Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Joy A. Pai"'
Autor:
Joy A. Pai, Ansuman T. Satpathy
Publikováno v:
Nat Methods
T cells express T cell receptors (TCRs) composed of somatically recombined TCRα and TCRβ chains, which mediate recognition of major histocompatibility complex (MHC)-antigen complexes and drive the antigen-specific adaptive immune response to pathog
Autor:
Joy A. Pai, Matthew D. Hellmann, Jennifer L. Sauter, Marissa Mattar, Hira Rizvi, Hyung Jun Woo, Nisargbhai Shah, Evelyn M. Nguyen, Fathema Z. Uddin, Alvaro Quintanal-Villalonga, Joseph M. Chan, Parvathy Manoj, Viola Allaj, Marina K. Baine, Umesh K. Bhanot, Mala Jain, Irina Linkov, Fanli Meng, David Brown, Jamie E. Chaft, Andrew J. Plodkowski, Mathieu Gigoux, Helen H. Won, Triparna Sen, Daniel K. Wells, Mark T.A. Donoghue, Elisa de Stanchina, Jedd D. Wolchok, Brian Loomis, Taha Merghoub, Charles M. Rudin, Andrew Chow, Ansuman T. Satpathy
Publikováno v:
Cancer Cell. 41:776-790.e7
Autor:
Charles M. Rudin, Daniel K. Wells, Taha Merghoub, P. Manoj, Triparna Sen, H. J. Woo, Marissa Mattar, Jennifer L. Sauter, Joy A. Pai, Hira Rizvi, Mark T.A. Donoghue, Viola Allaj, Matthew D. Hellmann, Ansuman T. Satpathy, Jamie E. Chaft, Nisargbhai S. Shah, Helen Won, Andrew J. Plodkowski, Marina K. Baine, E. De Stanchina, Fathema Uddin, Brian Houck-Loomis, Álvaro Quintanal-Villalonga, Jedd D. Wolchok, Andrew Chow, Joseph M. Chan
Paired T cell receptor and RNA single cell sequencing (scTCR/RNA-seq) has allowed for enhanced resolution of clonal T cell dynamics in cancer. Here, we report a scTCR/RNA-seq dataset of 162,062 single T cells from 31 tissue regions, including tumor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::972611c6bab01a045c5dec2909ec877c
https://doi.org/10.1101/2021.09.27.461389
https://doi.org/10.1101/2021.09.27.461389
Autor:
Kenneth M. Murphy, Tenzin Yangdon, Joy A. Pai, Saravanan Raju, Katalin Sandor, Sunnie Hsiung, Ansuman T. Satpathy, Renee Wu, Yu Xia, Yanyan Qi, Takeshi Egawa, Bence Daniel, Robert D. Schreiber, Mariko Okamoto
SummaryShortly after priming, the fate of activated CD4 T cells is segregated into BCL6+ follicular helper T (Tfh) and BCL6− effector (Teff) cells. However, it remains unknown how these subsets are sustained in the presence of chronic antigen stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c16d94e6a9a73abb9cf697c6852bd8
https://doi.org/10.1101/2021.08.06.455141
https://doi.org/10.1101/2021.08.06.455141
Autor:
Yu, Xia, Katalin, Sandor, Joy A, Pai, Bence, Daniel, Saravanan, Raju, Renee, Wu, Sunnie, Hsiung, Yanyan, Qi, Tenzin, Yangdon, Mariko, Okamoto, Chun, Chou, Kamir J, Hiam-Galvez, Robert D, Schreiber, Kenneth M, Murphy, Ansuman T, Satpathy, Takeshi, Egawa
Publikováno v:
Immunity. 55(7)
Soon after activation, CD4
Autor:
Yu Xia, Katalin Sandor, Joy A. Pai, Bence Daniel, Saravanan Raju, Renee Wu, Sunnie Hsiung, Yanyan Qi, Tenzin Yangdon, Mariko Okamoto, Chun Chou, Kamir J. Hiam-Galvez, Robert D. Schreiber, Kenneth M. Murphy, Ansuman T. Satpathy, Takeshi Egawa
Publikováno v:
Immunity. 55:1200-1215.e6
Autor:
Mila Jankovic, Victor A. Ramos, Marina Caskey, Julio C. C. Lorenzi, Joy A. Pai, Thiago Y. Oliveira, Pilar Mendoza, Michel C. Nussenzweig, Ching-Lan Lu, Christian Gaebler, Lilian Nogueira
Publikováno v:
The Journal of Experimental Medicine
HIV-1 cure research seeks to decrease or eliminate the latent reservoir. The evaluation of such curative strategies requires accurate measures of the reservoir. Gaebler et al. describe a combined multicolor qPCR and next-generation sequencing method
Autor:
Harald Hartweger, Joy A. Pai, Michel C. Nussenzweig, Gray, Andrew T. McGuire, Marie Pancera, Justin J. Taylor, Pia Dosenovic, Connor Weidle, Ervin E. Kara, Junli Feng, K.R. Parks, Leonidas Stamatatos, K. Bhullar, Abigail Wall, Eddy S. Thientosapol, Anna-Klara Pettersson
Publikováno v:
The Journal of Experimental Medicine
We developed an anti-idiotypic antibody that specifically engages target B cells while mitigating off-target responses. This approach can be used as a vaccine strategy for variable pathogens where specific precursor B cells have been identified to co
Autor:
Yu Xia, Katalin Sandor, Joy A. Pai, Bence Daniel, Saravanan Raju, Renee Wu, Sunnie Hsiung, Yanyan Qi, Tenzin Yangdon, Mariko Okamoto, Robert D Schreiber, Kenneth M Murphy, Ansuman Satpathy, Takeshi Egawa
Publikováno v:
The Journal of Immunology. 208:169.08-169.08
Shortly after priming, the fate of activated CD4 T cells is segregated into BCL6+ follicular helper T (Tfh) and BCL6− effector (Teff) cells. However, it remains unknown how these subsets are sustained in the presence of chronic antigen stimulation.
Autor:
Nico Pfeifer, Marina Caskey, Allison L. Butler, Theodora K. Karagounis, Clara Lehmann, Kanika Jain, Lilian Nogueira, Henning Gruell, Christoph Wyen, Gerd Fätkenheuer, Stefan Scholten, Maggi Witmer-Pack, Kerstin Fiddike, Joy A. Pai, Nicole L. Yates, Kelly E. Seaton, Jörg Janne Vehreschild, Till Schoofs, Juan Dizon, Roy M. Gulick, Isabelle Suárez, Thiago Y. Oliveira, Georgia D. Tomaras, Katrina G. Millard, Florian Klein, Michel C. Nussenzweig, Yotam Bar-On, Irina Shimeliovich, Michael S. Seaman, Jill Horowitz, Yehuda Z. Cohen, Lisa Handl, Shiraz A. Belblidia
Publikováno v:
Nature medicine
Nature Medicine
Nat Med
Nature Medicine
Nat Med
Monotherapy of HIV-1 infection with single antiretroviral agents is ineffective because error-prone HIV-1 replication leads to the production of drug-resistant viral variants1,2. Combinations of drugs can establish long-term control, however, antiret