Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joy E. Kirkpatrick"'
Publikováno v:
Epigenetics, Vol 13, Iss 5, Pp 557-572 (2018)
Periodontal disease (PD) afflicts 46% of Americans with no effective adjunctive therapies available. While most pharmacotherapy for PD targets bacteria, the host immune response is responsible for driving tissue damage and bone loss in severe disease
Externí odkaz:
https://doaj.org/article/2388ac6f1f1c49bda1a8ba473b9271de
Autor:
Jessica D Hathaway‐Schrader, Nicole A Poulides, Matthew D Carson, Joy E Kirkpatrick, Amy J Warner, Brooks A Swanson, Eliza V Taylor, Michael E Chew, Sakamuri V Reddy, Bei Liu, Caroline Westwater, Chad M Novince
Publikováno v:
JBMR Plus, Vol 4, Iss 3, Pp n/a-n/a (2020)
ABSTRACT The commensal gut microbiota critically regulates immunomodulatory processes that influence normal skeletal growth and maturation. However, the influence of specific microbes on commensal gut microbiota osteoimmunoregulatory actions is unkno
Externí odkaz:
https://doaj.org/article/239f928106c2427b9b3d7460aab1b8ae
Autor:
Caroline Westwater, Matthew D Carson, J. Ignacio Aguirre, Amy J Warner, Joy E Kirkpatrick, Chad M. Novince, Alexander V. Alekseyenko, Alexa Corker, Brooks A Swanson, Jessica D. Hathaway-Schrader
Publikováno v:
FASEB J
Periodontitis-mediated alveolar bone loss is caused by dysbiotic shifts in the commensal oral microbiota that upregulate proinflammatory osteoimmune responses. Study purpose was to determine whether antimicrobial-induced disruption of the commensal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a49fb99b35128d5ef0070bd23cd50f
https://doi.org/10.1096/fj.202101169r
https://doi.org/10.1096/fj.202101169r
Autor:
Huan Huan Chen, Yuri K. Peterson, Matthew Dunworth, Patrick M. Woster, Joy E Kirkpatrick, Steven L. Holshouser, Tracy Murray-Stewart, Pieter B. Burger, Robert A. Casero
Publikováno v:
MedChemComm. 10:778-790
We have previously described the synthesis and evaluation of 3,5-diamino-1,2,4-triazole analogues as inhibitors of the flavin-dependent histone demethylase LSD1. These compounds are potent inhibitors of LSD1 without activity against monoamine oxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5077ca1f99d63743d7d6ca98438baca
https://doi.org/10.1039/c8md00610e
https://doi.org/10.1039/c8md00610e
Autor:
Robert A. Casero, Patrick M. Woster, Mayra C. Robinson, Joy E Kirkpatrick, Rebecca Cafiero, Hyacinth I. Hyacinth, Steven L. Holshouser
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 24, Pp 14750-14758 (2020)
ACS Omega, Vol 5, Iss 24, Pp 14750-14758 (2020)
Sickle cell disease (SCD) is caused by a single nucleotide polymorphism on chromosome 11 in the β-globin gene. The resulting mutant hemoglobin S (HbS) is a poor oxygen transporter and causes a variety of vascular symptoms and organ failures. At birt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a173e9fa2fe4f9b2cf6041781be3558
https://pubmed.ncbi.nlm.nih.gov/32596612
https://pubmed.ncbi.nlm.nih.gov/32596612
Autor:
Amy J Warner, Joy E Kirkpatrick, Eliza V Taylor, Jessica D. Hathaway-Schrader, Bei Liu, Brooks A Swanson, Michael E. Chew, Sakamuri V. Reddy, Matthew D Carson, Caroline Westwater, Nicole A. Poulides, Chad M. Novince
Publikováno v:
JBMR Plus, Vol 4, Iss 3, Pp n/a-n/a (2020)
JBMR Plus
JBMR Plus
The commensal gut microbiota critically regulates immunomodulatory processes that influence normal skeletal growth and maturation. However, the influence of specific microbes on commensal gut microbiota osteoimmunoregulatory actions is unknown. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2490a03a99b29f653323e0994b0e21db
https://doi.org/10.1002/jbm4.10338
https://doi.org/10.1002/jbm4.10338
Autor:
Michael B. Chavez, Michael E. Chew, Alexander V. Alekseyenko, José Aguirre, Jessica D. Hathaway-Schrader, Nicole A. Poulides, Chad M. Novince, Emily Huang, Joy E Kirkpatrick, Heidi M. Steinkamp
Publikováno v:
The American journal of pathology. 189(2)
Commensal gut microbiota-host immune responses are experimentally delineated via gnotobiotic animal models or alternatively by antibiotic perturbation of gut microbiota. Osteoimmunology investigations in germ-free mice, revealing that gut microbiota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266a8f0af4529b89c67124f83e9bfe90
https://pubmed.ncbi.nlm.nih.gov/30665557
https://pubmed.ncbi.nlm.nih.gov/30665557
Autor:
Michael B. Chavez, Joy E Kirkpatrick, Michael S. Valerio, Bethany A. Herbert, D. S. Basilakos, Jessica D. Hathaway-Schrader, Keith L. Kirkwood
Publikováno v:
Journal of periodontal research. 52(3)
Background and Objective Periodontal disease pathogenesis is comprised of the complex inflammatory immune response to oral bacterial dysbiosis. Like other inflammatory diseases, there is sexual dimorphism evident in periodontal diseases. During perio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b8d8a4cb08d6791760fb95f3b8b9e3
https://pubmed.ncbi.nlm.nih.gov/27509894
https://pubmed.ncbi.nlm.nih.gov/27509894