene
Triple negative breast cancer (TNBC) is challenging to treat successfully because targeted therapies do not exist. Instead, systemic therapy is typically restricted to cytotoxic chemotherapy, which fails more often in patients with elevated circulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3c067f82a853ef98be6b1868b6deaa
http://hdl.handle.net/10852/92654
http://hdl.handle.net/10852/92654
Autor:
Laura M. Wastall, Priscilia Lianto, Thomas A. Hughes, Madeline A. Henn, Erik R. Nelson, Alex Websdale, Samantha A Hutchinson, Giorgia Cioccoloni, Chrysa Soteriou, Joy J. Chen, Hanne Roberg-Larsen, Liqian Ma, Bethany Jill Williams, Ailsa Rose, Baek Kim, James L. Thorne, J. Bernadette Moore
Triple negative breast cancer (TNBC) is challenging to treat successfully because targeted therapies do not exist. Instead, systemic therapy is typically restricted to cytotoxic chemotherapy, which fails more often in patients with elevated circulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfde5a31acbb2190c142e4e5787d643a
https://doi.org/10.1101/2020.08.04.235697
https://doi.org/10.1101/2020.08.04.235697
Autor:
Madeline A. Henn, Liqian Ma, Sunghee Park, Amy E. Baek, Karan Menon, David J. Shapiro, Som G. Nanjappa, Sisi He, Sayyed Hamed Shahoei, Lawrence Wang, Adam T Nelson, Erik R. Nelson, Joy J. Chen, Chaeyeon Han, Anna Vardanyan
Publikováno v:
Cancer Lett
Breast cancer remains one of the leading causes of cancer mortality in the US. Elevated cholesterol is a major risk factor for breast cancer onset and recurrence, while cholesterol-lowering drugs, such as statins, are associated with a good prognosis
Autor:
Sayyed Hamed Shahoei, Madeline A. Henn, Erik R. Nelson, Varsha Vembar, Liqian Ma, Adam T Nelson, Ashley E Mathews, Yu Wang, Anna Vardanyan, Joy J. Chen, Lionel Apetoh
Publikováno v:
Journal of the Endocrine Society
Immune checkpoint blockade has had underwhelming responses in breast cancer, in part due to the highly immune suppressive microenvironment. As a result, breast cancer continues to be the second most common cancer-related mortality amongst women, prov
Autor:
Liqian Ma, Anna Vardanyan, Sisi He, Varsha Vembar, Amy E. Baek, Adam T Nelson, Joy J. Chen, Erik R. Nelson, Joanna E. Burdette
Publikováno v:
Endocr Relat Cancer
There is an urgent need for more effective strategies to treat ovarian cancer. Elevated cholesterol levels are associated with a decreased progression-free survival time (PFS) while statins are protective. 27-Hydroxycholesterol (27HC), a primary meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0294b77d52cdfe2f1fab558ac7d00e43
https://europepmc.org/articles/PMC6824983/
https://europepmc.org/articles/PMC6824983/
Autor:
David J. Shapiro, Joy J. Chen, Sunghee Park, Som G. Nanjappa, Adam T Nelson, Amy E. Baek, Erik R. Nelson, Liqian Ma, Karan Menon, Sisi He, Madeline A. Henn, Lawrence Wang, Anna Vardanyan, Chaeyeon Han, Sayyed Hamed Shahoei
Publikováno v:
Cancer Immunology Research. 9:PR006-PR006
Breast cancer remains one of the leading causes of cancer mortality in the US. Elevated cholesterol is a major risk factor for breast cancer onset and recurrence, while cholesterol-lowering drugs, such as statins, are associated with a good prognosis
Autor:
Adam T Nelson, Varsha Vembar, Liqian Ma, Lionel Apetoh, Madeline A. Henn, Erik R. Nelson, Ashley E Mathews, Joy J. Chen, Sayyed Hamed Shahoei
Publikováno v:
Cancer Immunology Research. 8:A93-A93
Breast cancer continues to be the second most common cancer-related mortality among women, providing strong rationale for the development of new therapeutic approaches. Cholesterol and its metabolism have been implicated in the progression of breast
Autor:
Erik R. Nelson, Lionel Apetoh, Ashley E Mathews, Madeline A. Henn, Adam T Nelson, Varsha Vembar, Sayyed Hamed Shahoei, Liqian Ma, Joy J. Chen
Publikováno v:
Cancer Research. 80:P6-05
It has become clear that cholesterol metabolism and homeostasis play significant roles in the progression of breast cancer. Specifically, elevated circulating cholesterol is a poor prognostic, while patients taking cholesterol-lowering drugs such as
Publikováno v:
Cancer Research. 79:1893-1893
Breast cancer continues to be the most commonly diagnosed cancer among women, with the majority of mortality being associated with the metastatic spread of this disease. In terms of onset, genetic drivers such as mutations in BCR1/2 account for only
Autor:
Cuong D. Tran, Alice Yam, Toni Kline, Gang Yin, Maureen Fitch Bruhns, Venita I. De Almeida, James Zawada, Stellanie Krimm, Mary Rose Masikat, Willy Solis, Ryan Stafford, Joy J. Chen, Sihong Zhou, Jeffrey A. Hanson, Cristina Abrahams, Trevor J. Hallam, Mark Lupher, Tyler H. Heibeck, Ganapathy Sarma, Xiaofan Li, Robert Henningsen, Adam Galan, Alexander Steiner, Krishna Bajjuri, Heather Stephenson
Publikováno v:
Cancer Research. 78:1782-1782
Folate receptor alpha (FolRα) is a glycosylphosphatidylinositol linked cell-surface glycoprotein that is widely expressed in serous and epithelial ovarian cancer, endometrial adenocarcinoma, non-small cell lung cancer and triple negative breast canc