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Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Glycoprotein G of vesicular stomatitis virus (VSV) enables viral entry by binding to the major VSV receptor LDL-R. Here the authors present crystal structures of G in complex with two distinct CR domains of LDL-R, identifying structural determinants
Externí odkaz:
https://doaj.org/article/c655891b73d54aeb8adf1a017f3f60af
Autor:
Jovan Nikolic, Romain Le Bars, Zoé Lama, Nathalie Scrima, Cécile Lagaudrière-Gesbert, Yves Gaudin, Danielle Blondel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Negative strand RNA viruses, such as rabies virus, induce formation of cytoplasmic inclusions for genome replication. Here, Nikolic et al. show that these so-called Negri bodies (NBs) have characteristics of liquid organelles and they identify the mi
Externí odkaz:
https://doaj.org/article/9a955e81f9324d589e3ef61679b3fd39
Autor:
Nadia Jeremiah, Hermine Ferran, Konstantina Antoniadou, Kevin De Azevedo, Jovan Nikolic, Mathieu Maurin, Philippe Benaroch, Nicolas Manel
Publikováno v:
Journal of Experimental Medicine. 220
In innate immune cells, intracellular sensors such as cGAS-STING stimulate type I/III interferon (IFN) expression, which promotes antiviral defense and immune activation. However, how IFN-I/III expression is controlled in adaptive cells is poorly und
Publikováno v:
IEEE Transactions on Network and Service Management. 18:2728-2741
Large-scale decentralized systems of autonomous agents interacting via asynchronous communication often experience the following self-healing dilemma: fault detection inherits network uncertainties making a remote faulty process indistinguishable fro
Autor:
Jovan Nikolic, Joseph Ackerman, Sarah Taheraly, Thierry Rose, Ouardia Aït-Mohamed, Martine Ben Amar, Jean-François Joanny, Philippe Benaroch
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005942 (2016)
Stress granules (SGs) are membrane-less dynamic structures consisting of mRNA and protein aggregates that form rapidly in response to a wide range of environmental cellular stresses and viral infections. They act as storage sites for translationally
Externí odkaz:
https://doaj.org/article/0653c14be34744c58da445c5f81c0010
Publikováno v:
Cancer immunology research. 10(10)
Anticancer immunotherapies are therapeutics aimed at eliciting immune responses against tumor cells. Immunotherapies based on adoptive transfer of engineered immune cells have raised great hopes of cures because of the success of chimeric antigen rec
Autor:
Barbara Maier, Ana Sastre-Perona, Pauline Hamon, Philippe Benaroch, Esperanza Agulló-Pascual, Andrew Leader, Brian D. Brown, Markus Brown, Ephraim Kenigsberg, Christie Chang, Blanca M. Morales, Markus Schober, Jessica LeBerichel, Matthew D. Park, Thomas U. Marron, Alexandra Tabachnikova, Jovan Nikolic, Christine Moussion, Leanna Troncoso, Julio A. Aguirre-Ghiso, Maxime Dhainaut, Miriam Merad, Erica Dalla, Boris Reizis, Steven T. Chen, Maria Casanova-Acebes, Catherine M. Sawai
Publikováno v:
Nature
Nature, Nature Publishing Group, 2021, 595 (7868), pp.578-584. ⟨10.1038/s41586-021-03651-8⟩
Nature, Nature Publishing Group, 2021, 595 (7868), pp.578-584. ⟨10.1038/s41586-021-03651-8⟩
Macrophages have a key role in shaping the tumour microenvironment (TME), tumour immunity and response to immunotherapy, which makes them an important target for cancer treatment1,2. However, modulating macrophages has proved extremely difficult, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1859ddc8577c12368e12807498ad1b5e
https://hal.archives-ouvertes.fr/hal-03380716
https://hal.archives-ouvertes.fr/hal-03380716
Publikováno v:
médecine/sciences. 34:203-205