Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

Autor: Kime, L, Vincent, HA, Gendoo, DMA, Jourdan, SS, Fishwick, CWG, Callaghan, AJ, McDowall, KJ

Publikováno v: Scientific Reports

The Escherichia coli endoribonuclease RNase E is central to the processing and degradation of all types of RNA and as such is a pleotropic regulator of gene expression. It is essential for growth and was one of the first examples of an endonuclease t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b87c5e395d310f9104ef71fb81f642e
https://doi.org/10.1038/srep09781

The first small-molecule inhibitors of members of the ribonuclease E family.

Autor: Kime L; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK., Vincent HA; School of Biological Sciences and Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth, PO1 2DY, UK., Gendoo DM; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK., Jourdan SS; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK., Fishwick CW; 1] Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK [2] School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK., Callaghan AJ; School of Biological Sciences and Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth, PO1 2DY, UK., McDowall KJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK.

Publikováno v: Scientific reports [Sci Rep] 2015 Jan 26; Vol. 5, pp. 8028. Date of Electronic Publication: 2015 Jan 26.

Biophysical characterisation of the nucleocapsid protein from a highly pathogenic porcine reproductive and respiratory syndrome virus strain.

Autor: Jourdan SS; Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 6JP, UK., Osorio FA, Hiscox JA

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2012 Mar 09; Vol. 419 (2), pp. 137-41. Date of Electronic Publication: 2012 Jan 28.

The sequence of sites recognised by a member of the RNase E/G family can control the maximal rate of cleavage, while a 5'-monophosphorylated end appears to function cooperatively in mediating RNA binding.

Autor: Jourdan SS; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Kime L, McDowall KJ

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2010 Jan 01; Vol. 391 (1), pp. 879-83. Date of Electronic Publication: 2009 Nov 27.

Sensing of 5' monophosphate by Escherichia coli RNase G can significantly enhance association with RNA and stimulate the decay of functional mRNA transcripts in vivo.

Autor: Jourdan SS; Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, England, UK., McDowall KJ

Publikováno v: Molecular microbiology [Mol Microbiol] 2008 Jan; Vol. 67 (1), pp. 102-15.