Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jouko A. Lukkarinen"'
Autor:
Lance DelaBarre, Jouko A. Lukkarinen, Olli Gröhn, Michael Garwood, Joseph Lin, Risto A. Kauppinen, Heidi I. Mäkelä
Publikováno v:
Magnetic Resonance in Medicine. 49:172-176
The ability of on-resonance T(1rho) (T(1rho)) and off-resonance T(1rho) (T(1rho)(off)) measurements to indicate acute cerebral ischemia in a rat model of transient middle cerebral artery (MCA) occlusion was investigated at 4.7 T. T(1rho) was determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52af945eddf6721ced54a5c6826b6282
https://doi.org/10.1002/mrm.10356
https://doi.org/10.1002/mrm.10356
Publikováno v:
Journal of Pharmacy and Pharmacology. 54:1565-1569
Activation of the γ-amino butyric acid (GABA)-ergic system might protect against the damage that occurs after cerebral ischaemia. We examined this hypothesis by administering diazepam to rats subjected to transient middle cerebral artery occlusion (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9163922c480b2a9dc35d14df6e373559
https://doi.org/10.1211/002235702180
https://doi.org/10.1211/002235702180
Autor:
Olli Gröhn, Risto A. Kauppinen, Jari Koistinaho, Jouko A. Lukkarinen, Eija Koponen, Jukka Jolkkonen, Susanna Koponen, Eero Castrén, Garry Wong, Annakaisa Haapasalo, Tommi Saarelainen, Leena Alhonen
Publikováno v:
Molecular and Cellular Neuroscience. 16:87-96
It has been suggested that the increased production of endogenous BDNF after brain insults supports the survival of injured neurons and limits the spread of the damage. In order to test this hypothesis experimentally, we have produced transgenic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7293c3fdc311b1ba24bb48d701ba108
https://doi.org/10.1006/mcne.2000.0863
https://doi.org/10.1006/mcne.2000.0863
Autor:
Risto A. Kauppinen, Pauli Vainio, Jouko A. Lukkarinen, Olli Gröhn, Mikko I. Kettunen, M. Johanna Silvennoinen
Publikováno v:
Magnetic Resonance in Medicine. 44:833-839
Interrelation of T1 and diffusion of water was studied in rat models of acute global and focal cerebral ischemia. Cortical T1, as quantified with an inversion recovery method, increased by 4–7% within a few minutes of global ischemia at 4.7 and 9.4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04fbf394bedf928e05c0bc4c8571a0b2
https://doi.org/10.1002/1522-2594(200012)44:6<833::aid-mrm3>3.0.co
https://doi.org/10.1002/1522-2594(200012)44:6<833::aid-mrm3>3.0.co
Autor:
M. Johanna Silvennoinen, Risto A. Kauppinen, Peter C.M. van Zijl, Jouko A. Lukkarinen, Asla Pitkänen, Olli Gröhn
Publikováno v:
Magnetic Resonance in Medicine. 42:268-276
Sensitivity of T(1) in the rotating frame (T(1rho)) to both transient cerebral ischemia and cortical hypoperfusion was studied in rats. T(1rho) is believed to probe water in close contact with macromolecules, revealing water spins with restricted rot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e2cc171f9a8c1bbecf6e25c72fac1b
https://doi.org/10.1002/(sici)1522-2594(199908)42:2<268::aid-mrm8>3.0.co
https://doi.org/10.1002/(sici)1522-2594(199908)42:2<268::aid-mrm8>3.0.co
Publikováno v:
Brain Research. 826:325-329
Ornithine decarboxylase (ODC) transgenic and α-difluoromethyl ornithine (DFMO)-treated rats were exposed to transient middle cerebral occlusion (MCAO) to examine the role of intraischaemic ODC-activity on the evolution of ischaemia-reperfusion damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf3e9b6dcf4686a331545889ed1f90ef
https://doi.org/10.1016/s0006-8993(99)01327-x
https://doi.org/10.1016/s0006-8993(99)01327-x
Autor:
Riitta Sinervirta, Aki Järvinen, Olli Gröhn, Jouko A. Lukkarinen, Juhani Jänne, Risto A. Kauppinen, Leena Alhonen, Joni M. E. Oja
Publikováno v:
European Journal of Neuroscience. 10:2046-2055
Nuclear magnetic resonance imaging (MRI) was used to study dynamics of maturation and the size of ischaemic stroke lesions in rats with greatly increased activity of ornithine decarboxylase (ODC). Syngenic rats, either with or without chronic pre-isc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd6bf820c207c868f998edd629b2d4a
https://doi.org/10.1046/j.1460-9568.1998.00216.x
https://doi.org/10.1046/j.1460-9568.1998.00216.x
Publikováno v:
Neurochemistry International. 31:95-104
The kinetics of glutamate 13 C-4 label appearance from d -[1- 13 C]-glucose and 13 C-4 label disappearance from steady state following d - 12 C-glucose incubation were quantified with 1 H-observed, 13 C-edited nuclear magnetic resonance (NMR) spectro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2497bbdbd9daffd502f2033ca73ffbbb
https://doi.org/10.1016/s0197-0186(96)00120-9
https://doi.org/10.1016/s0197-0186(96)00120-9
Autor:
Riitta Sinervirta, Risto A. Kauppinen, Leena Alhonen, Aki Järvinen, Jouko A. Lukkarinen, Olli Gröhn, Juhani Jänne
Publikováno v:
Stroke. 28:639-645
Background and Purpose Cerebral ischemia causes activation of ornithine decarboxylase (ODC) gene and subsequent accumulation of putrescine, which might either directly or indirectly affect the outcome of cerebral infarct. We developed a transgenic ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f178ffaaa9d8555fa37bcadbeb8dda0f
https://doi.org/10.1161/01.str.28.3.639
https://doi.org/10.1161/01.str.28.3.639
Autor:
Olli H J, Gröhn, Heidi I, Mäkelä, Jouko A, Lukkarinen, Lance, DelaBarre, Joseph, Lin, Michael, Garwood, Risto A, Kauppinen
Publikováno v:
Magnetic resonance in medicine. 49(1)
The ability of on-resonance T(1rho) (T(1rho)) and off-resonance T(1rho) (T(1rho)(off)) measurements to indicate acute cerebral ischemia in a rat model of transient middle cerebral artery (MCA) occlusion was investigated at 4.7 T. T(1rho) was determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca1d6934ae9fd6ce28cafe3da81085ac
https://pubmed.ncbi.nlm.nih.gov/12509834
https://pubmed.ncbi.nlm.nih.gov/12509834