Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Joy Guedia"'
Autor:
Nina E. Weisser, Mario Sanches, Eric Escobar-Cabrera, Jason O’Toole, Elizabeth Whalen, Peter W. Y. Chan, Grant Wickman, Libin Abraham, Kate Choi, Bryant Harbourne, Antonios Samiotakis, Andrea Hernández Rojas, Gesa Volkers, Jodi Wong, Claire E. Atkinson, Jason Baardsnes, Liam J. Worrall, Duncan Browman, Emma E. Smith, Priya Baichoo, Chi Wing Cheng, Joy Guedia, Sohyeong Kang, Abhishek Mukhopadhyay, Lisa Newhook, Anders Ohrn, Prajwal Raghunatha, Matteo Zago-Schmitt, Joseph D. Schrag, Joel Smith, Patricia Zwierzchowski, Joshua M. Scurll, Vincent Fung, Sonia Black, Natalie C. J. Strynadka, Michael R. Gold, Leonard G. Presta, Gordon Ng, Surjit Dixit
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
The success of HER2-targeted cancer therapy is limited by treatment resistance. Here, the authors engineer an anti-HER2 biparatopic antibody with multiple mechanisms of action including induction of HER2 clustering to trigger complement dependent cyt
Externí odkaz:
https://doaj.org/article/8a871ad93e594eeba832492229b1329b
Autor:
Graham Garnett, Katina Mak, Renee Duan, Truman Hirkala-Schaefer, Manuel Lasalle, Nichole Escalante, Joy Guedia, Kara Moyes, Sam Lawn, Raffaele Colombo, Jamie Rich, Stuart Barnscher
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4132834160757918e939da119230db75
https://doi.org/10.1136/jitc-2022-sitc2022.1185
https://doi.org/10.1136/jitc-2022-sitc2022.1185
Autor:
Michael G. Brant, Graham A.E. Garnett, Joy Guedia, Manuel Lasalle, Samuel Lawn, Mark E. Petersen, Renee Duan, Jose Mendez-Campos, Truman Hirkala-Schaefer, Geoffrey C. Winters, Stuart D. Barnscher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. :129348
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68eaaf8136ba0037d3802506c42a7a50
https://doi.org/10.1016/j.bmcl.2023.129348
https://doi.org/10.1016/j.bmcl.2023.129348
Autor:
Bryant T. Harbourne, Jason O'Toole, Chi Wing Cheng, Gerry Rowse, Peter Wing Yiu Chan, Neil Josephson, Browman Duncan, Nina E. Weisser, Grant Raymond Wickman, Libin Abraham, Michael R. Gold, Joy Guedia, Surjit Bhimarao Dixit
Publikováno v:
Cancer Research. 81:1005-1005
HER2-directed therapies have improved clinical outcomes for many patients with HER2-positive breast and gastric cancer. Despite these successes, there remains a need to develop improved HER2-targeted therapies for these and other HER2-expressing tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4525958fca51a8cfb4208f92477748
https://doi.org/10.1158/1538-7445.am2021-1005
https://doi.org/10.1158/1538-7445.am2021-1005
Autor:
Minho Kang, William L. Dewey, Paola Brun, Sukhada Bhave, Hamid I. Akbarali, Sylvia Fitting, Kurt F. Hauser, Joy Guedia
Publikováno v:
Scientific Reports
The loss of gut epithelium integrity leads to translocation of microbes and microbial products resulting in immune activation and drives systemic inflammation in acquired immunodeficiency syndrome (AIDS) patients. Although viral loads in HIV patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7cd4adf626e0aa38b653df9a1723ed