Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Joy G. Mohanty"'
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/fbfc82881ee24c34a4d82187dd7dfad8
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The primary role for erythrocytes is oxygen transport that requires the reversible binding of oxygen to hemoglobin. There are, however, secondary reactions whereby the erythrocyte can generate reactive oxygen species (ROS) and nitric oxide (NO). ROS
Externí odkaz:
https://doaj.org/article/966736cc5b4e4286bdf9cfa6bb575269
Autor:
Luke B. Ravi, Suresh Poosala, Dongchoon Ahn, Francis J. Chrest, Edward L. Spangler, Rajadas Jayakumar, Enika Nagababu, Joy G. Mohanty, Mark Talan, Donald K. Ingram, Joseph M. Rifkind
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 28-37 (2005)
Vascular amyloidosis in Alzheimer's disease (AD) results in the exposure of red blood cells to β-amyloid fibrils (Aβ). The potential in vivo ramifications of this exposure have been investigated by injecting Aβ1–40 alone or Aβ-bound mouse red b
Externí odkaz:
https://doaj.org/article/306fa1039dd0455dbd0e1cb2d0f9cdde
Autor:
Xiuli Dan, Joy G. Mohanty, Vilhelm A. Bohr, Mansi Babbar, Deborah L. Croteau, Jingyan Tian, Anthony Moore, Noah Wechter
Publikováno v:
Nucleic Acids Res
Mitochondria are vital for cellular energy supply and intracellular signaling after stress. Here, we aimed to investigate how mitochondria respond to acute DNA damage with respect to mitophagy, which is an important mitochondrial quality control proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64be721beb6f3578bd5c90206f17a31
https://doi.org/10.1093/nar/gkaa393
https://doi.org/10.1093/nar/gkaa393
Autor:
Julie A. Mattison, Luigi Ferrucci, Joy G. Mohanty, Ruin Moaddel, Jacqueline Lovett, Tyler G Demarest, Mark P. Mattson, Vilhelm A. Bohr, Gia Thinh D. Truong
Publikováno v:
Analytical Biochemistry. 572:1-8
The reduction-oxidation state of NAD+/NADH is critical for cellular health with NAD+ and its metabolites playing critical roles in aging and pathologies. Given the inherent autooxidation of reduced dinucleotides (i.e. NADH/NADPH), and the well-establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f9bc1c8de830cfd2ce5a047e09bfb16
https://doi.org/10.1016/j.ab.2019.02.019
https://doi.org/10.1016/j.ab.2019.02.019
Publikováno v:
Ageing Res Rev
Alterations in olfactory functions are proposed to be early biomarkers for neurodegeneration. Many neurodegenerative diseases are age-related, including two of the most common, Parkinson’s disease (PD) and Alzheimer’s disease (AD). The establishm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7296d5fd87d4660e4abc1737d9f068e6
https://doi.org/10.1016/j.arr.2021.101416
https://doi.org/10.1016/j.arr.2021.101416
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2f7ba3c5cd0e806eed3828f0edbdd6
https://doi.org/10.3389/fphys.2019.00492
https://doi.org/10.3389/fphys.2019.00492
Autor:
Tyler G, Demarest, Gia Thinh D, Truong, Jacqueline, Lovett, Joy G, Mohanty, Julie A, Mattison, Mark P, Mattson, Luigi, Ferrucci, Vilhelm A, Bohr, Ruin, Moaddel
Publikováno v:
Anal Biochem
The reduction-oxidation state of NAD(+)/NADH is critical for cellular health with NAD(+) and its metabolites playing critical roles in aging and pathologies. Given the inherent autooxidation of reduced dinucleotides (i.e. NADH/NADPH), and the well-es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a96fbdf14f25607c0874d712262e09a4
https://pubmed.ncbi.nlm.nih.gov/30822397
https://pubmed.ncbi.nlm.nih.gov/30822397
Autor:
Mustafa Nazir Okur, Tyler G Demarest, Vilhelm A. Bohr, Louise S. Christiansen, Joy G. Mohanty, Yujun Hou, Nima Borhan Fakouri, Deborah L. Croteau
Publikováno v:
The FEBS journal. 286(6)
The biology of aging is an area of intense research, and many questions remain about how and why cell and organismal functions decline over time. In mammalian cells, genomic instability and mitochondrial dysfunction are thought to be among the primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0691e34c5671b7ccaaf727b9fdbfb19
https://pubmed.ncbi.nlm.nih.gov/30238623
https://pubmed.ncbi.nlm.nih.gov/30238623
Publikováno v:
Biochemistry. 54:6712-6723
The reduction of nitrite by deoxyhemoglobin to nitric oxide (NO) has been proposed as a mechanism for the transfer of NO bioactivity from the red blood cell (RBC) to the vasculature. This transfer can increase vascular dilatation. The major challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daeaf07c2552840bc7dc75fc029ea164
https://doi.org/10.1021/acs.biochem.5b00643
https://doi.org/10.1021/acs.biochem.5b00643