Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jovan Mirkovitch"'
Publikováno v:
Journal of Virological Methods. 99:9-21
A procedure is described that allows the simple identification and sorting of live human cells that transcribe actively the HIV virus, based on the detection of GFP fluorescence in cells. Using adenoviral vectors for gene transfer, an expression cass
Publikováno v:
Gene. 255:169-184
Chromatin architecture plays a decisive role in many aspects of transcription regulation. We have tested the role of specific chromatin structures in c- fos gene regulation, using a gene transfer system based on episomes derived from the Epstein–Ba
Publikováno v:
Gene. 255:185-194
Transcription elongation regulates c-fos expression in mouse and human cells. In the inactive state of the gene, RNA polymerases are engaged only in the promoter-proximal region. Upon activation, RNA polymerases move efficiently along the complete ge
Autor:
Anne-Christine Souici, Larry K. Keefer, Pierrette Hausel, Jovan Mirkovitch, Emanuela Felley-Bosco
Publikováno v:
Carcinogenesis. 21:281-287
Exposing the human bronchial epithelial cell line BEAS-2B to the nitric oxide (NO) donor sodium 1-(N,N-diethylamino)diazen-1-ium-1, 2-diolate (DEA/NO) at an initial concentration of 0.6 mM while generating superoxide ion at the rate of 1 microM/min w
Autor:
Jovan Mirkovitch, Stéphane Pinaud
Publikováno v:
Journal of Molecular Biology. 280:785-798
The molecular mechanisms underlying transcription elongation and their role in gene regulation are poorly characterized in eukaryotes. A number of genes, however, have been proposed to be regulated at the level of transcription elongation, including
Publikováno v:
Gene. 211:141-150
Hepatocyte growth factor/scatter factor (HGF/SF) is a recently characterised molecule with many remarkable functions. Its involvement in important processes such as cell proliferation, cell migration, morphogenesis and organ development implies that
Autor:
Larry K. Keefer, Andrea M. A. Pfeifer, Stefan Ambs, Katherine Macé, Emanuela Felley-Bosco, Jovan Mirkovitch, Curtis C. Harris
Publikováno v:
Carcinogenesis. 16:2069-2074
Nitric oxide (NO) is a cellular messenger which is mutagenic in bacteria and human TK6 cells and induces deamination of 5-methylcytosine (5meC) residues in vitro. The aims of this study were : (i) to investigate whether NO induces 5meC deamination in
Publikováno v:
European Journal of Biochemistry. 216:353-360
The expression of genes in the liver is mostly controlled at the transcriptional level and depends on the regulatory interactions between cis-acting sequences and trans-acting molecules. Proximal promoters and distant enhancers in combination with a
Autor:
Jovan Mirkovitch
Publikováno v:
Immunobiology. 198(1-3)
Regulation of transcription is a key feature of the HIV-1 life cycle. In recent years, various sequence elements and transcription factors have been shown to participate in HIV-1 transcription control. New evidence, however, has shown that chromatin