Hydroxychloroquine in the treatment of adult patients with Covid-19 infection in a primary care setting (LIBERTY): A structured summary of a study protocol for a randomised controlled trial

Autor: Petri J. Vainio, Pauliina Hietasalo, Anna-Liisa Koivisto, Susanna Kääriäinen, Jari Turunen, Mika Virtala, Jouni Vuorinen, Mika Scheinin

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-3 (2021)

Abstract Objectives The primary objective of this study is to evaluate the therapeutic potential of hydroxychloroquine (HCQ) in the treatment of adult patients with PCR-confirmed Covid-19 infection in a primary open-care setting, as compared to place

Externí odkaz: https://doaj.org/article/0cd899f104824b0797e9da1a987be223

Hydroxychloroquine in the treatment of adult patients with Covid-19 infection in a primary care setting (LIBERTY): A structured summary of a study protocol for a randomised controlled trial

Autor: Jari Turunen, Anna-Liisa Koivisto, Mika Virtala, Petri J. Vainio, Pauliina Hietasalo, Jouni Vuorinen, Susanna Kääriäinen, Mika Scheinin

Publikováno v: Trials
Trials, Vol 22, Iss 1, Pp 1-3 (2021)

Objectives The primary objective of this study is to evaluate the therapeutic potential of hydroxychloroquine (HCQ) in the treatment of adult patients with PCR-confirmed Covid-19 infection in a primary open-care setting, as compared to placebo. The s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17bdf9c9a68bfada3c8bae6353b4cac
http://europepmc.org/articles/PMC7797713

Fixed-Dose Combination of Tafluprost and Timolol in the Treatment of Open-Angle Glaucoma and Ocular Hypertension: Comparison with Other Fixed-Combination Products

Autor: Jouni Vuorinen, Teppo Huttunen, Juhani Tuominen, Norbert Pfeiffer, Gábor Holló, Auli Ropo

Publikováno v: Advances in Therapy

A new preservative-free fixed-dose combination of 0.0015% tafluprost, a prostaglandin F2α analog, and 0.5% timolol (TAF/TIM; Santen Oy, Tampere, Finland), a beta-adrenergic antagonist has recently been developed. The intraocular pressure (IOP) reduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a68358b6d511c11e4843f4e7d3fcf17
https://doi.org/10.1007/s12325-014-0151-7

Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo

Autor: Miia Turpeinen, Mika Scheinin, Terhi Lehtinen, Pasi Tapanainen, Camilla Stjernschantz, Jouni Vuorinen, Marita Kailajärvi, Risto Lammintausta, Olavi Pelkonen, Jouko Uusitalo

Publikováno v: International Journal of Molecular Sciences
Volume 14
Issue 7
Pages 14064-14075
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 14064-14075 (2013)

The objective of these investigations was to determine the possible effects of the novel selective estrogen receptor modulator, ospemifene, on cytochrome P450 (CYP)-mediated drug metabolism. Ospemifene underwent testing for possible effects on CYP en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61adb9239508801f6d030457f1a53aa6
https://doi.org/10.3390/ijms140714064

A Simple Three-Step Procedure for Parametric and Nonparametric Assessment of Bioequivalence

Autor: Jari Turunen, Jouni Vuorinen

Publikováno v: Drug Information Journal. 31:167-180

A simple three-step approach for the assessment of bioequivalence is proposed. According to the decision rule of this approach, average bioequivalence is assessed first (Step 1). If approved, then ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::50c5a25992e0058fb554c9eadc3029e8
https://doi.org/10.1177/009286159703100124