Zobrazeno 1 - 10
of 461
pro vyhledávání: '"Jouni, Hirvonen"'
Autor:
Sen Li, Han Gao, Haoji Wang, Xiaolin Zhao, Da Pan, Idaira Pacheco-Fernández, Ming Ma, Jianjun Liu, Jouni Hirvonen, Zehua Liu, Hélder A. Santos
Publikováno v:
Bioactive Materials, Vol 43, Iss , Pp 376-391 (2025)
Metal-organic frameworks (MOFs) hold promise as theranostic carriers for atherosclerosis. However, to further advance their therapeutic effects with higher complexity and functionality, integrating multiple components with complex synthesis procedure
Externí odkaz:
https://doaj.org/article/77aa524103d943718756e2b8ae1de2ef
Autor:
João P. Martins, Patrícia Figueiredo, Shiqi Wang, Erika Espo, Elena Celi, Beatriz Martins, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Mauri A. Kostiainen, Christian Celia, Vincenzo Cerullo, Tapani Viitala, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos
Publikováno v:
Bioactive Materials, Vol 9, Iss , Pp 299-315 (2022)
Oral insulin delivery could change the life of millions of diabetic patients as an effective, safe, easy-to-use, and affordable alternative to insulin injections, known by an inherently thwarted patient compliance. Here, we designed a multistage nano
Externí odkaz:
https://doaj.org/article/889f6173d53143808abea3aeaaf3d585
Autor:
Wei Li, Jian Chen, Shujie Zhao, Tianhe Huang, Huiyan Ying, Claudia Trujillo, Giuseppina Molinaro, Zheng Zhou, Tao Jiang, Wei Liu, Linwei Li, Yuancheng Bai, Peng Quan, Yaping Ding, Jouni Hirvonen, Guoyong Yin, Hélder A. Santos, Jin Fan, Dongfei Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
High drug loading improves therapeutic efficacy and reduces side effects in drug delivery. Here, the authors use controlled diffusion of solvents to precipitate drug nanoparticles in polymer particles while the polymer is solidifying and demonstrate
Externí odkaz:
https://doaj.org/article/e39845004e78498eb75d36f39e99809a
Autor:
Voitto Känkänen, Micaela Fernandes, Zehua Liu, Jani Seitsonen, Sami-Pekka Hirvonen, Janne Ruokolainen, João F. Pinto, Jouni Hirvonen, Vimalkumar Balasubramanian, Hélder A. Santos
Publikováno v:
Journal of Colloid and Interface Science, 633, 383-395. ACADEMIC PRESS INC ELSEVIER SCIENCE
Funding Information: V. Känkänen and H.A. Santos acknowledge Bayer Oy (Finland) for financial support. H.A. Santos acknowledges also the Sigrid Jusélius Foundation and the UMCG Research Fund for financial support. Publisher Copyright: © 2022 The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc5e2433a93ba94601595f48735accd
https://doi.org/10.1016/j.jcis.2022.11.124
https://doi.org/10.1016/j.jcis.2022.11.124
Autor:
Han Gao, Shiqi Wang, Qiang Long, Ruoyu Cheng, Wenhua Lian, Artturi Koivuniemi, Ming Ma, Baoding Zhang, Jouni Hirvonen, Xianming Deng, Zehua Liu, Xiaofeng Ye, Hélder A. Santos
Publikováno v:
Journal of Controlled Release, 357, 120-132. Elsevier Bedrijfsinformatie b.v.
Rational design and fabrication of small interfering RNA (siRNA) delivery system with simple production scheme, specific targeting capability, responsiveness to endogenous stimuli and potential multi-functionalities remains technically challenging. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042f92e923f27dbf5eaba9298dd70223
https://research.rug.nl/en/publications/049d4932-53de-4203-b320-c1af6745f980
https://research.rug.nl/en/publications/049d4932-53de-4203-b320-c1af6745f980
Autor:
Yunzhan Li, Zehua Liu, Li Li, Wenhua Lian, Yaohui He, Elbadry Khalil, Ermei Mäkilä, Wenzhong Zhang, Giulia Torrieri, Xueyan Liu, Jingyi Su, Yuanming Xiu, Flavia Fontana, Jarno Salonen, Jouni Hirvonen, Wen Liu, Hongbo Zhang, Hélder A. Santos, Xianming Deng
Publikováno v:
Advanced Science, Vol 7, Iss 15, Pp n/a-n/a (2020)
Abstract The analysis of nanoparticles’ biocompatibility and immunogenicity is mostly performed under a healthy condition. However, more clinically relevant evaluation conducted under pathological condition is less known. Here, the immunogenicity a
Externí odkaz:
https://doaj.org/article/9d0d0b500307412a8174dd248012223a
Autor:
Mohammad-Ali Shahbazi, Mahsa Sedighi, Tomás Bauleth-Ramos, Krishna Kant, Alexandra Correia, Narges Poursina, Bruno Sarmento, Jouni Hirvonen, Hélder A. Santos
Publikováno v:
ACS Omega, Vol 3, Iss 12, Pp 18444-18455 (2018)
Externí odkaz:
https://doaj.org/article/75098f03623a44f398485898cdfa8724
Autor:
Dongfei Liu, Yuancheng Bai, Zifan Zhang, Hélder A. Santos, Jie Zhang, Wei Li, Jouni Hirvonen, Bowen Wan, Xuri Wu, Feng Zhang, Tianhe Huang, Zehua Liu, Peng Quan, Pei Zhang, Jin Fan, Alexandra Correia, Cong Li, Ting Cai
Publikováno v:
Nano Letters. 21:9458-9467
Engineering a system with a high mass fraction of active ingredients, especially water-soluble proteins, is still an ongoing challenge. In this work, we developed a versatile surface camouflage strategy that can engineer systems with an ultrahigh mas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1813158c824b91d6ec0eb54dca128b18
https://doi.org/10.1021/acs.nanolett.1c02438
https://doi.org/10.1021/acs.nanolett.1c02438
Autor:
Giulia Torrieri, Imran Iqbal, Flavia Fontana, Virpi Talman, Heidi Liljenbäck, Andriana Putri, Wail Nammas, Johan Rajander, Xiang Guo‐Li, Philip S. Low, Tambet Teesalu, Anne Roivainen, Jouni Hirvonen, Heikki Ruskoaho, Vimalkumar Balasubramanian, Antti Saraste, Hélder A. Santos
Publikováno v:
Advanced Functional Materials, n/a(n/a):2303658. WILEY-V C H VERLAG GMBH
Myocardial infarction (MI) is the leading cause of death worldwide. However, current therapies are unable to restore the function of the injured myocardium. Advanced approaches, such as stimulation of cardiomyocyte (CM) proliferation are promising, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32e3443e8114445edd58970574332a9
Wiley Online Library
Wiley Online Library
Autor:
Sandra López Cerdá, Flavia Fontana, Shiqi Wang, Alexandra Correia, Giuseppina Molinaro, Rubén Pareja Tello, Jouni Hirvonen, Christian Celia, Goncalo Barreto, Hélder A. Santos
Publikováno v:
Advanced Therapeutics. Wiley
Macrophages play a key role in the development of many diseases, like tissue injury, cancer and autoimmune diseases. So far, single-drug loaded nanoparticles have been developed to target macrophages. Nevertheless, macrophage dysregulation can induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9327520ad0054069b6e8b8ab1f33a168
https://research.rug.nl/en/publications/c94fdee6-24dd-4653-93ba-6026a63c0353
https://research.rug.nl/en/publications/c94fdee6-24dd-4653-93ba-6026a63c0353
