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Abstract P1-02-05: A genome-wide functional genomics screen reveals unique co-driver mutations of mutant TP53 promoting cellular heterogeneity during breast cancer progression

Autor: Dustin Grief, Anasuya Pal, Laura Gonzalez-Malerva, Seron Eaton, Chenxi Xu, Grant Christensen, Joy Blain, Nicholas Mellor, Jason Steel, Chitrak Gupta, Ellen Streitwieser, Abhishek Singharoy, Jin Park, Joshua LaBaer

Publikováno v: Cancer Research. 82:P1-02

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks three major drug-targetable receptors, ER, PR, and HER2. TNBC patients have much worse 5-year survival rates (60%) in contrast to 90% for other breast cancer su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4fa0023d2e1e5aa1475cf61e90a5fa0
https://doi.org/10.1158/1538-7445.sabcs21-p1-02-05

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