Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication.

Autor: Hasegawa Y; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kim J; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Korea Brain Research Institute, Daegu, Republic of Korea., Ursini G; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD, USA., Jouroukhin Y; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences SUNY, University at Buffalo, Buffalo, NY, USA., Zhu X; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Miyahara Y; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Xiong F; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Madireddy S; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Obayashi M; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lutz B; Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.; Leibniz Institute for Resilience Research (LIR) gGmbH, Mainz, Germany., Sawa A; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Brown SP; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA., Pletnikov MV; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences SUNY, University at Buffalo, Buffalo, NY, USA. mvpletni@buffalo.edu., Kamiya A; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. akamiya1@jhmi.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Oct 25; Vol. 14 (1), pp. 6559. Date of Electronic Publication: 2023 Oct 25.

Loss of Astrocytic µ Opioid Receptors Exacerbates Aversion Associated with Morphine Withdrawal in Mice: Role of Mitochondrial Respiration.

Autor: Murlanova K; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Jouroukhin Y; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Novototskaya-Vlasova K; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Huseynov S; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Pletnikova O; Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Morales MJ; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Guan Y; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurological Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Kamiya A; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Bergles DE; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Dietz DM; Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA., Pletnikov MV; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Publikováno v: Cells [Cells] 2023 May 17; Vol. 12 (10). Date of Electronic Publication: 2023 May 17.

Homeostatic regulation of neuronal excitability by probiotics in male germ-free mice.

Autor: Kim J; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kim DW; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lee A; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mason M; Department of Biology, University of New Mexico, Albuquerque, NM, USA., Jouroukhin Y; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Woo H; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea., Yolken RH; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Stanley Division of Developmental Neurovirology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pletnikov MV; Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Physiology and Biophysics, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.

Publikováno v: Journal of neuroscience research [J Neurosci Res] 2022 Feb; Vol. 100 (2), pp. 444-460. Date of Electronic Publication: 2021 Dec 21.

Oligodendrocytes, the Forgotten Target of Gene Therapy.

Autor: Ozgür-Gunes, Yasemin¹ (AUTHOR) yasemin.ozgurgunes@umassmed.edu, Le Stunff, Catherine^2,3,4 (AUTHOR) catherine.le-stunff@inserm.fr, Bougnères, Pierre^2,3,5 (AUTHOR) pierre@therapydesignconsulting.com

Publikováno v: Cells (2073-4409). Dec2024, Vol. 13 Issue 23, p1973. 35p.

MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration.

Autor: Philips T; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Mironova YA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Jouroukhin Y; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Chew J; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Vidensky S; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Farah MH; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Pletnikov MV; Department of Physiology and Biophysics, Jacobs School of Medicine and Biomedical Sciences SUNY, University at Buffalo, Buffalo, NY 14203, USA., Bergles DE; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD 21205, USA., Morrison BM; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: bmorris7@jhmi.edu., Rothstein JD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Electronic address: jrothstein@jhmi.edu.

Publikováno v: Cell reports [Cell Rep] 2021 Jan 12; Vol. 34 (2), pp. 108610.